Gene Information

Name : guaA (GM21_0782)
Accession : YP_003020614.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 930811 - 932361 bp
Length : 1551 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCATCGACATACATTCCGAGAAGGTGCTGATCCTCGACTTCGGCTCCCAGGTAACCCAGCTCATCGCCAGGCGTGT
GAGGGAGCAGAGCGTTTACTGCGAGATCCACCCCTACAACATGGCGCTCGAGAAGATCAAGGCCTTCGCCCCGAAGGGAA
TCATCCTTTCCGGCGGCCCCTCCAGCGTCTACGACAAGGACGCCCCGCACTCCGACCTCGGCATCTACGACCTCGGCGTC
CCGGTCTTAGGCATCTGCTACGGCATGCAGCTGATGACCCAGCAGCTGGGCGGGCGCGTGGAGCGCTGCGACAAGCGTGA
ATTCGGCCGCGCCACCCTGGCCCTCGACGGCAAGAGCGAAATCTTCGCCGGCTTCGACGGCGGTGCCGAGGTCTGGATGT
CCCACGGCGACCGCATCGAGGCGATGCCGGCCGGCTTCCAGCTCATGGCGCACACCGAAGGCTGCCCCGTGGCCGCCATG
AAAGACGAGAAGCGCAACTTCTTCGGGGTCCAGTTCCACCCCGAGGTGGTGCACACCCCGCGCGGCGAAGAGATGATCGG
CAACTTCCTCTTCAACGTCTGCGGCTCGCAGCCCACCTGGACCATGGCCAACTTCATCGAGACCGAATTGGCCAGCATCC
GCGAGAAGGTCGGCACCGGCAAGGTCCTTTGCGCCCTTTCCGGCGGGGTCGACTCCGCCGTCGTCGCGGTCCTGATCCAC
AAGGCGATCGGCGATCAGCTGCACTGCGTCTTCGTCAACAACGGCCTGCTTCGCAAAGGCGAAGCCGACAAGGTGGTGAA
CCTCTTCACCAAGCATTTCAAGATCAACCTCACCCACGTCGATGCAGCGGACCGCTTCCTCGGCATGCTGGAAGGGATCT
CCGATCCGGAGCAAAAACGCAAGATCATCGGCAACGAGTTCATCTACCTCTTCGAGGAGGAGGCCAAGAAGCTGGGTCAG
GTCGATTACCTGGCGCAGGGGACCCTCTACCCCGACGTGATCGAATCCGTCTCCACCAAGGGACCCTCCGCCGTCATCAA
GAGCCATCACAACGTGGGCGGTCTCCCCGAGAAGATGAACCTGAAGCTCCTGGAGCCGGTGCGCGAGCTGTTCAAGGACG
AGGTGCGGCTTCTGGGCAAGGAGCTCGGCATGCCCGACGAGGTGGTGTACCGCCAGCCGTTCCCGGGTCCCGGCCTCGCC
ATTCGCTGCATCGGCGAACTCTCCGCGGAGAAGCTCGACATCCTGCGCGACGCCGACGCCATCGTCATCGAAGAGATCAG
GAAAGCCGGGTTATATCGCGAGATCTGGCAGTCGTTTGCCGTACTCCTGCCGGTCAAGACCGTCGGGGTCATGGGCGACG
CCAGGACCTACGAGTGGACCGTGGCGCTTCGTGCCGTCAACTCGCTCGACGGCATGACCGCTGACTGGGTCAAGCTCCCC
TACGAGCTACTTGGCAGTATTTCCTCAAGAATCATCAACGAGGTTAAGGGCGTGAACCGCGTGGTTTACGACATCAGCCA
GAAGCCCCCCGCGACCATCGAGTGGGAATAA

Protein sequence :
MTIDIHSEKVLILDFGSQVTQLIARRVREQSVYCEIHPYNMALEKIKAFAPKGIILSGGPSSVYDKDAPHSDLGIYDLGV
PVLGICYGMQLMTQQLGGRVERCDKREFGRATLALDGKSEIFAGFDGGAEVWMSHGDRIEAMPAGFQLMAHTEGCPVAAM
KDEKRNFFGVQFHPEVVHTPRGEEMIGNFLFNVCGSQPTWTMANFIETELASIREKVGTGKVLCALSGGVDSAVVAVLIH
KAIGDQLHCVFVNNGLLRKGEADKVVNLFTKHFKINLTHVDAADRFLGMLEGISDPEQKRKIIGNEFIYLFEEEAKKLGQ
VDYLAQGTLYPDVIESVSTKGPSAVIKSHHNVGGLPEKMNLKLLEPVRELFKDEVRLLGKELGMPDEVVYRQPFPGPGLA
IRCIGELSAEKLDILRDADAIVIEEIRKAGLYREIWQSFAVLLPVKTVGVMGDARTYEWTVALRAVNSLDGMTADWVKLP
YELLGSISSRIINEVKGVNRVVYDISQKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-152 58
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-152 58
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 3e-152 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-130 52