Gene Information

Name : GM21_2494 (GM21_2494)
Accession : YP_003022294.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Virulence
Product : nucleotide sugar dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0677
EC number : -
Position : 2917252 - 2918538 bp
Length : 1287 bp
Strand : -
Note : TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; KEGG: gbm:Gbem_1754 nucleotide sugar dehydrogenase

DNA sequence :
ATGACGCATAATCGTAAAATTTCAGTGGTAGGGCTTGGGTACGTTGGGCTTCCGGTGGCGGTCGCCTTCGGCAGGGTGCA
GCGAACCATCGGGTTTGACATCAGTGCGAAGAGGATCGAGGAGTTGCGCTCAGGATGGGACCGTACAGGGGAAGTTTCCT
CCGAGGATTTGGTCAGCGCCGACATCTGCTTCACCGACAAGATCGACGAGCTGGCACGGGCGGATTTTCATGTGGTGGCG
GTGCCGACACCTGTCGACTCGGCTAACCAGCCGGACCTCTCCCTGCTCTGCAGCGCATCGGAAACGGTGGGGAGGGCGCT
CAAAAAGGGTGACATCGTGGTCTACGAGTCCACGGTGTATCCGGGCGTCACAGAGGAGGTCTGCCTCCCCATCCTGGAGT
CGGTATCGGGGCTGAAGAGTCTCGATGATTTCACGGTCGGCTACAGCCCGGAGCGGATCAACCCAGGCGACAAGGAGCAC
ACCTTCACCAGCATCCTCAAGGTCGTTTCCGGTCAGGACCGGCACACCTTGGAGCAGGTGGACGCTGTGTACTCCTCGGT
GGTGAAGCCGGGGGTGCACCGTGCTCCTTCCATCAAGGTAGCCGAGGCCGCCAAGGTCATCGAGAACACCCAGCGCGACC
TGAACATCGCCCTCATGAACGAGCTGGCGCTGATTTTCGATCGCTTGGGGATCGATACCAGCGAGGTACTGGCCGCGGCG
GGAAGCAAGTGGAACTTCCTGAACTTCAAGCCGGGGCTGGTAGGCGGCCACTGTATCGGCGTCGATCCATACTATCTCAC
CTACCAGGCCGAGAAGATCGGGTACATCCCCCAGGTTATCCTGGCGGGGCGGCGCATAAACGACGGCATGGGTAAATTCA
TCGCCCAGCGGGCGGTAAAGGAGATCATCAGAGCGGGGCACCACGTGCTTGGCTCGTATGTTACGGTGCTGGGACTGACC
TTCAAGGAAAATTGCCCCGACCTGCGCAACTCGAAGGTCGTCGATATCTTGACCGAGCTCAGTGACTATGGATTGAAGGT
GCAGGTATGCGACCCGATAGCAGACCCCGCGGAGGCGCAGCAGGCGTACGGGGTAACGCTCAAGGAGCCGGAAAAACTCC
ATCCCGCGGTTGCTGTTATCGCCGCGGTCGCCCACGACTCCTACCGCGCCTGGGGGGCCGCAAAGTTCGCGAGCCTTATG
GTAGAGAACCCGGTGCTCATAGACGTGAAGGGTATTTACGACAGCCGGGCCATGTCTGCGGCGGGGATCCGGGTCTGGTG
CCTGTAG

Protein sequence :
MTHNRKISVVGLGYVGLPVAVAFGRVQRTIGFDISAKRIEELRSGWDRTGEVSSEDLVSADICFTDKIDELARADFHVVA
VPTPVDSANQPDLSLLCSASETVGRALKKGDIVVYESTVYPGVTEEVCLPILESVSGLKSLDDFTVGYSPERINPGDKEH
TFTSILKVVSGQDRHTLEQVDAVYSSVVKPGVHRAPSIKVAEAAKVIENTQRDLNIALMNELALIFDRLGIDTSEVLAAA
GSKWNFLNFKPGLVGGHCIGVDPYYLTYQAEKIGYIPQVILAGRRINDGMGKFIAQRAVKEIIRAGHHVLGSYVTVLGLT
FKENCPDLRNSKVVDILTELSDYGLKVQVCDPIADPAEAQQAYGVTLKEPEKLHPAVAVIAAVAHDSYRAWGAAKFASLM
VENPVLIDVKGIYDSRAMSAAGIRVWCL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1L AAA64651.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 9e-116 59
tviB NP_458740.1 Vi polysaccharide biosynthesis protein, UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-98 53
tviB NP_807945.1 VI polysaccharide biosynthesis UDP-glucose/GDP-mannose dehydrogenase Virulence SPI-7 Protein 1e-98 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GM21_2494 YP_003022294.1 nucleotide sugar dehydrogenase VFG0431 Protein 4e-99 53