Gene Information

Name : GM21_2614 (GM21_2614)
Accession : YP_003022410.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3051205 - 3051963 bp
Length : 759 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAAAATAACCGCGGTAATACCCGCCAGGTATGCTTCCACGCGTTTTGAGGGGAAGGCCTTGGCGGACATCATGGGGCG
CCCCATGGTGCAGCATGTTTACGAGCGCGCGGCGAAGGCGACGCTCGTGTCAGAGGTGATAGTCGCGACCGACGACGAGC
GGATAGCCGCCGCCGTGCGCGCCTTCGGCGGGAGGGTCGAGATGACCTCGCCGACCCACGAGACCGGGACCGACCGCCTC
GCCGAGGTGGCCGCCAAGATCGATGCGGACATCGTCGTGAACGTCCAGGGGGACGAGCCGCTGATAGATCCCGCCATGAT
CGACGAGGCGATCCGGCCGCTTTTGGACGATCCCTCCATCCCGATGGCCACCTTGAAATGCAGGATCAAGACGCTGCACG
ACTTCCTTTCCCCGAACGTGGTCAAGGTCGTTTCCGACCCCACCGGGAACGTGCTCTACTTCTCGCGTTCGCCGCTCCCC
TTTTTCAGGGACAAGTGGAACGATTTGAAGGACGACGCCTTCGTCTCCGGCAAGCTTCTCTGCTACAAGCACGTAGGTCT
CTACGTCTACCGCAGGGAATTTCTCCCCGTGTTCGCGGGGCTAAAGCCGACCTACCTCGAGCTCGCCGAGAAGCTCGAGC
AGTTGCGGGTTCTGGAAAACGGCTACCGCATCAAGATCGTCGAGACCGAGTTCGAGTCCATCGGCGTCGACACCCCGGCG
GACCTGGACAAGGTGCTTGAAAGGCTAAAAGACAGATAA

Protein sequence :
MKITAVIPARYASTRFEGKALADIMGRPMVQHVYERAAKATLVSEVIVATDDERIAAAVRAFGGRVEMTSPTHETGTDRL
AEVAAKIDADIVVNVQGDEPLIDPAMIDEAIRPLLDDPSIPMATLKCRIKTLHDFLSPNVVKVVSDPTGNVLYFSRSPLP
FFRDKWNDLKDDAFVSGKLLCYKHVGLYVYRREFLPVFAGLKPTYLELAEKLEQLRVLENGYRIKIVETEFESIGVDTPA
DLDKVLERLKDR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-47 48
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-47 48
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-47 48
unnamed AAK15335.1 unknown Not tested Not named Protein 7e-30 41