Gene Information

Name : leuS (GM21_0766)
Accession : YP_003020598.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 913253 - 915727 bp
Length : 2475 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGAAGAGAAATACAACCCCTCAGCGGTTGAGGAGAAATGGCAGGGTTACTGGGCCGAACACGAGAGCTTCAAGGCGAC
CGAGGACCCCACCCGGAAGAAGTACTACCTGTTGGAGATGTTCCCGTACCCCTCGGGGAAGATCCACATGGGTCACGTCA
GGAACTATTCCATCGGCGACGTCATAGCGCGCTTCAAGAGGATGCAGGGGTACAACGTGCTGCACCCGATGGGGTGGGAC
GCCTTCGGCATGCCGGCGGAGAACGCGGCGATTCAGCACAAGAGCCATCCCGCCAAGTGGACCTACGAGAACATCGCCTA
CATGCGCGGCCAGCTGAAAACGCTTGGGCTTTCCTATGACTGGGACCGCGAGCTCGCCACCTGCGACCTCGACTATTACA
AGTGGGAACAGCGCATCTTCCTGGAGATGTACAAGAAGGGGCTCGCCTACAAGAAATCCTCCGCCGTCAACTGGTGCCCC
AAGTGCGAGACGGTGCTCGCCAACGAGCAGGTCGAGGACGGCTGCTGCTGGCGCTGCGATTCGCCGGTCCGGCAAAAAGA
GCTGGAGCAGTGGTCCTTCAGGATCACCAACTACGCGCAGGAACTCCTCGACGATACCTATAAGCTGACCGGCTGGCCGG
AGCGGGTTCTCACCATGCAGAGGAACTGGATCGGGCGCTCCACCGGCTGCGAGATCGACTTCCCGCTGGAGAACGGGCTC
GGGAAAATCAAGGTGTTCACCACCAGGCAGGACACCCTTTTCGGCGCCACCTTCATGTCCCTTGCCGCCGAGCACCCCAT
GGCGCTCGACTTGGCCGGCGACGCCCAGCGCGCCCAAGTCGAGGCCTTCATCGACAAGGTGAAGAAGACCGACCGCATCA
AGCGGGGGGCGGAAGACCTGGAGAAGGAAGGGGTCTTCACCGGCTCCTACTGCGTCAACCCCGTCACCAACACGAAGATG
CCGATCTACCTCGCCAACTTCGTGCTGATGGATTACGGCACCGGCGCCGTCATGGCGGTACCGACCCACGACCAGCGCGA
CTTCGAGTTCGCCAAGAAATACAACCTACCGCTCAAGGTGGTGATCCAGCCCGAAGGGGAGACCCTGGATCCCGCGGCCA
TGACCGAGGCCTACACCGCCGAAGGGATCATGGCCAACTCCGGCCGCTTCGACGGCATGGGCAACGGCGACGCCAAGGAG
GCCATCGCCGACTTCCTGGAGAAAGAAGGGATCGGCAAGAAGACGGTCAACTTCCGCCTGCGCGACTGGGGCATCTCGCG
CCAGCGTTACTGGGGCAATCCCATCCCGGTGATCAACTGCGACCTCTGCGGCGTGGTGGCGGTCCCCGAGGCCGACCTCC
CGGTCGTGCTTCCCATGGACGCCGAGTTCACCGGCGAGGGGGGGAACCCGCTGGCCCGCGTGGACAGCTTCACCACCTGC
ACCTGCCCGCAGTGCGGCGAGGCCGCGCGTCGCGAGACCGATACCATGGACACCTTCGTGCAGTCCTCCTGGTACTTCCT
GCGCTACTGCTCGCCGAAGTTCTCGGCGGGCCCCCTGGACCGGGAAAAGGTCGAGGCCTGGATGCCGGTGGACCAGTACA
