Gene Information

Name : GM21_2009 (GM21_2009)
Accession : YP_003021819.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 2329899 - 2331047 bp
Length : 1149 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: gbm:Gbem_2218 Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence :
ATGAAGATCGCAACCGAAGCAGCACAGATAGGCCTGCAGCGCGACACCCGCACCGGTGCGGTGACCGTCCCCATCTATCA
GACCGCCACCTTCCGCCACCCTGGGCTTGGGCAAAGCACCGGCTACGACTACAGCAGGTCGGGAAACCCGACGCGCCAGG
CGTTAGAGGAAGGGCTCGCGGTGCTGGAGGGAGGGTGCCGCGGCTTCGCCTACGCCTCGGGGATGGCCGCCATCACGAGC
CTCATGTTCCTCTTCAAGCAGGGGGACCACCTGATAGTGACCGAGGACCTCTACGGCGGGAGCTATAGGCTCTTCGAGAA
GTTGTTCCAGCAGTTCGGGCTCAGCTTCAGCTACGTCGATACGAGCGATATCGAGCTGGTGCGCCAGGCCGTGAGGCCCA
ACACCCGCGCGCTCTTCGTGGAGTCGCTCACCAACCCGCTTTTGAAGGTGGCCGACATTGAGCGACTGGCGGCCCTGTGC
AAAGAGCGCGAGATGCTCTGCATCGTGGACAACACCTTCCTGACCCCGTATCTCTTGCGCTGTCTCGACCTGGGCGCCGA
CATCACCGTCTATTCAGGGAGCAAGTACCTGGCCGGCCACAACGACACCGTCTGCGGCCTGGTGGCGGTGAAGGACCCGG
CGCTCGCCGAGCAGGTCTACTTCCACCAAAACGGCGCCGGCGCGGTCCTGGGCCCGCAGGATTCCTGGCTCACCGTCAGG
GGGATCAAGACCCTCACCATCCGCATGGACCGGCAGCAGGAAAACGCCCTTGCCATAGCTAACTGGCTGAGCCTCCACCC
GCAGGTGGTAAAGGTGCATTATCCCGGCCTTCCCGATCACCCCGGGCACGAACTGATGAAACAGCGCGGCAAAGGTTTCG
GCGCCATGATTGCCTTCGAGGTGACCGAGCCGCACCTGGTCGACACGCTGCTGATGAAGACCCGCCTGATCTCCTTCGCC
GAGAGCCTGGGCGGGGTCGAGAGCCTGATCACCTTCCCCGCGGTGCAGACCCACGCGGACATCGAGCCGGAGACGCTGAA
GCGGCTCGGCATCAACCATTCACTACTCCGCCTTTCGGTGGGGATAGAAGACAAGGACGACCTGATCGCCGACCTGGCGC
AGGCGTTCGCAGGAGGAGAACCGCAATGA

Protein sequence :
MKIATEAAQIGLQRDTRTGAVTVPIYQTATFRHPGLGQSTGYDYSRSGNPTRQALEEGLAVLEGGCRGFAYASGMAAITS
LMFLFKQGDHLIVTEDLYGGSYRLFEKLFQQFGLSFSYVDTSDIELVRQAVRPNTRALFVESLTNPLLKVADIERLAALC
KEREMLCIVDNTFLTPYLLRCLDLGADITVYSGSKYLAGHNDTVCGLVAVKDPALAEQVYFHQNGAGAVLGPQDSWLTVR
GIKTLTIRMDRQQENALAIANWLSLHPQVVKVHYPGLPDHPGHELMKQRGKGFGAMIAFEVTEPHLVDTLLMKTRLISFA
ESLGGVESLITFPAVQTHADIEPETLKRLGINHSLLRLSVGIEDKDDLIADLAQAFAGGEPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-81 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-83 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-63 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GM21_2009 YP_003021819.1 cystathionine gamma-lyase BAC0207 Protein 2e-54 42