Gene Information

Name : nrdF (SSUBM407_0740)
Accession : YP_003028495.1
Strain : Streptococcus suis BM407
Genome accession: NC_012926
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 811080 - 812039 bp
Length : 960 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGGAAACCTACTACAAAGCCATAAACTGGAACGCCATTGAGGATGTTATTGACAAGTCAACTTGGGAAAAGTTGACTGA
GCAATTCTGGCTCGATACACGTATTCCTTTATCAAACGACTTGGATGACTGGCGTAAACTTACTGCTGAAGAAAAAGACC
TGGTTGGTAAGGTCTTTGGCGGATTGACCCTCTTGGATACCCTTCAATCTGAAACAGGTGTCCAAGCCCTCCGCAATGAC
ATTCGCACACCCCATGAAGAAGCTGTTTACAACAATATTCAATTCATGGAGTCTGTTCACGCCAAATCTTACTCTTCTAT
CTTCTCAACCTTGAATACCAAGTCTGAGATTGAAGACATCTTTGAATGGACCAACAGCAACGAATATTTGCAACGCAAGG
CAAAGATTATCAATGAAATCTACGAAACAGGTACACCACTTGAAAAGAAAGTAGCCAGCGTATTCCTTGAAACCTTCCTC
TTCTACTCTGGTTTCTTCACGCCACTCTACTACCTTGGGAATAACAAACTGGCCAACGTTGCAGAAATCATCAAACTGAT
TATCCGTGACGAATCTGTGCACGGTACCTACATTGGCTACAAGTTCCAGCTTGGTTTCAATGAATTATCAGAGGAAGAAC
AGGACAAACTTCGCGACTGGATGTACGACCTGCTCTACCAACTTTACGAAAATGAAGAGGGCTATACACGCTCCCTCTAT
GATGCAGTTGGCTGGACTGAGGAAGTCTTGACTTTCCTTCGTTACAACGCCAACAAAGCCCTCATGAACTTGGGACAAGA
TCCACTCTTCCCAGATTCAGCAGATGATGTCAACCCAATCATCATGAACGGTATCTCAACCGGTACATCTAACCACGACT
TCTTCTCCCAAGTCGGTAACGGCTATCTTCTTGGTGAAGTGGAAGCTATGACAGATGATGATTATTTATATGGGTTGTAG

Protein sequence :
METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDWRKLTAEEKDLVGKVFGGLTLLDTLQSETGVQALRND
IRTPHEEAVYNNIQFMESVHAKSYSSIFSTLNTKSEIEDIFEWTNSNEYLQRKAKIINEIYETGTPLEKKVASVFLETFL
FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELSEEEQDKLRDWMYDLLYQLYENEEGYTRSLY
DAVGWTEEVLTFLRYNANKALMNLGQDPLFPDSADDVNPIIMNGISTGTSNHDFFSQVGNGYLLGEVEAMTDDDYLYGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 3e-74 51