Gene Information

Name : thyA (Pjdr2_2655)
Accession : YP_003011395.1
Strain : Paenibacillus sp. JDR-2
Genome accession: NC_012914
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3074129 - 3075091 bp
Length : 963 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
GTGACAGTTCAAACGAGTGAAACGGAATATTTGCAATTGCTCCGGCATGTGCTTGAGAACGGCGTGAAGAAAGAGGACCG
GACGGGTACCGGAACGATCTCGACTTTCGGTTACCAGATGCGGTTTGACCTTGCCAAGGGCTTTCCGATTCTGACGACGA
AGAGAGTGCCTTTCAAGCTTATTGTCAGTGAATTGCTGTGGTTTATCAAAGGCGATAGCAATATCCGGTATTTGCTGAAG
CATAAGAACCATATTTGGGATGAATGGGCGTTTAAAAGATGGGTGGAGAGCACCGACTACAATGGCCCGGACATGACGAA
CTTTGGCCTTCGTTCGCAGACGGATGAGGCCTTCAACGTCGTATATCAAGAGCAGATGGACAAATTCACGAATCTCGTGC
TGACCGATGATGCTTTTGCCGAGAAGTACGGCGATCTGGGCAACGTTTACGGCAAGCAATGGCGTGAATGGCGTACAACG
CAAGGAGAAACGATTGATCAGCTCAAGGGAATTATCGATACGATCAAGAAAAATCCGGATTCCCGCCGTTTGATCGTATC
GGCATGGAACCCAGAGGACGTACCGTCGATGGCGCTTCCTCCTTGCCACACGATGTTCCAGTTTTATGTGATTAACGGCA
AGCTGAGCTGTCAGCTGTATCAGCGGAGCGGCGATATTTTCCTCGGAATCCCGTTTAATATTGCAAGCTATGCTCTGCTC
ACGCATCTCATTGCCCAGGAGTGCGGGCTTGGGGTCGGCGAGTTTATTCATACGCTTGGCGATGCGCATATTTATTTGAA
CCACCTGGAACAAATTGATATTCAATTGCAGCGGGACATGCGGGAGCTGCCAGTCCTTGCGATAAATCCGGATGTGAGTT
CAATCTTCGACGCGGAGGTTGAAGATATCAAGCTCGAGAACTATCAGCCGCATCCTACTATTAAGGCTCCGGTAGCCGTA
TAA

Protein sequence :
MTVQTSETEYLQLLRHVLENGVKKEDRTGTGTISTFGYQMRFDLAKGFPILTTKRVPFKLIVSELLWFIKGDSNIRYLLK
HKNHIWDEWAFKRWVESTDYNGPDMTNFGLRSQTDEAFNVVYQEQMDKFTNLVLTDDAFAEKYGDLGNVYGKQWREWRTT
QGETIDQLKGIIDTIKKNPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVINGKLSCQLYQRSGDIFLGIPFNIASYALL
THLIAQECGLGVGEFIHTLGDAHIYLNHLEQIDIQLQRDMRELPVLAINPDVSSIFDAEVEDIKLENYQPHPTIKAPVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_189147.1 thymidylate synthase Not tested ¥ÕSP¥â Protein 4e-104 66