Gene Information

Name : lysS (SSUSC84_0454)
Accession : YP_003024496.1
Strain : Streptococcus suis SC84
Genome accession: NC_012924
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 501420 - 502910 bp
Length : 1491 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCAACTGAACATTTTGAAGAATTAAATGACCAACAGATTGTCCGTCGTGAGAAAATGACGGCTCTTGCTGAACAAGG
CATTGACCCATTTGGAAAACGTTTTGAGCGTTCTGCCAACTCAGCTGAATTGAAGGCCCAGTACGAAGACAAATCAAAAG
AAGACTTGGAAGAATTAGGGCAAACAGCAATCATTGCAGGTCGTATTATGACCAAGCGTGGTAAGGGTAAGGCAGGTTTT
GCTCACATTCAAGACCGCGAAGGCCAGATTCAGATCTACGTTCGTAAGGATGATGTTAGCGAAGAAAACTATGAAATCTT
CAAAAAAGCAGACCTAGGTGACTTTATCGGTGTCGAGGGAGATGTCTTCAAGACAAACGTTGGTGAGTTGTCTATCCATG
CTCGCAAGTTGACTCACTTGTCTAAAGCGCTCCGCCCATTGCCAGAAAAATTCCACGGTTTGACAGACATCGAGACCCGC
TACCGCAAACGTTATTTGGACTTGATTACTAACCGCGAGAGCTTTGATCGCTTTGTGACCCGCTCAAAAATTATCTCAGA
AATCCGCCGTTACCTTGACGGACTTGGTTTCTTGGAAGTGGAAACACCAGTTCTTCACAACGAAGCTGGTGGTGCTGCAG
CTCGTCCATTCATCACCCACCACAATGCCCAAAACATTGACATGGTCCTTCGTATCGCGACAGAACTCCACCTCAAACGC
CTGATTGTCGGCGGTATGGAACGCGTTTATGAAATCGGCCGCATCTTCCGTAACGAAGGTATGGATGCGACCCACAACCC
TGAGTTCACTTCCATTGAGGTTTACCAAGCTTATGCAGACTACCAAGACATCATGGACTTGACCGAAGGTATTATCCAGC
ACACTGCCAAGGCTGTTGTCGGTGATGGTCCGGTGACTTATCAGGGCACTGAAATTGCTATCCACGAGCCATTCAAGCGT
ATCCACATGGTTGACGCTATTAAGGAACAAACTGGCGTGGACTTCTGGCAAGAGATGAGCTTCGAGGAAGCAAAAGCCCT
TGCAGCTGAGCACAAGGTCCCTGTGGAAAAACACCATACAGAAGTTGGTCAAATCATCAACAGCTTCTTTGAAGAATACG
TTGAAGCAACTCTTATCCAACCAACCTTTGTCTATGGTCACCCAGTAGCCGTATCTCCACTGGCTAAGAAAAACGATGAA
GACCCACGCTTCACAGATCGCTTCGAGCTCTTCATCATGACCAAGGAATACGGAAATGCCTTTACAGAATTGAACGACCC
AATCGACCAATTGGAACGCTTTGAAGCCCAAGCCAAGGCTAAAGAACTCGGTGACGACGAAGCGACAGGCGTTGACTACG
ACTACATCGAAGCCCTCGAATACGGTATGCCACCAACAGGTGGACTTGGAATCGGTATCGACCGCCTCTGCATGCTCTTG
ACAGATACAACTACTATTCGGGATGTGTTGCTATTCCCTACTATGAAGTAA

Protein sequence :
MSTEHFEELNDQQIVRREKMTALAEQGIDPFGKRFERSANSAELKAQYEDKSKEDLEELGQTAIIAGRIMTKRGKGKAGF
AHIQDREGQIQIYVRKDDVSEENYEIFKKADLGDFIGVEGDVFKTNVGELSIHARKLTHLSKALRPLPEKFHGLTDIETR
YRKRYLDLITNRESFDRFVTRSKIISEIRRYLDGLGFLEVETPVLHNEAGGAAARPFITHHNAQNIDMVLRIATELHLKR
LIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQAYADYQDIMDLTEGIIQHTAKAVVGDGPVTYQGTEIAIHEPFKR
IHMVDAIKEQTGVDFWQEMSFEEAKALAAEHKVPVEKHHTEVGQIINSFFEEYVEATLIQPTFVYGHPVAVSPLAKKNDE
DPRFTDRFELFIMTKEYGNAFTELNDPIDQLERFEAQAKAKELGDDEATGVDYDYIEALEYGMPPTGGLGIGIDRLCMLL
TDTTTIRDVLLFPTMK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-111 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_003024496.1 lysyl-tRNA synthetase VFG1668 Protein 1e-111 48