Gene Information

Name : polA (SSUSC84_1241)
Accession : YP_003025238.1
Strain : Streptococcus suis SC84
Genome accession: NC_012924
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 1319894 - 1322530 bp
Length : 2637 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGAAAAAAAATAAATTATTATTAATCGATGGCTCTTCTGTAGCCTTCCGTGCCTTCTTTGCACTCTATAACCAAATCGA
CCGCTTCAAGAATGCCAACGGTCTGCATACCAACGCCATTTACGGCTTCAATCTCATGCTGGACCACATGATGAAGCGGA
TTGAGCCGACCCACATTCTTGTGGCTTTTGATGCTGGAAAGACCACTTTCCGTACGGAGATGTATGCAGACTATAAGGCA
GGTCGTGCCAAGACTCCAGACGAATTCCGTGAGCAGTTTCCTTTTATCCGTCAGATGTTGGATGCCATGGGAGTCAAGCA
TTACGAACTGGATCAGTATGAGGCAGACGATATTATCGGTACCTTGGACAAAATGGCAGAGCGGACAGACATCCCTTTCG
ATGTGACCATTGTTAGCGGTGATAAGGATTTGATCCAGCTGACTGATGAGAACACCGTAGTCGAAATTTCCAAGAAAGGC
GTTGCCGAATTCGAAGAATTTACCCCAGCCTACCTCATGGAAAAAATGGGGATTAGCCCTACTCAGTTTATTGACCTCAA
GGCTTTGATGGGAGATAAGTCCGATAACATTCCTGGCGTGACCAAAATCGGTGAAAAAACAGGTCTAAAACTCCTGACAG
AATTTGGTTCTTTGGATGGTATCTACGAAAACATTGACAGCATGAAGGCTTCTAAGATGAAAGAAAACCTGATTGCTGAT
AAGGAGAAGGCCTTCCTATCTCGTACACTTGCTACCATTGATACTCAGGCACCAATCGAAATTGGTCTGGATGACATTGT
TTATCAAGGCCCCAAGGTGGATGAACTGGGACAATTTTATGATGACATGGGCTTCAAACAATTAAGGGCTCAGTTAGGTA
CGACCAGCTCGCAAGAGGAAGCGGTGCTCGATTTCCAAATCGTAACGGAAATCAGCCCCGCTATGCTCAAACAAGACCAG
TTTTTCTATTTTGAAATCTTGGGTGAAAATTATCACCGAGAGGATTTGGTTGGTTTAGCTTGGGGAGATAAGGAGAAAAT
CTATGTCGGAGGGCCTGAGCTACTTGATAGTCCAGTCTTGCGTGACTTTTTAGAAAGCCAAACCATAAAAACCTATGACT
TTAAGCGTGGAAAAGTTCTTCTCGACCGAAAAGAGATTAAGCTACCTCCAGCTACTTTCGATAGCCGTCTAGCCAAATAC
TTGCTTTCCACCGTTGAGGACAATTCCCTAACAACCATTGCCAACCTCTATGGTCAGACCAGTCTTGTTCCAGATGAGGC
AGTTTATGGCAAGGGTGCTAAGTTAGACTTGCCAGAACGCGAGATCTTTTTCCCACACTTGGCACGTAAGGTTCAGGTTT
TGATTGAGACAGAAGAGCCGATGTTGACCAAATTAGAAGAAAATCAGCAATTAGATCTTTTGTTTGACATGGAGTTGCCA
CTAGCAAATGTTTTAGCTAAGATGGAAATTGCTGGTATTAAAGTGGAAGCTGAGACTCTCAAAGCTATGCAATCTGAAAA
CGAAGTTTTGATTGACCAGTTGACCAAGGAAATCTATGAACTAGCTGGTCAGGAATTTAATATCAATTCGCCTAAGCAGC
TTGGGACCATTCTCTTTGAAGATATGGGACTACCATTGGAATATACCAAGAAAACCAAGACAGGCTATTCAACAGCAGTA
