Gene Information

Name : tetM2 (SSUBM407_0983)
Accession : YP_003028727.1
Strain : Streptococcus suis BM407
Genome accession: NC_012926
Putative virulence/resistance : Resistance
Product : tetracycline resistance protein TetM 2
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0480
EC number : -
Position : 1064191 - 1066110 bp
Length : 1920 bp
Strand : +
Note : Similar to SSUBM4070483, 94.8% identity (98.7% similar) in 639 aa overlap

DNA sequence : 
ATGAAAATTATTAATATTGGAGTTTTAGCTCATGTTGATGCAGGAAAAACTACCTTAACAGAAAGCTTATTATATAACAG
TGGAGCGATTACAGAATTAGGAAGCGTGGACAAAGGTACAACGAGGACGGATAATACGCTTTTAGAACGTCAGAGAGGAA
TTACAATTCAGACAGGAATAACCTCTTTTCAGTGGGAAAATACGAAGGTGAACATCATAGACACGCCAGGACATATGGAT
TTCTTAGCAGAAGTATATCGTTCATTATCAGTTTTAGATGGGGCAATTCTACTGATTTCTGCAAAAGATGGCGTACAAGC
ACAAACTCGTATATTATTTCATGCACTTAGGAAAATGGGGATTCCCACAATCTTTTTTATCAATAAGATTGACCAAAATG
GAATTGATTTATCAACGGTTTATCAGGATATTAAAGAGAAACTTTCTATGGAAATTATAATCAAACAGAAAGTAGAGCTG
CACCCTAATATGTGTGTGATGAGCTGTACGGAACCTGAGCAATGGGATGTGGTAATAGAAGGAAATGATGACCTTTTAGA
GAAATATATGTCCGGTAAATCATTAGAAGCATTAGAACTCGAACAAGAGGAAATCAGAAGATTTCAGAATTGCTCCTTGT
ACCCTGTTTATCATGGAAGCGCAAAAAGCAACATAGGGATTGAGCAGCTTATAGAAGTGATAACGAATAAATTTTATTCA
TCAACATACAGAAAGAAGTCTGAACTTTGCGGAAATGTCTTCAAAATTGAATATTCGGAAGAAAGACAACGTCTTGCATA
TGTACGCCTTTATGGCGGAATCCTGCATTTGCGGGATTCGGTTAGAATATCGGAAAAGGAAAAAATAAAAATTACAGAAA
TGTATACTTCAATAAATGGTGAATTATGTAAAATTGATAAGGCTTATTCCGGGGAAATTGTTATTTTGCAAAATGAGTTT
TTGAAGCTAAATAGTGTTCTTGGAGATACAAAGCTATTGCCACAGAGAGAGAGAATTGAAAATCCGCTCCCTCTGCTGCA
AACAACTGTTGAACCGAGCAAACCTCAACAAAGGGAAATGTTACTTGATGCACTTTTAGAAATCTCCGACAGTGACCCGC
TTCTACAATATTATGTGGATTCTACGACACATGAAATTATACTTTCTTTCTTAGGGAAAGTACAAATGGAAGTGATTAGT
GCACTGTTGCAAGAAAAGTATCATGTGGAGATAGAACTAAAAGAGCCTACAGTCATTTATATGGAGAGACCGTTAAAAAA
TGCAGAATATACCATTCACATCGAAGTGCCGCCAAATCCTTTCTGGGCTTCCATTGGTTTATCTGTATCACCGCTTCCGT
TGGGAAGTGGAATGCAGTATGAGAGCTCGGTTTCTCTTGGATACTTAAATCAATCATTTCAAAATGCAGTTATGGAAGGG
ATACGCTATGGTTGCGAACAAGGATTATATGGTTGGAATGTGACGGATTGTAAAATCTGTTTTAAGTATGGCTTATACTA
TAGCCCTGTTAGTACCCCAGCAGATTTTCGGATGCTTGCTCCTATTGTATTGGAACAAGTCTTAAAAAAAGCTGGAACAG
AATTGTTAGAGCCATATCTTAGTTTTAAAATTTATGCGCCACGGGAATATCTTTCACGAGCATACAACGATGCTCCTAAA
TATTGTGCGAACATCGTAGACACTCAATTGAAAAATAATGAGGTCATTCTTAGTGGAGAAATCCCTGCTCGGTGTATTCA
AGAATATCGTAATGATTTAACTTTCTTTACAAATGGACGTAGCGTTTGTTTAACAGAGTTAAAAGGATATCAGGTTACCA
CTGGCGAACCTGTTTGCCAGCCCCGTCGTCCAAATAGTCGGATAGATAAAGTACGATATATGTTCAATAAAATAACTTAG

Protein sequence : 
MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMD
FLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL
HPNMCVMSCTEPEQWDVVIEGNDDLLEKYMSGKSLEALELEQEEIRRFQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYS
STYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEF
LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVIS
ALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEG
IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPREYLSRAYNDAPK
YCANIVDTQLKNNEVILSGEIPARCIQEYRNDLTFFTNGRSVCLTELKGYQVTTGEPVCQPRRPNSRIDKVRYMFNKIT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU05_0922 YP_001198287.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 99
SSU98_0928 YP_001200485.1 translation elongation factor (GTPases) Not tested 89K Protein 0.0 99
tetO AFJ97266.1 truncated tetracycline resistant protein Not tested Not named Protein 8e-164 75
tet(W) YP_005160006.1 tetracycline resistance protein Not tested Not named Protein 0.0 69

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 AM180355.1.gene636.p Protein 0.0 96
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 M85225.gene.p01 Protein 0.0 95
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 X04388.gene.p01 Protein 0.0 94
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 NC_009782.5559075.p0 Protein 0.0 93
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 NC_002758.1120355.p0 Protein 0.0 93
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 L09756.gene.p01 Protein 0.0 80
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 AJ295238.gene.p01 Protein 0.0 72
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 AJ222769.gene.p01 Protein 0.0 69
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 DQ294299.gene.p01 Protein 0.0 69
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 AY485126.gene.p01 Protein 0.0 69
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 FN594949.1.gene24.p0 Protein 0.0 67
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 AJ514254.gene.p01 Protein 7e-125 44
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 L42544.gene.p01 Protein 1e-129 44
tetM2 YP_003028727.1 tetracycline resistance protein TetM 2 Z21523.gene.p01 Protein 2e-109 41