Gene Information

Name : NT05HA_0961 (NT05HA_0961)
Accession : YP_003007423.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 982011 - 982784 bp
Length : 774 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGACCCAATTTACTGTTATTATTCCCGCTCGCTATGCTTCAAACCGTTTACCGGGAAAACCCTTAGCCGACATTGTCGG
CAAACCGATGATTCAACATGTTTTTGAACAAGCCAAACAATCAGGCGCAACCCGCGTGATTATCGCCACCGACAACGACC
TGGTGGCTGCCGCCGCCAAAAACTTTGGTGCAGAAGTGTGCATGACCGCAGAAAGCCACAATTCCGGTACGGAACGCTTA
GCTGAAGTGGTTGAAAAACTGGCGATTCCCGACAACGAAATCATCGTTAACATCCAAGGCGACGAACCCCTCATTCCGCC
AGCTATCGTAAAACAAGTGGCAGAAAATCTCTCTAAATACCCTGTCAACATGGCAAGCCTTGCGGTCAATATCGACGAGG
CTGAGGAATTATTTAATCCCAACGTGGTGAAAGTACTGACCGACAAAGACGGCTATGTGCTTTATTTCTCCCGCGCGGTG
ATTCCTTGGGATCGCGATCAATTTGCGCAAATGGATGACGTAGCAAAATTGCAACTGAACACACAATACTTACGCCATAT
TGGGATTTATGCTTATCGCGCCGGTTTCATTAAACAATATGTGCAATGGCAACCGACAGCATTAGAACACATCGAAAAAC
TGGAACAGCTACGCGTGCTTTGGAACGGTGAAAAAATTCATGTAGAACTCGCCAAAGAAGTGCCGGCTGTGGGCGTGGAT
ACAGCCGAAGATCTGGAAAAAGTGCGGTCGATTTTAGCGAAGAAATCGCATTAA

Protein sequence :
MTQFTVIIPARYASNRLPGKPLADIVGKPMIQHVFEQAKQSGATRVIIATDNDLVAAAAKNFGAEVCMTAESHNSGTERL
AEVVEKLAIPDNEIIVNIQGDEPLIPPAIVKQVAENLSKYPVNMASLAVNIDEAEELFNPNVVKVLTDKDGYVLYFSRAV
IPWDRDQFAQMDDVAKLQLNTQYLRHIGIYAYRAGFIKQYVQWQPTALEHIEKLEQLRVLWNGEKIHVELAKEVPAVGVD
TAEDLEKVRSILAKKSH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 5e-40 42
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-39 42
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 4e-40 42