GATGTCTTAGAACGATTAGCGCCAATTGCACCAGTTGTTTCAAAAATCTTGGAATACCGTCAGATTACCAAGCTTCAATC
AACTTATGTAGTCGGCTTGCAGGATGCCATTTTAGAAGATGGTAAGATCCATACCCGCTATGTACAGGATTTGACACAAA
CAGGTCGTCTATCTTCAACGGACCCTAACTTGCAAAATATTCCTGTTCGTCTAGAACAAGGGCGCTTGATTCGTAAGGCA
TTTGTGCCATCGCTTGAAAATAGTGTCCTTTTGGCATCGGACTATTCACAGATTGAATTGCGCGTCTTGGCTCATATTTC
TCAGGACCAGCATTTGATTGAGGCCTTCCAGCAAGGTGCAGATATTCACACTTCGACAGCTATGCGGGTCTTCGGTATCG
AAAAAGCTGAGTATGTGACACCAAATGACCGTCGGAATGCCAAGGCTGTAAACTTCGGTGTCGTCTATGGTATTTCAGAT
TTCGGTTTATCTAATAACTTGGGGATTACACGTAAGGAAGCTAAAGCCTATATCGATACCTATTTTGAACGCTTCCCAGG
AATTAAGAATTACATGGAAACCATTGTTCGTGAGGCACGTGATAAGGGGTATGTAGAGACGATTTACAAACGCCGTCGTG
AATTACCAGATATAAACTCTCGCAATTTCAATGTCCGTAATTTTGCGGAACGAACAGCCATCAACTCACCAATTCAAGGT
TCGGCCGCAGATATTCTCAAAGTAGCCATGATTAATCTCGACAAGGCTTTGACTGAAGCAGGTCTTGCGACACGTATGTT
ATTGCAAGTACACGATGAGATTGTTTTGGAAGTCCCAGTGGCAGAGCTAGAAACGGTAAAAGCCATGGTAAAAGAGACTA
TGGAATCGGCGATTAGCCTGTCTGTACCATTGATTGCGGATGAAAATGAAGGTTCAACATGGTATGAAGCAAAGTAA

Protein sequence :
MKKNKLLLIDGSSVAFRAFFALYNQIDRFKNANGLHTNAIYGFNLMLDHMMKRIEPTHILVAFDAGKTTFRTEMYADYKA
GRAKTPDEFREQFPFIRQMLDAMGVKHYELDQYEADDIIGTLDKMAERTDIPFDVTIVSGDKDLIQLTDENTVVEISKKG
VAEFEEFTPAYLMEKMGISPTQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLTEFGSLDGIYENIDSMKASKMKENLIAD
KEKAFLSRTLATIDTQAPIEIGLDDIVYQGPKVDELGQFYDDMGFKQLRAQLGTTSSQEEAVLDFQIVTEISPAMLKQDQ
FFYFEILGENYHREDLVGLAWGDKEKIYVGGPELLDSPVLRDFLESQTIKTYDFKRGKVLLDRKEIKLPPATFDSRLAKY
LLSTVEDNSLTTIANLYGQTSLVPDEAVYGKGAKLDLPEREIFFPHLARKVQVLIETEEPMLTKLEENQQLDLLFDMELP
LANVLAKMEIAGIKVEAETLKAMQSENEVLIDQLTKEIYELAGQEFNINSPKQLGTILFEDMGLPLEYTKKTKTGYSTAV
DVLERLAPIAPVVSKILEYRQITKLQSTYVVGLQDAILEDGKIHTRYVQDLTQTGRLSSTDPNLQNIPVRLEQGRLIRKA
FVPSLENSVLLASDYSQIELRVLAHISQDQHLIEAFQQGADIHTSTAMRVFGIEKAEYVTPNDRRNAKAVNFGVVYGISD
FGLSNNLGITRKEAKAYIDTYFERFPGIKNYMETIVREARDKGYVETIYKRRRELPDINSRNFNVRNFAERTAINSPIQG
SAADILKVAMINLDKALTEAGLATRMLLQVHDEIVLEVPVAELETVKAMVKETMESAISLSVPLIADENEGSTWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 74