Gene Information

Name : hemC (GM21_0408)
Accession : YP_003020247.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 482766 - 483722 bp
Length : 957 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGCGCTGAAAGAGCTGAGAATAGGTACCCGCGCGAGCCAGCTCGCACTCTGGCAGGCAAACTGGGTCAAATCCGAGCT
GGAAAAACGCTACCCGGACATGACCGTCACCCTCACCAAGATCAAGACCATCGGGGACAAGATCCTCGACGTGCCCCTGG
CTCAGGTGGGCGGCAAGGGCCTGTTCGTGAAGGAGATCGAGGAGGCGATGCTGCGCGGCGAGATCGACATCGCGGTGCAC
AGCATGAAGGACGTGCCGACCGAATTCCCCGAGGGGCTCGGCCTTTACTGCATCACCGAGCGTGAAGATCCGCGTGATGC
CGTCATCTCCAACAACGTGAAGTTCGCCGACCTGCCGCAGGGCGCGCGCATCGGCACCTCGGCGCTCAGGCGCCAGGCGC
AGCTTCTCAAGGTGCGTCCCGACCTCGAGATGGTCATCATCCGCGGCAACGTGCAGACCCGCATGGACAAGCTTAAGACC
GAAGGGCTGGATGCCGTCATCCTCGCCGCGGCCGGCCTGAACCGCCTGGGCTTTGCCGATCAGATCACCGAGCTGCTGCC
GACCGATCTCTCCCTCCCCGCCATCGGCCAGGGGGCGCTGGGCATCGAGTGCAACCTCTCCAACCAGGATGTGAAGGACG
CCATCTCCTTCTTCAACCACCCCGATACCAGCCGCGCTGTCCGCGCCGAGCGCGCCCTCTTGTGGCGCTGCGAGGGCGGC
TGCCAGGTTCCCATCGCCGCCTTCGGCGAAGTGACCGGCGACGAATTGAAGCTGACCGGTTTCATCGCCTCCGTCGACGG
CAAGGTTTCCGTCAAGGGAGTCGTGACGGGGCCTGCCGACGACTGCGAGAAGCTGGGCGTGAAGCTCGCCGAGCAGCTCC
TCTCCGAAGGTGGCCACGCCATCCTCGCCGAGGTGTACCAGCGTGAAGTCTCCAGGGAGAAGGAAATCCCGGTATAA

Protein sequence :
MALKELRIGTRASQLALWQANWVKSELEKRYPDMTVTLTKIKTIGDKILDVPLAQVGGKGLFVKEIEEAMLRGEIDIAVH
SMKDVPTEFPEGLGLYCITEREDPRDAVISNNVKFADLPQGARIGTSALRRQAQLLKVRPDLEMVIIRGNVQTRMDKLKT
EGLDAVILAAAGLNRLGFADQITELLPTDLSLPAIGQGALGIECNLSNQDVKDAISFFNHPDTSRAVRAERALLWRCEGG
CQVPIAAFGEVTGDELKLTGFIASVDGKVSVKGVVTGPADDCEKLGVKLAEQLLSEGGHAILAEVYQREVSREKEIPV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-65 53
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-65 53