Gene Information

Name : clpL (SSUSC84_0338)
Accession : YP_003024386.1
Strain : Streptococcus suis SC84
Genome accession: NC_012924
Putative virulence/resistance : Virulence
Product : ATP-dependent protease ATP-binding subunit ClpL
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 372600 - 374699 bp
Length : 2100 bp
Strand : +
Note : Orthologue of S. suis P17 (AM946016) SSU0352

DNA sequence :
ATGAACAACAATTTCAATAACTTTAACAATATGGACGACATTTTCAATCAACTCATGGGCAACATGGGTGGCTACAGCAC
AGAACGTCGCCGTTATTCTATCAATGGGCGTGAAGTGACACCAGAAGAATTTGCTATGTACCGTCAGACTGGTCGCCTGC
CACAGACAGAAGAAGTGGCTCAAACACAGGCTAAAGGTCAGATAAAGTCAGACGGAATTCTTGCAAAACTTGGTCGCAAT
TTGACACAAGATGCGCGTGAAGGTAAGTTGGATCCAGTCATTGGACGAAACAAGGAAATCCAAGAAACCTCTGAAATCCT
AGCTCGCCGTACGAAAAATAATCCTGTTTTGGTCGGTGATGCTGGTGTCGGAAAGACAGCGGTAGTAGAAGGATTGGCTC
AAGCCATTGTCAATGGTGATGTGCCAGCAGCCATTAAGAACAAGGAAATCATCTCCATCGACATTTCAGGCTTGGAGGCT
GGGACTCAGTATCGTGGAGCTTTTGAGGAAAATGTGCAGAATCTTGTGGATGAAGTCAAAAAAGCTGGAAATATCATTCT
CTTCTTTGATGAAATTCATCAGATTTTGGGAGCTGGTAGCACTGGCGGAGACTCAGGTTCCAAGGGTTTAGCGGATATTC
TCAAACCAGCTTTATCCCGTGGGGAATTGACGGTTATCGGTGCCACTACACAGGACGAATACCGCAATACTATTCACAAG
AATGCTGCTCTGGCTCGTCGTTTCAATGAAGTCAAGGTCAATGCTCCGTCCGCAGAGGACACCTACCAGATTTTGAAAGG
GATTAAGCCGCTTTATGAAGCCCACCACAATATTGAATTGCCAGATGAGGTTTTGAGAGCTGCGGTTGATTATTCCGTCC
AATATATTCCACAACGTAGCTTGCCTGATAAGGCTATTGACCTAGTCGATGTGACCGCTGCACATTTGGCTGCACAACAT
CCTGTGACAGATATTCAGACCTTAGAAGCAGAAATGGCTGAGGCAAAACAGTTGCAGTTGGAAGCAGCTGAAAAAGAGGA
TTATGAAAAAGCCTTGAATGAAAAAGTCCGTATTGATAAGCTACAAAAACAGATTGATAATCATACGGAGCAACAGAAAG
TGGTGGCGACTGTTAATGATGTGGCTCAGGCGGTTGAGCGGATGACAGGAATTCCAGTCTCTCAAATGGGAGCTTCTGAC
ATTGAACGACTCAAGGAATTGAAAAATCGTCTGGCAGCAAACGTTATCGGTCAAGACGATGCGGTGGAAGCTGTATCTCG
TGCCATTCGTCGGAATCGTGCAGGTTTTGATGATGGCAACCGTCCAATTGGTTCCTTCCTCTTTGTTGGTCCGACAGGTG
TGGGTAAGACAGAGTTGGCAAAACAGTTAGCACTAGACTTGTTTGGTAACAAGGATGCCATTATTCGTTTGGATATGTCT
GAATACAGCGATCGGACAGCCGTTTCCAAATTAATCGGTACCACAGCTGGCTACATTGGCTACGATGACAATTCCCATAC
TCTTACCGAGCGCGTCCGCCGCAATCCGTACTCAATCGTTCTTATGGATGAGATTGAAAAAGCTGATCCACAAGTGATTA
CCCTTCTCTTGCAAGTGCTAGATGATGGGCATTTGACTGATGGACAGGGCAACCAAGTTAACTTTAAAAATACCATTATT
ATCGCGACTTCTAATGCAGGTTTTGGTTATGGAATGGCAGAAGGTGAAGAAAATCAAGACATCATGGACCGCATCGCACC
ATTCTTCCGCCCAGAGTTTCTCAATCGTTTTAACGCAGTCATCGAGTTCAAGCATTTGGATAAAGATGATCTCAAAGCCA
TTGTAGAATTACTCTTGGCCCAGGTCAATAATACCCTGGCGAAGAAAGGCATCCAATTAACGGTAACGGAAGCTGCCAAA
GAATTCTTGATGGAAGAAGGCTATGACAAGGCCATGGGAGCCCGTCCTCTGCGCCGTGTGATTGAAAATCAGATTCGTGA
TAAGGTGACGGATTTCTATTTGGATCATGTTGATGTCAAATATCTGGAAGCGGATGTGGTTGATGGAAGCATCCAAATAA
AAGAGCAAAGCTTTGCTTAA

Protein sequence :
MNNNFNNFNNMDDIFNQLMGNMGGYSTERRRYSINGREVTPEEFAMYRQTGRLPQTEEVAQTQAKGQIKSDGILAKLGRN
LTQDAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLEA
GTQYRGAFEENVQNLVDEVKKAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTIHK
NAALARRFNEVKVNAPSAEDTYQILKGIKPLYEAHHNIELPDEVLRAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQH
PVTDIQTLEAEMAEAKQLQLEAAEKEDYEKALNEKVRIDKLQKQIDNHTEQQKVVATVNDVAQAVERMTGIPVSQMGASD
IERLKELKNRLAANVIGQDDAVEAVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLALDLFGNKDAIIRLDMS
EYSDRTAVSKLIGTTAGYIGYDDNSHTLTERVRRNPYSIVLMDEIEKADPQVITLLLQVLDDGHLTDGQGNQVNFKNTII
IATSNAGFGYGMAEGEENQDIMDRIAPFFRPEFLNRFNAVIEFKHLDKDDLKAIVELLLAQVNNTLAKKGIQLTVTEAAK
EFLMEEGYDKAMGARPLRRVIENQIRDKVTDFYLDHVDVKYLEADVVDGSIQIKEQSFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 4e-132 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpL YP_003024386.1 ATP-dependent protease ATP-binding subunit ClpL VFG0080 Protein 1e-147 48
clpL YP_003024386.1 ATP-dependent protease ATP-binding subunit ClpL VFG0079 Protein 5e-138 45