Gene Information

Name : PC1_2208 (PC1_2208)
Accession : YP_003017783.1
Strain : Pectobacterium carotovorum PC1
Genome accession: NC_012917
Putative virulence/resistance : Virulence
Product : type III secretion apparatus H+-transporting two-sector ATPase
Function : -
COG functional category : N : Cell motility
COG ID : COG1157
EC number : 3.6.3.14
Position : 2539080 - 2540447 bp
Length : 1368 bp
Strand : +
Note : KEGG: eca:ECA2083 type III secretion protein; TIGRFAM: type III secretion apparatus H+-transporting two-sector ATPase; ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alp

DNA sequence :
ATGCAGACACAACCTTCTTCTTTCCCCCTGCTCGATCAGTGGGTCGCACGGCAGCGCCAGCATTTGGCAGGCTTTGCGCC
CGTGGAGAAAAAAGGCCGCGTCATGGCCGTCAGCGGCATCTTGCTGGAGTGCAGTCTGCCGCAGGCGCGCATTGGCGACC
TGTGCTGGGTGGCACGCCAGGACGACAGCCAGATGATGGCCGAAGTCGTAGGGTTTAGCCCAGACAATACCTTTCTCTCC
GCGCTCGGGGCGCTGGACGGCATCGCTCAGGGTGCCACCGTGACGCCGCTGTATCAGCCGCACTGCATTCAGGTGTCGGA
ACGTTTGCTGGGCAGCGTGCTGGACGGGTTTGGGCGGGCGCTGGAGGACGATGGTGAGAGCGCGTTTGTCGAACCCGGTC
ATGCTACAGGTCGCACGCAGCCGGTGCTGGGCGATGCCCCGCCGCCGACCTCCCGACCGCGCATCAGCCAGCCGCTCCCC
ACAGGATTGCGCGCCGTCGATGGCTTGCTAACCATCGGTCAGGGGCAACGCGTCGGCATCTTCGCCGGCGCGGGCTGCGG
CAAAACCACGCTACTGGCCGAACTGGCACGTAATACGCCGTGCGACGCCATTGTTTTCGGGCTGATTGGCGAACGTGGCC
GCGAACTGCGCGAGTTTCTCGATCATGAACTGGACGATGAACTGCGCAGTCGCACCGTGCTGGTGTGTTCCACCTCCGAC
CGCAGCAGCATGGAACGCGCGCGCGCGGCGTTCACTGCCACGGCTATCGCCGAGGCTTACCGCGCCGAAGGCCGTCAGGT
ACTGCTGATTATTGATTCCCTGACGCGTTTCGCTCGTGCCCAGCGCGAAATCGGTCTGGCGCTCGGAGAGCCGCAGGGGC
GCGGCGGACTGCCGCCGTCGGTCTATACGCTACTGCCGCGGTTGGTTGAACGCGCTGGACAAACGGAAGACGGCGCCATC
ACCGCGCTCTATTCCGTGCTGATTGAACAGGATTCCATGAACGATCCGGTCGCCGACGAAGTCCGTTCATTGATTGACGG
ACACATCGTGCTCGCCCGACGCCTGGCGGAACAGGGGCATTATCCGGCTATCGACGTACTGGCCAGCCTGAGCCGCACCA
TGAGTAACGTCGTAGATACCGATCACACCCGCAACGCGGGCGGCGTACGGCGTCTGATGGCGGCGTACAAACAGGTTGAG
ATGCTAATTCGCCTCGGCGAATACCAGCCCGGCCATGATGTGCTGACCGATTCCGCCGTCAACGCCCATGCAGAAATCAC
GCAGTTTCTTCGTCAGTCAATGCGTGAACCGATGCCTTATGGCGTGATTCAGCAACAGCTCGCCGGAGTCAGCCGCTATG
CCCCATAA

Protein sequence :
MQTQPSSFPLLDQWVARQRQHLAGFAPVEKKGRVMAVSGILLECSLPQARIGDLCWVARQDDSQMMAEVVGFSPDNTFLS
ALGALDGIAQGATVTPLYQPHCIQVSERLLGSVLDGFGRALEDDGESAFVEPGHATGRTQPVLGDAPPPTSRPRISQPLP
TGLRAVDGLLTIGQGQRVGIFAGAGCGKTTLLAELARNTPCDAIVFGLIGERGRELREFLDHELDDELRSRTVLVCSTSD
RSSMERARAAFTATAIAEAYRAEGRQVLLIIDSLTRFARAQREIGLALGEPQGRGGLPPSVYTLLPRLVERAGQTEDGAI
TALYSVLIEQDSMNDPVADEVRSLIDGHIVLARRLAEQGHYPAIDVLASLSRTMSNVVDTDHTRNAGGVRRLMAAYKQVE
MLIRLGEYQPGHDVLTDSAVNAHAEITQFLRQSMREPMPYGVIQQQLAGVSRYAP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-155 78
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-141 71
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 9e-142 71
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 8e-142 71
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 1e-140 70
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 1e-119 69
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-121 68
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 2e-130 67
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-130 67
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 4e-127 66
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 2e-115 63
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 2e-115 63
lscN AAO18044.1 LscN Virulence TTSS locus Protein 7e-89 51
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 1e-85 49
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-85 49
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 1e-85 49
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 5e-77 49
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-77 49
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 4e-77 49
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 6e-77 49
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 6e-77 49
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 8e-86 48
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-85 48
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-84 48
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 5e-84 48
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-84 48
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 9e-85 48
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-79 48
escN AAC38383.1 EscN Virulence LEE Protein 4e-76 46
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-75 46
escN AAC31513.1 L0034 Virulence LEE Protein 3e-76 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 3e-76 46
escN NP_290268.1 hypothetical protein Virulence LEE Protein 4e-76 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 4e-76 46
unnamed AAL06369.1 EscN Virulence LEE Protein 1e-74 45
escN CAC81862.1 EscN protein Virulence LEE II Protein 4e-76 45
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 6e-76 45
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-76 45
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-76 45
escN AAK26715.1 EscN Virulence LEE Protein 5e-76 45
escN AAL57542.1 EscN Virulence LEE Protein 5e-76 45
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 4e-67 44
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-66 43
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 2e-66 43
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-66 43
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 2e-66 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 3e-64 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-75 42
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 9e-75 42
invC AAS66861.1 InvC Not tested SSR-2 Protein 8e-63 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0192 Protein 2e-93 52
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0048 Protein 1e-90 51
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0390 Protein 7e-88 49
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0515 Protein 2e-77 49
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2144 Protein 2e-86 46
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG1254 Protein 9e-74 46
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0812 Protein 1e-76 46
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0730 Protein 2e-76 46
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG0555 Protein 7e-67 43
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG1008 Protein 1e-63 42
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG1778 Protein 2e-64 42
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2459 Protein 2e-66 41
PC1_2208 YP_003017783.1 type III secretion apparatus H+-transporting two-sector ATPase VFG2331 Protein 2e-70 41