TCGGCGGCATCGAGCATGCCGTGTTGCACCTGCTCTACGCCCGCTTCTTCACCAAGGTGCTCAGGGACTTGGGCTACTGC
AACGTGGACGAGCCGTTCTCCAACCTCCTCACCCAGGGGATGGTGATCAAGGACGGCGCCAAGATGAGCAAGTCCAAGGG
GAACGTGGTCGACCCCAACGCCCTCATCGAGCGCTACGGCGCCGATACCGCGCGCCTTTTCTCGCTCTTCGCCGCTCCCC
CCGAGAAGGATCTGGACTGGAGCGACCAGGGGGTCGACGGGAGCTACCGCTTCCTGAACCGCGTCTGGCGCCTGGTTTAC
GACGTGCTCCCGGTGATCGGGGAGGCGGGCGCCGTCAATCCGGATAGCCTCGGCGCCGAAGCCAAGAAACTCAGGCGCGC
CGTGCACAAGACCATCAAGAAGGTGAGCGAGGACGTCGAAGAGCGTTTCCACTTCAACACCGCGATCGCCGCCGTGATGG
AACTGGTCAACGCCATCCAGGCCTTTGCCGCCAAGGACGCGCCGGAGAACGTCGCCGTGGTGCGCGAGGCGGTGGAATCG
GTGGTGCGCCTCCTGGCCCCCTTCGTGCCGCACTTCGCCGAGGAGCTCTGGTCTCAGTTGGGGCACGACACCGTACTGGA
AGCAGCAGGCTGGCCCGGCTACGACGCTGCCGCCGTGGTCGACGAAGAGGTGACCGTGGTGATCCAGGTGAACGGCAAGC
TGAGAAGCAAGCTGACCGTCGCCCCCGACGCCAAGGAAGAAGAGGTCAGAGCCCAGGCCTTGGCCGACGACAAGATCAAG
CCCTATCTCGAAGGGAAGGACGTCAAGAAGGTCGTCTACGTCCCCGGCAAGCTGGTGAGCATTGTCGTCGCGTAA

Protein sequence :
MEEKYNPSAVEEKWQGYWAEHESFKATEDPTRKKYYLLEMFPYPSGKIHMGHVRNYSIGDVIARFKRMQGYNVLHPMGWD
AFGMPAENAAIQHKSHPAKWTYENIAYMRGQLKTLGLSYDWDRELATCDLDYYKWEQRIFLEMYKKGLAYKKSSAVNWCP
KCETVLANEQVEDGCCWRCDSPVRQKELEQWSFRITNYAQELLDDTYKLTGWPERVLTMQRNWIGRSTGCEIDFPLENGL
GKIKVFTTRQDTLFGATFMSLAAEHPMALDLAGDAQRAQVEAFIDKVKKTDRIKRGAEDLEKEGVFTGSYCVNPVTNTKM
PIYLANFVLMDYGTGAVMAVPTHDQRDFEFAKKYNLPLKVVIQPEGETLDPAAMTEAYTAEGIMANSGRFDGMGNGDAKE
AIADFLEKEGIGKKTVNFRLRDWGISRQRYWGNPIPVINCDLCGVVAVPEADLPVVLPMDAEFTGEGGNPLARVDSFTTC
TCPQCGEAARRETDTMDTFVQSSWYFLRYCSPKFSAGPLDREKVEAWMPVDQYIGGIEHAVLHLLYARFFTKVLRDLGYC
NVDEPFSNLLTQGMVIKDGAKMSKSKGNVVDPNALIERYGADTARLFSLFAAPPEKDLDWSDQGVDGSYRFLNRVWRLVY
DVLPVIGEAGAVNPDSLGAEAKKLRRAVHKTIKKVSEDVEERFHFNTAIAAVMELVNAIQAFAAKDAPENVAVVREAVES
VVRLLAPFVPHFAEELWSQLGHDTVLEAAGWPGYDAAAVVDEEVTVVIQVNGKLRSKLTVAPDAKEEEVRAQALADDKIK
PYLEGKDVKKVVYVPGKLVSIVVA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 5e-159 43