Gene Information

Name : pyk (SSU0495)
Accession : YP_003026421.1
Strain : Streptococcus suis P1/7
Genome accession: NC_012925
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 528624 - 530129 bp
Length : 1506 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAACAAACGTGTTAAAATTGTTGCAACCCTTGGTCCAGCGGTAGAAATCCGCGGTGGTAAAAAATTCGGTGACGATGG
TTACTGGGGTGAAAAATTAGATGTTGAGTCATCAGCACAGAAAATCGCTGCTTTGATTACAGAAGGTGCCAATGTTTTCC
GTTTCAACTTCTCACACGGTGACCACCAAGAGCAAGGTGATCGTATGGCAACAGTTCGTCGTGCAGAAGAAATCGCTGGT
AAAAAAGTAGGTTTCTTGTTGGATACAAAAGGTCCAGAAATCCGTACAGAATTGTTTGAAGATGATGCAAAAGAATACGC
ATATACAACTGGTGACAAATTGCGTGTTGCTACAAAACAAGGTATCAAATCTACAAAAGAAGTGATTGCTTTGAACGTAG
CAGGTGGTTTGGATGTCTTTGACGATGTTGAAGTTGGTAAGCAAATCCTTGTTGACGATGGTAAACTTGGTTTGACAGTT
GTTGAAAAAGATGCAGTAAACCGTGAATTTGTTGTTTTGGTTGAAAACGACGGTGTAATTGCTAAACAAAAAGGTGTAAA
CATCCCTTACACAAAAATTCCTTTCCCAGCTCTTGCAGAGCGTGATAATGCAGATATCCGCTTCGGTCTTGAGCAAGGTT
TGAACTTTATTGCTATCTCATTTGTACGTACTGCAAAAGACGTAGAAGTTGTTCGTAATATCTGTAAAGAAACTGGTAAC
GACCACGTTCAATTGTTTGCGAAAATCGAAAACCAACAAGGTATCGACAACATCGACGAAATCATCGAAGCAGCAGATGG
TATCATGATTGCTCGTGGTGACATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATTATCACTA
AAGTGAATGCAGCTGGTAAAGCAGTTATCACAGCAACAAACATGTTGGAAACAATGACTGAAAAACCACGTGCAACTCGT
TCTGAAGTATCTGACGTATTCAATGCTGTTATCGACGGTACTGATGCAACAATGCTTTCAGGCGAGTCTGCAAACGGTAA
ATATCCAGTAGAATCAGTTCGTACAATGGCAACTATCGCTAAAAACGCACAGACTCTTCTTAATGAATATGGTCGTTTGA
ACTCTGATCAGTTTAATCGTGCCTCTAAAACAGAAGTTATTGCTTCTGCAGTAAAAGACGCATGTCACTCAATGGACATC
AAACTAGTTGTAACAGTTACAGAAACAGGTTACTCAGCTCGTTCGATCTCTAAATACCGTCCAGATGCGGACATCTTGGC
AGTAACATTTACTGAGAAAGTACAAAAATCATTGATGCTTAACTGGGGTGTTATTCCAATTGTAACAAACCGTCCAGATT
CAACTGACGATATGTTTGATTTGGCTGAACGTATTGCCAAAGAGCAAGGTCTTGTTGAAGCAGGAGATGACATTATTATC
GTTGCTGGTGTGCCTGTAGGTGTTGCAGGTTCAACAAATACTATGCGTGTTCGTACAGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGDDGYWGEKLDVESSAQKIAALITEGANVFRFNFSHGDHQEQGDRMATVRRAEEIAG
KKVGFLLDTKGPEIRTELFEDDAKEYAYTTGDKLRVATKQGIKSTKEVIALNVAGGLDVFDDVEVGKQILVDDGKLGLTV
VEKDAVNREFVVLVENDGVIAKQKGVNIPYTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEVVRNICKETGN
DHVQLFAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKAVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIAKNAQTLLNEYGRLNSDQFNRASKTEVIASAVKDACHSMDI
KLVVTVTETGYSARSISKYRPDADILAVTFTEKVQKSLMLNWGVIPIVTNRPDSTDDMFDLAERIAKEQGLVEAGDDIII
VAGVPVGVAGSTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-65 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-64 42
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-65 42
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-65 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_003026421.1 pyruvate kinase VFG0479 Protein 2e-65 42