Gene Information

Name : NT05HA_0546 (NT05HA_0546)
Accession : YP_003007046.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : -
Position : 548510 - 549394 bp
Length : 885 bp
Strand : +
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGCGTTGTTTAGCGTTAGATATCGGCGGAACCAAAATGGCGACCGCCATTGTGTCAGAGAACCAAGTGACACAGCGGAA
ACAAATTAGCACACCACAGGAAAATGTGGTGGAAGCAATGCATCAAACATTGGCACAATTATTGGCAGATTATGCCGCTC
AATTTGAGTATGTGGCGGTGGCTTCAACAGGTATTATTAATAAAGGAATATTAACCGCACTTAATCCGAAAAACTTAGGT
GGGTTGGCCTATTTTCCTTTAAAACAAAGCATTTCCAAACATACGTCCAAGCCGGTATTGTTATTAAATGACGCACAAGC
GGCAACTTATGCCGAATATCAACTGCAAGATAAAAATAACATTCAAAACTTTGCATTTATTACCGTCTCTACCGGCGTAG
GTGGCGGGTTAATTTTAAACCATCAGTTACTCACAGAACCGAATGGTATTGCCGGCCATATTGGGCATACTTTGGCCGAT
CCGAACGGGCCTGTGTGCGGTTGCGGGCGTGTAGGTTGCGTAGAAGCCATCGCATCAGGCCGTGCCATTGAAGCGGTTTC
CAAACAATGGGACGATCCTTGTGATCCCAAAGAAGTCTTTACCCGTTTCAGAAAAACGGATGAAAAAGCTACCGCACTTG
TGTCCCGTTCGGCAAAAGCCATTGCTAACCTAGTCGCGGATTTGGTTATTGGTATGGATGTACAAAAAGTGGTGCTAGGT
GGTAGCGTTGGATTGGCGGAAGGTTATTTACCTTTGGTGAACGAATATTTGGCAGAAATGCCGGAGATTTATCGTTGTCC
GTTGGATGCAGCACGATTAGGGCAAGATGCAGGTCTTATCGGTGCTGCTGCTTGGGCTCAGACACAATTAACTCACTTGG
AGTGA

Protein sequence : 
MRCLALDIGGTKMATAIVSENQVTQRKQISTPQENVVEAMHQTLAQLLADYAAQFEYVAVASTGIINKGILTALNPKNLG
GLAYFPLKQSISKHTSKPVLLLNDAQAATYAEYQLQDKNNIQNFAFITVSTGVGGGLILNHQLLTEPNGIAGHIGHTLAD
PNGPVCGCGRVGCVEAIASGRAIEAVSKQWDDPCDPKEVFTRFRKTDEKATALVSRSAKAIANLVADLVIGMDVQKVVLG
GSVGLAEGYLPLVNEYLAEMPEIYRCPLDAARLGQDAGLIGAAAWAQTQLTHLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 1e-35 47
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-29 42
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 3e-29 42
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 8e-29 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NT05HA_0546 YP_003007046.1 N-acetylmannosamine kinase VFG1115 Protein 1e-29 42