Gene Information

Name : sly (SSUSC84_1264)
Accession : YP_003025261.1
Strain : Streptococcus suis SC84
Genome accession: NC_012924
Putative virulence/resistance : Virulence
Product : suilysin (hemolysin)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1348487 - 1349980 bp
Length : 1494 bp
Strand : -
Note : Orthologue of S. suis P17 (AM946016) SSU1231

DNA sequence :
ATGAGAAAAAGTTCGCACTTGATTTTAAGCTCAATAGTCAGTTTGGCACTCGTAGGGGTCACACCATTGAGTGTTCTTGC
AGATTCCAAACAAGATATTAATCAGTATTTTCAAAGCTTGACTTACGAGCCACAAGAGATTCTTACAAATGAGGGAGAAT
ACATTGATAATCCGCCAGCAACAACTGGTATGTTAGAAAACGGACGTTTTGTAGTACTTCGCAGAGAAAAGAAGAATATT
ACGAACAATAGTGCAGATATTGCTGTTATTGATGCTAAGGCTGCAAATATTTATCCAGGTGCTTTATTGCGTGCTGACCA
AAATCTTCTGGATAATAATCCAACGCTTATCAGTATTGCGCGGGGAGATCTGACGCTTAGTTTGAATTTACCTGGTTTGG
CCAATGGGGATAGCCACACTGTTGTAAATTCTCCAACAAGAAGTACTGTTCGAACAGGGGTGAATAACCTTCTGTCTAAA
TGGAATAATACGTATGCTGGAGAGTATGGCAATACCCAAGCAGAGCTTCAATATGATGAAACAATGGCATACAGTATGTC
ACAATTGAAAACGAAGTTCGGAACCTCTTTTGAAAAAATTGCTGTACCATTAGATATCAATTTTGATGCCGTGAATTCGG
GTGAAAAACAGGTTCAGATTGTTAACTTTAAACAAATTTATTATACAGTTAGTGTTGATGAACCAGAATCTCCAAGCAAG
CTTTTTGCAGAAGGGACAACTGTAGAAGATTTGAAACGAAATGGGATAACAGATGAGGTACCTCCTGTTTATGTTTCCAG
CGTTTCTTATGGACGCTCTATGTTCATCAAGTTAGAAACTAGCAGTAGGAGTACCCAAGTTCAAGCCGCATTTAAAGCAG
CCATCAAAGGCGTTGATATTAGTGGCAATGCTGAGTATCAAGACATTCTGAAAAATACTTCATTCTCTGCTTATATTTTT
GGTGGGGATGCAGGTAGCGCGGCTACTGTTGTGAGCGGAAATATTGAAACACTGAAGAAGATTATTGAAGAAGGTGCAAG
ATACGGAAAACTCAATCCAGGTGTTCCGATTTCGTATTCAACCAACTTTGTCAAAGACAATAGACCTGCTCAGATTTTGA
GCAATTCAGAGTACATAGAAACAACTTCAACAGTCCATAATAGCAGTGCATTGACATTGGATCATTCAGGTGCTTATGTT
GCGAAATACAACATTACTTGGGAAGAAGTATCTTACAATGAAGCTGGAGAAGAAGTTTGGGAACCAAAAGCTTGGGATAA
GAATGGTGTAAATCTGACCTCACACTGGAGTGAAACCATTCAAATTCCAGGAAATGCTCGCAATCTTCATGTCAATATTC
AAGAATGTACAGGATTAGCATGGGAGTGGTGGAGAACAGTTTATGACAAAGATTTACCACTTGTTGGTCAACGTAAAATA
ACCATCTGGGGAACAACGTTATACCCACAGTATGCGGATGAGGTGATAGAGTAA

Protein sequence :
MRKSSHLILSSIVSLALVGVTPLSVLADSKQDINQYFQSLTYEPQEILTNEGEYIDNPPATTGMLENGRFVVLRREKKNI
TNNSADIAVIDAKAANIYPGALLRADQNLLDNNPTLISIARGDLTLSLNLPGLANGDSHTVVNSPTRSTVRTGVNNLLSK
WNNTYAGEYGNTQAELQYDETMAYSMSQLKTKFGTSFEKIAVPLDINFDAVNSGEKQVQIVNFKQIYYTVSVDEPESPSK
LFAEGTTVEDLKRNGITDEVPPVYVSSVSYGRSMFIKLETSSRSTQVQAAFKAAIKGVDISGNAEYQDILKNTSFSAYIF
GGDAGSAATVVSGNIETLKKIIEEGARYGKLNPGVPISYSTNFVKDNRPAQILSNSEYIETTSTVHNSSALTLDHSGAYV
AKYNITWEEVSYNEAGEEVWEPKAWDKNGVNLTSHWSETIQIPGNARNLHVNIQECTGLAWEWWRTVYDKDLPLVGQRKI
TIWGTTLYPQYADEVIE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-110 46
slo YP_281505.1 streptolysin O Virulence Not named Protein 1e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sly YP_003025261.1 suilysin (hemolysin) VFG1363 Protein 4e-117 51
sly YP_003025261.1 suilysin (hemolysin) VFG0074 Protein 1e-110 46
sly YP_003025261.1 suilysin (hemolysin) VFG2275 Protein 2e-95 42
sly YP_003025261.1 suilysin (hemolysin) VFG0976 Protein 5e-86 41