Gene Information

Name : GM21_2008 (GM21_2008)
Accession : YP_003021818.1
Strain : Geobacter sp. M21
Genome accession: NC_012918
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 2328769 - 2329902 bp
Length : 1134 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: gbm:Gbem_2219 Cys/Met metabolism pyridoxal-phosphate-dependent protein

DNA sequence :
ATGAAATTCGCGACCGAACTGATACACGGCGGAGCCCCAATAGACCCGGAGCACGGCTCCCTGAGCCACCCCATCTACCT
GAGTTCCACCTTCGCCCAGCGCTCCATGGAGCACTTCGGAAAGTACGACTACTCCCGCTCGGGGAACCCGACCCGCGAGG
CGCTCGAAGAGGCGGTGGCCGGGCTTGAGAAAGGCGCCGTCGGCCTTGCCTTCGCCTCAGGGATGGCAGCCATCTCCTCC
ACCTTGCTCATCTTCGCGCCCGGCGATCACCTGGTCGTCTGCGAGGACGTCTACGGCGGAACCTTCCGCGCCTTGACCAC
CGTATTGAACGGATGGGGACTGAACGCCACCTTCGTGGACGCGACCGATACGGCCGCCATAGCCGCAGCCATCAGGCCCG
AGACCAAGGCGCTCTACCTGGAGACCCCCTCCAACCCGCTCATCAAGATAACCGATCTGAGGAAAGCCGCGGCGCTCGCC
AAGGAGAAGGGGATCCTCACCATCGTCGACAACACCTTCATGACGCCGTACCTGCAGCGTCCGCTGGAATTGGGTTGCGA
CATCGTGCTCCACAGCGGCACCAAGTTCCTGAACGGCCACTCCGACGTCCTCTGCGGCTTCGCCGTCGCCAAGGACCCGG
CAGTAGGCCAAAGAATCCGCTTCATCCAGAACGCCTTCGGCGCAGTACTCGGGCCGCAGGACTGCTGGTTGGTCTTGCGC
GGGCTGAAGACCCTGAAAGTGCGCATGGAAGAGCACCAGGCAAGCGCCAAGGTGATCGTCTCCTGGCTCAAGGAGCAAAA
AGAGGTGGCGAAGATCTACTACCCCGGGCTCCCCGAGCACCCGGGCTACGAGATCAACAACGCGCAGTCCGCAGGCCCCG
GCGCCGTGCTCTCCTTCGAGCTGTCCAGCTACGAAGTGACCAGGAAGCTCCTGGAAGGGGTGAAGCTCTCCGCATTCGCC
GTCAGCCTGGGAGGGGTGGAAAGCATCCTCTCCTACCCCGCCAAGATGTCGCACGCCGCCATGCCCCCCGCCGAACGCGA
GGCCAGGGGGATCAAGGACACGCTGGTGCGTCTGTCGGTAGGCCTGGAAGATCCCGAGGACTTGATCGCCGACATGGAAA
GCTTCCTCAGATAA

Protein sequence :
MKFATELIHGGAPIDPEHGSLSHPIYLSSTFAQRSMEHFGKYDYSRSGNPTREALEEAVAGLEKGAVGLAFASGMAAISS
TLLIFAPGDHLVVCEDVYGGTFRALTTVLNGWGLNATFVDATDTAAIAAAIRPETKALYLETPSNPLIKITDLRKAAALA
KEKGILTIVDNTFMTPYLQRPLELGCDIVLHSGTKFLNGHSDVLCGFAVAKDPAVGQRIRFIQNAFGAVLGPQDCWLVLR
GLKTLKVRMEEHQASAKVIVSWLKEQKEVAKIYYPGLPEHPGYEINNAQSAGPGAVLSFELSSYEVTRKLLEGVKLSAFA
VSLGGVESILSYPAKMSHAAMPPAEREARGIKDTLVRLSVGLEDPEDLIADMESFLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-82 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-83 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-69 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GM21_2008 YP_003021818.1 cystathionine gamma-lyase BAC0207 Protein 4e-60 42