Gene Information

Name : leuS (SSUBM407_1933)
Accession : YP_003029622.1
Strain : Streptococcus suis BM407
Genome accession: NC_012926
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2032431 - 2034932 bp
Length : 2502 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGCTTCTATAATCACAAGGAAATCGAGCCCAAATGGCAAGAATTTTGGGCAAAAAATCATACTTTTAAGACAGGAAC
AGATGCAGAAAAGCCAAACTTTTATGCCCTAGATATGTTCCCTTATCCGTCTGGTGCGGGCTTGCACGTTGGTCACCCTG
AGGGCTATACGGCGACGGACATTCTCAGCCGTTACAAGCGTGCCCAAGGTTACAACGTTCTTCACCCAATGGGTTGGGAT
GCCTTTGGTCTGCCAGCTGAGCAATACGCTATGGATACAGGCAATGACCCAGCTGACTTTACGGCGGAAAATATTGCCAA
CTTCAAACGTCAGATTAACGCCCTTGGCTTTTCTTACGACTGGGACCGCGAGGTTAATACGACTGACCCTAACTACTACA
AGTGGACTCAGTGGATTTTCACCAAATTGTATGAAAAAGGCCTAGCCTATGAGGCAGAAGTGCCTGTAAACTGGGTAGAA
GAATTGGGAACAGCTATCGCCAACGAAGAGGTCCTTCCTGACGGAACGTCTGAACGTGGTGGTTATCCAGTTGTCCGCAA
GCCAATGCGCCAATGGATGTTGAAAATAACGGCCTATGCAGAGCGTTTGCTTAATGACTTAGAAGAAGTTGATTGGCCAG
AGTCTATCAAGGATATGCAACGCAACTGGATTGGCAAGTCTACGGGTGCCAATGTGACTTTTAAGATTAAGGACACAGAT
AAGGACTTCACAGTCTTTACTACCCGTCCTGACACCCTTTTCGGTGCGACCTACGCAGTCCTTGCCCCTGAGCATGACTT
GGTAGATAGTATCACATCAGCTGAACAAGCAGAAGCTGTGGCAGAATACAAACGCCAAGCCTCTCTCAAATCAGACCTGG
CTCGTACTGACCTGGCTAAAGACAAGACCGGTGTCTGGACAGGTGCTTATGCCATCAACCCTGTCAACGGTAAAGAAATT
CCAATCTGGATTGCCGACTATGTACTGGCAAGCTACGGAACAGGTGCTATCATGGCCGTTCCTGCTCATGACGAGCGTGA
CTGGGAATTTGCCAAACAGTTTGGTTTGGACATTATTCCAGTTCTGGAAGGTGGCAATGTAGAAGAAGCTCCTTACACAG
AGGACGGTGCCCACATCAATTCTGATTTCCTAGATGGTCTTAACAAGGAAGAAGCTATTGCCAAAATGGTAGCTTGGTTG
GAAGAAAACGGTGTCGGTCAGGAGAAGATTTCTTACCGCCTCCGCGACTGGCTCTTCAGCCGCCAGCGTTATTGGGGTGA
GCCAATTCCAATCATCCACTGGGAAGATGGAACTTCCACAGCCGTACCAGAAAATGAGTTACCTTTGGTATTGCCAAAAA
CCTCAGACATCAAGCCTTCAGGTACAGGGGAGTCACCTCTTGCTAACTTGACAGACTGGTTGGAAGTGGTGCGTGAAGAC
GGTGTTAAAGGTCGCCGTGAAACCAACACTATGCCACAATGGGCGGGTTCTAGCTGGTACTACCTCCGCTATATCGACCC
GCACAATGATGAGAAATTGGCAGACGAGGATCTTCTCAAAGCTTGGTTGCCAGTGGACATCTACATCGGTGGTGCTGAGC
ACGCAGTCCTTCACCTGCTCTACGCTCGCTTCTGGCACAAGTTCCTTTACGACCTTGGCGTTGTGCCGACCAAAGAGCCA
TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACTAGCTACCGCGACAGCCGTGGTGCCCTTGTAGCGACAGATAA
AGTTGAAAAACGCGATGGGTCCTTCTTCCACATGGAAACTGGTGAAGAGTTGGAGCAGGCACCTGCTAAGATGTCTAAGT
CTCTTAAAAACGTGGTTAACCCAGATGATGTGGTCGAGCAATTCGGTGCGGACACTCTCCGTGTTTATGAAATGTTCATG
GGTCCACTTGATGCGTCAATCGCTTGGTCAGAAGAAGGTCTCGAAGGCAGCCGTAAGTTCCTTGACCGTGTCTATCGCCT
CTTAACCACTAAGGAGCTTGTGGCGGAAAATAGCGGAGCGCTTGATAAAGTTTACAATGAAACTGTGAAGACGGTGACAG
AGCATATTGAAGACCTGAAATTCAACACAGCTATCGCCCAGCTCATGATTTTTGTCAACGCAGCCAACAAGGAAGACAAG
CTTTATGTTGACTACGCCAAAGGTTTTGTCCAATTGATCGCCCCATTTGCACCACACTTGGCAGAAGAACTCTGGCAGGG
TCTTGCAAATACAGGCCAGTCAATCAGCTATGTCGCATGGCCAACATATGACGAAAGCAAGCTGGTAGAAAGCGAAGTGG
AAATCGTTGTCCAAATCAAAGGCAAGGTAAAAGCTCGCTTGACCGTAGCCAAAGACTTAGCACCAGCTGAACTTGAAAAA
GTTGCCCTTGCAGATGAAAAAGTCCAAGCTGAAATAGCTGGTCAAACAGTGGTGAAGGTGATTAGTGTTCCGAATAAACT
AGTTAATATTGTTGTGAAATAA

Protein sequence :
MSFYNHKEIEPKWQEFWAKNHTFKTGTDAEKPNFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLEEVDWPESIKDMQRNWIGKSTGANVTFKIKDTD
KDFTVFTTRPDTLFGATYAVLAPEHDLVDSITSAEQAEAVAEYKRQASLKSDLARTDLAKDKTGVWTGAYAINPVNGKEI
PIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFGLDIIPVLEGGNVEEAPYTEDGAHINSDFLDGLNKEEAIAKMVAWL
EENGVGQEKISYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPENELPLVLPKTSDIKPSGTGESPLANLTDWLEVVRED
GVKGRRETNTMPQWAGSSWYYLRYIDPHNDEKLADEDLLKAWLPVDIYIGGAEHAVLHLLYARFWHKFLYDLGVVPTKEP
FQKLFNQGMILGTSYRDSRGALVATDKVEKRDGSFFHMETGEELEQAPAKMSKSLKNVVNPDDVVEQFGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLLTTKELVAENSGALDKVYNETVKTVTEHIEDLKFNTAIAQLMIFVNAANKEDK
LYVDYAKGFVQLIAPFAPHLAEELWQGLANTGQSISYVAWPTYDESKLVESEVEIVVQIKGKVKARLTVAKDLAPAELEK
VALADEKVQAEIAGQTVVKVISVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 90