Gene Information

Name : guaA (SSU0816)
Accession : YP_003026697.1
Strain : Streptococcus suis P1/7
Genome accession: NC_012925
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 846386 - 847936 bp
Length : 1551 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAAAACAAGATGTCCAAAAAATTATTGTATTGGATTATGGTAGTCAGTACAACCAACTTATTTCACGTCGAATTCG
TGAATTTGGTGTCTTTTCAGAATTGAAAAACCATAAAATTACAGCTGAGGAAGTCCGTGCTATCAATCCAATTGGTATCG
TTCTTTCAGGTGGACCAAACTCTGTCTACGCAGAAAATGCCTTTGATATTGATCCAGAAATCTTTGAATTGGGTATTCCT
ATCTTAGGGATTTGCTATGGTATGCAGTTAATTACCCATAAATTGGGAGGTAAGGTTGTTCCTGCTGGTGAGGCTGGAAA
TCGTGAATATGGTCAATCAAATCTTCAACTGAAGACTGAATCAGCGCTTTTTGCTGGAACACCAGAAGAACAGCTTGTAC
TCATGAGCCACGGGGATGCTGTAACTGAAATTCCTGCTGATTTCCACCTGGTTGGTCTTTCTGCTGACTGCCCTTACGCA
GCCATTGAAAACACGGAACGCCGTATCTACGGTATCCAGTTCCACCCAGAAGTTCGTCATTCCGTATATGGAAACGATAT
TTTGAAAAACTTTGCGTTTGGTATCTGTGGAGCCAAAGGCGACTGGACAATGGAAAACTTCATCGAAACAGAAATTGAAA
AAATCCGCCAGACTGTTGGGGACAAGAAAGTCTTGCTCGGTTTGTCAGGCGGTGTAGATTCGTCTGTTGTTGGGGTCCTT
CTTCAACGTGCTATTGGTGACCAATTGACCTGTATCTTCGTTGACCACGGTCTTCTTCGTAAGAATGAAGGTGATCAGGT
TATGGAGATGTTGGGCGGTAAATTTGGCCTCAATATTATTCGCGTCGATGCTGCTAAGCGTTTCTTAGACCTACTTGCTG
GCGTATCTGACCCTGAGAAGAAACGTAAAATCATCGGTAATGAATTTGTTTACGTATTTGACGATGAAGCGAGCAAGTTG
ACTGATGTTGAATTCCTAGCGCAAGGAACACTTTATACCGATATTATCGAGTCAGGAACGGATACTGCTGAGACAATCAA
ATCTCACCACAACGTTGGTGGTCTGCCAGAAGATATGCAGTTCAAGTTGATTGAACCGCTCAATACTCTCTTTAAGGATG
AAGTTCGTGCCCTCGGTACTGCTCTTGGTATGCCGGATGAAGTTGTATGGCGCCAACCATTCCCAGGACCAGGCCTTGCC
ATTCGTGTCATGGGTGAAATCACTGAGGAAAAACTTCAAACTGTTCGCGAATCTGACGCTATCTTGCGTGAGGAAATTGC
AAAAGCAGGTCTTGACCGCGATGTGTGGCAATATTTCACGGTTAATACTGGCGTTCGCTCCGTAGGTGTCATGGGAGATG
GTCGTACCTACGACTACACTATCGCTATCCGTGCTATCACTTCTGTCGATGGAATGACAGCTGACTTTGCCAAACTACCA
TGGGATGTTCTTCAAAAAATCTCTGTCCGTATCGTAAACGAAGTCGACCACGTCAACCGCATCGTCTATGATATAACAAG
TAAACCACCAGCAACAGTTGAGTGGGAATAA

Protein sequence :
MTKQDVQKIIVLDYGSQYNQLISRRIREFGVFSELKNHKITAEEVRAINPIGIVLSGGPNSVYAENAFDIDPEIFELGIP
ILGICYGMQLITHKLGGKVVPAGEAGNREYGQSNLQLKTESALFAGTPEEQLVLMSHGDAVTEIPADFHLVGLSADCPYA
AIENTERRIYGIQFHPEVRHSVYGNDILKNFAFGICGAKGDWTMENFIETEIEKIRQTVGDKKVLLGLSGGVDSSVVGVL
LQRAIGDQLTCIFVDHGLLRKNEGDQVMEMLGGKFGLNIIRVDAAKRFLDLLAGVSDPEKKRKIIGNEFVYVFDDEASKL
TDVEFLAQGTLYTDIIESGTDTAETIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRALGTALGMPDEVVWRQPFPGPGLA
IRVMGEITEEKLQTVRESDAILREEIAKAGLDRDVWQYFTVNTGVRSVGVMGDGRTYDYTIAIRAITSVDGMTADFAKLP
WDVLQKISVRIVNEVDHVNRIVYDITSKPPATVEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-171 70
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-171 70
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-171 70
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-120 51