Gene Information

Name : aadE (SSUBM407_0955)
Accession : YP_003028700.1
Strain : Streptococcus suis BM407
Genome accession: NC_012926
Putative virulence/resistance : Resistance
Product : streptomycin adenylyltransferase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1035371 - 1036234 bp
Length : 864 bp
Strand : -
Note : CDS is possiby truncated in the C-terminal region

DNA sequence :
ATGAGATCAGAAAAAGAAATGATGGATTTAGTACTTTCTTTAGCAGAACAGGATGAACGTATTCGAATTGTGACCCTTGA
GGGGTCACGCGCAAATATTAATATACCTAAAGATGAATTTCAGGATTATGATATTACATATTTTGTAAGTGATATAGAAC
CGTTTATATCTAATGATGACTGGCTTAATCAATTTGGGAATATAATAATGATGCAAAAGCCGGAGGATATGGAATTATTC
CCACCTGAAGAAAAGGGATTTTCCTATCTTATGCTATTTGATGATTACAATAAAATTGATCTTACCTTATTGCCCTTGGA
AGAGTTAGATAATTACCTAAAGGGCGATAAATTAATAAAGGTTCTAATTGATAAAGATTGTAGAATTAAAAGGGACATAG
TTCCGACTGATATAGATTATCATGTAAGAAAGCCAAGCGCAAGGGAGTATGATGATTGCTGCAATGAATTTTGGAATGTA
ACACCTTATGTTATTAAAGGATTGTGCCGCAAAGAGATACTGTTTGCAATCGATCATCTGAACCAGATTCTACGGTTTGA
ACTACTTAGGATGATGTCGTGGAAGGTTGGGATAAAGACAGAATTTTCATTAAGTGTTGGGAAAAATTATAAGTATATTA
ACAAATACATTGATGAAGATCTATGGAATAGATTATTATCTACATATCGCATGGATTCCTATGAAAATATTTGGAAGTCA
TTATTTATATGCCACCAATTGTTCAGGGAAGTGTCCAAAGAGGTAGCAGAACTACTGGGGTTTGATTATCCAGAGTATGG
TAAGAACATAACAAGATATACCGAGGACATGTATAAAAAATATGTTGAAAATGACTATTTTTAA

Protein sequence :
MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYDITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELF
PPEEKGFSYLMLFDDYNKIDLTLLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
TPYVIKGLCRKEILFAIDHLNQILRFELLRMMSWKVGIKTEFSLSVGKNYKYINKYIDEDLWNRLLSTYRMDSYENIWKS
LFICHQLFREVSKEVAELLGFDYPEYGKNITRYTEDMYKKYVENDYF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSU05_0957 YP_001198323.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 2e-131 100
SSU98_0964 YP_001200522.1 aminoglycoside 6-adenylyltansferase Not tested 89K Protein 2e-131 100
aadE YP_003446812.1 streptomycin aminoglycoside 6-adenyltransferase Not tested The aminoglycoside resistance gene cluster Protein 8e-114 83
aadE AFJ97257.1 streptomycin aminoglycoside 6-adenyltransferase Not tested Not named Protein 8e-85 83
aadE AFJ97264.1 putative adenyltransferase Not tested Not named Protein 2e-85 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadE YP_003028700.1 streptomycin adenylyltransferase NC_006663.1.orf0.gen Protein 4e-110 89
aadE YP_003028700.1 streptomycin adenylyltransferase AJ489618.1.orf2.gene Protein 1e-84 80
aadE YP_003028700.1 streptomycin adenylyltransferase FN594949.1.gene25.p0 Protein 2e-85 62