Gene Information

Name : smpB (SSU1218)
Accession : YP_003027073.1
Strain : Streptococcus suis P1/7
Genome accession: NC_012925
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1247789 - 1248256 bp
Length : 468 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGGCCAAGGGTGAGGGCAATGTGATTGCGCAAAATAAAAAAGCCCGCCACGACTATACCATTGTCGATACAGTGGAGGC
GGGGATGGTCCTGACGGGGACGGAGATTAAGTCTATTCGTGCGGGGCGGATCAACCTTAAGGACGGCTTTGCCCAGATCA
AGCAGGGCGAGGCTTGGTTGGTCAATGTCCATATCGCTCCCTACGATGAGGGCAATATCTGGAATCAGGAGCCAACACGG
ACCCGCAAGCTCCTCTTGCGGAAGAAGCAAATCGAGTCTTTGGACAATGAGGTCAAGGGAACAGGGATGACTCTGGTGCC
CCTCAAGGTCTATATCAAGGATGGCTTTGCCAAGGTTTTGATTGGGCTTGCCAAAGGGAAGCACGACTACGACAAGCGGG
AGTCAATTAAACGCCGTGAGCAAGACCGTGATATCAAACGAACCATGAAGGCTATCAATAGTCGATAG

Protein sequence :
MAKGEGNVIAQNKKARHDYTIVDTVEAGMVLTGTEIKSIRAGRINLKDGFAQIKQGEAWLVNVHIAPYDEGNIWNQEPTR
TRKLLLRKKQIESLDNEVKGTGMTLVPLKVYIKDGFAKVLIGLAKGKHDYDKRESIKRREQDRDIKRTMKAINSR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 5e-39 57
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-36 51
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-22 43