Gene Information

Name : alr (NT05HA_0681)
Accession : YP_003007167.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : -
Position : 686887 - 687969 bp
Length : 1083 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCACATGAAACCCGCAACAGCCAAAATCAGTTCTGTTGCTTTAAAACACAATATTCAAACCATTAAACAAAAAGCACC
GAATAGCAAAATTATTGCGGTAGTCAAAGCCAATGCTTACGGACATGGTGTCGTATTTCTTTCTTCCGCCGTAGAAAGCT
TAGTCGATTGTTTTGGCGTGGCACGTTTGGAAGAGGCATTAAAATTGCGTTCCAACGGTATTACCAAGCCGATTTTGTTA
TTAGAAGGCTTTTTCTCTTCTAAAGATTTGCCGATTTTGGCGGTCAATAATATTCAAACTGTGGTACATAGCAAAGAACA
GCTAGAGGCTTTGGAAAGAGCGAAAACCCCAAATCCGGTAAAAGTGTGGTTAAAAATTGATACGGGAATGCATCGTTTAG
GCGTGCATTTGGATGAAGTTGAAACCTTCTACCAAAAATTAAAATCCCTCACTTGTGTCGATCCGAATATTGGTTTTGTG
AGCCACTTTAGTCGTGCGGATGAGCTGGAGTGCGGTTATACTGAGAAACAATTAGCCCGATTTTTACAGGCAACGGAAGG
TAAATCCGGTGAGCGTAGCATTTCCGCTTCCGGCGGTATTCTGTTTTGGCCGGAGGCGCATTTAGACTGGATTCGTCCCG
GCATTATTATGTACGGTATTTCACCGAATAACACCGCTGGAAAAGAATACGGTTTAACGCCGGTGATGAATTTAACCTCT
TCTTTAATTGCCGTGCGTGAACACAAGAAAGGCGAACCGGTGGGCTATGGCGGTGTATGGGTAAGTGATAAAGATACCAA
AATCGGCGTGGTAGCCATTGGTTATGGCGATGGCTATCCGCGTGATGTGCCGGAAGGCACTCCGGTTTATCTTAACGGCC
GTCGCGTACCGATTGTGGGCAAAGTGTCCATGGATATGTTGACGGTGGATCTCGGCGCAGACAGCCAAGATAAGGTGGGC
GATGAGGTAATTCTGTGGGGCAAAGAATTACCGATTGAAGAAATTGCGTCAATTGCCGGCATTATCAGCTATGAATTAAT
TACCAAATTAACCCCGCGTGTTTTAACCGAATACATTGATTAA

Protein sequence :
MHMKPATAKISSVALKHNIQTIKQKAPNSKIIAVVKANAYGHGVVFLSSAVESLVDCFGVARLEEALKLRSNGITKPILL
LEGFFSSKDLPILAVNNIQTVVHSKEQLEALERAKTPNPVKVWLKIDTGMHRLGVHLDEVETFYQKLKSLTCVDPNIGFV
SHFSRADELECGYTEKQLARFLQATEGKSGERSISASGGILFWPEAHLDWIRPGIIMYGISPNNTAGKEYGLTPVMNLTS
SLIAVREHKKGEPVGYGGVWVSDKDTKIGVVAIGYGDGYPRDVPEGTPVYLNGRRVPIVGKVSMDMLTVDLGADSQDKVG
DEVILWGKELPIEEIASIAGIISYELITKLTPRVLTEYID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 1e-60 45