Gene Information

Name : leuS (NT05HA_2199)
Accession : YP_003008594.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 2153598 - 2156186 bp
Length : 2589 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCAAGAACAATATCGTCCTGATTTACTTGAACCGGAAGTGCAAAAATTCTGGCAGGACAATAAAACTTTTAAAGCAGT
ACAAGATAACAACAAAGAAAAATACTATTGTCTTTCCATGTTCCCTTATCCATCAGGCCGTTTGCATATGGGGCATGTGC
GTAATTACACCATCGGCGATGTGGTTTCCCGCTATCAACGTATGAAAGGAAAAAATGTGTTGCAACCTTTTGGTTGGGAC
GCTTTCGGTTTGCCGGCAGAAGGGGCGGCAGTGAAAAATAACACCGCTCCGGCTAAGTGGACGTATGAAAATATTGCCTA
TATGAAGAAACAACTTCAGATTTTAGGCTTTGGTTTCGACTGGGATCGTGAAATCGCTACGTGTAAACCGGAATATTATA
AATGGGAACAATGGTTTTTCACGGAGCTTTATAAAAAAGGCTTAGTGTATAAAAAAACCTCTACCGTGAACTGGTGTCCA
AATGATGAAACGGTGTTGGCGAACGAACAGGTGCACGAAGGTTGCTGCTGGCGTTGTGATACCCCGGTGGAACAAAAAGA
AATTCCACAATGGTTTATTAAAATCACTGATTACGCTGAGCAGTTGCTAAATTGCTTAGATGATTTACCACAATGGCCGG
ATCAAGTAAAAACCATGCAACGCAACTGGATCGGCCGTTCCGAAGGGGTAGAAATCACTTTTGATATTAAAGATACCAAT
GAAAAATTAGCGGTTTATACCACCCGTCCGGATACGTTCTACGGCGTGAGTTATGTAGCGGTGGCGGCTGCTCATCCACT
GGCAACGCTTGCGGCGCAAAATAATCCTGAATTAGCAGAGTTCATTCAAGAAGCGAAAAACACTAAAGTGGCGGAAGCGG
ACATTGCCACCATGGAGAAAAAAGGCATGCCGACAGGGCTTTATGCCATTCATCCGTTAACCGGTGAACAAGTGCCAGTG
TGGGTGGCGAACTTTGTGTTAATGCACTATGGTACCGGTGCGGTGATGGCCGTACCGGCGCACGATCAACGCGATTTTGA
ATTCGCGCAAAAATATCATTTACCGATTAAACAGGTTATCGAACCGATTAACGGCGAAGCGATCGATTTAACCAAACAAG
CTTTTACCGAACATGGCAAACTGGTTCACTCCGGCGAATTTGATGGGTTGGCATTTGACGCCGCGTTTAATGGCATCGCC
AATAAATTGGAGTCCATGGGCAAAGGCAAACGCCAAGTAAATTATCGCTTACGCGACTGGGGCGTTTCTCGTCAACGTTA
TTGGGGCGCTCCAATTCCGATGCTAACCTTGGAAAACGGTGATGTGGTGCCGGTGCCAATGGAAGATTTACCAATCATCC
TGCCGGAAGACGTGGTGATGAACGGTGTGAACAGCCCGATTAAAGCGGATCCTGAATGGGCGAAAACTACATATCTGGGC
AAACCTGCATCAAAAGAAACCGATACCTTCGATACTTTCATGGAATCTTCTTGGTACTACGCCCGCTATACCTGCCCGCA
ATATCAACAAGGCATGTTAAACAGCGAAGAGGCGAACTATTGGCTACCGGTGGATCAATATATCGGCGGTATCGAGCATG
CGACCATGCATTTATTGTATTTCCGCTTCTTCCATAAATTATTGCGTGATGCAGGCTTGGTAAATAGCGATGAACCGGCC
GATAAATTATTGTGTCAAGGTATGGTGTTAGCGGATGCTTTCTATTACACCAGCCCGACCAACGAGCGTATTTGGGTCTC
TCCGACTAAAGTCACATTGGAACGTGATGAAAAAGGTCGTATCGTGAAAGCTGTGGATGATGAAGGCCATGAATTGGTAC
ATGCCGGCATGACTAAAATGTCAAAATCCAAAAACAACGGTATTGACCCGCAAGAAATGGTGGAAAAATACGGCGCGGAC
ACCGTACGTTTATTTATGATGTTCGCCTCCCCCGCAGAAATGACTTTGGAATGGCAGGAGTCCGGTGTTGAAGGGGCAAA
ACGTTTCTTGGCTCGGGTGTGGAATTTGGTGTTTGAATACAACAAAAATCCGACAAAAACAGCTGTAAATCCGACCGCAC
TTTCAGCTTCACAAAAAGCCTTGCGTCGCGATGTTCACAAAACCATTGCGAAAGTGAGTGATGACATTGGTCGCCGTCAA
ACCTTCAATACCGCTATCGCTGCGGTCATGGAATTAATGAACAAATTGACCCGTGCGCCGTTGGATGACGAGCAAGATCG
CGCCATTATGGCGGAAGCGCTGAGCGCGGTAGTCAGAATGTTATATCCAATTACGCCGCATATTTGTTTCCGTTTGTGGC
AGGAATTGGGTAATCAAGATGCCATTGATTTTGCCCCATGGGTAGAAGCCGATGAGCAGGCCATGGTGGACGATGAAAAA
CTGATTGTGGTGCAAGTCAACGGCAAAGTGCGTGGCAAGGTCACCGTGGCGGCAGATGCTGATGAAGATACGGTGAAAAC
CATGGCCTTCGCCGATGAGAATGTAAAACGCTTCCTCGACGGTATGCAAGTGGTGAAAGTGATTTATGTGGCTGGTAAAT
TACTCAATGTTGTGGTGAAACCACAGTAA

Protein sequence :
MQEQYRPDLLEPEVQKFWQDNKTFKAVQDNNKEKYYCLSMFPYPSGRLHMGHVRNYTIGDVVSRYQRMKGKNVLQPFGWD
AFGLPAEGAAVKNNTAPAKWTYENIAYMKKQLQILGFGFDWDREIATCKPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP
NDETVLANEQVHEGCCWRCDTPVEQKEIPQWFIKITDYAEQLLNCLDDLPQWPDQVKTMQRNWIGRSEGVEITFDIKDTN
EKLAVYTTRPDTFYGVSYVAVAAAHPLATLAAQNNPELAEFIQEAKNTKVAEADIATMEKKGMPTGLYAIHPLTGEQVPV
WVANFVLMHYGTGAVMAVPAHDQRDFEFAQKYHLPIKQVIEPINGEAIDLTKQAFTEHGKLVHSGEFDGLAFDAAFNGIA
NKLESMGKGKRQVNYRLRDWGVSRQRYWGAPIPMLTLENGDVVPVPMEDLPIILPEDVVMNGVNSPIKADPEWAKTTYLG
KPASKETDTFDTFMESSWYYARYTCPQYQQGMLNSEEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGLVNSDEPA
DKLLCQGMVLADAFYYTSPTNERIWVSPTKVTLERDEKGRIVKAVDDEGHELVHAGMTKMSKSKNNGIDPQEMVEKYGAD
TVRLFMMFASPAEMTLEWQESGVEGAKRFLARVWNLVFEYNKNPTKTAVNPTALSASQKALRRDVHKTIAKVSDDIGRRQ
TFNTAIAAVMELMNKLTRAPLDDEQDRAIMAEALSAVVRMLYPITPHICFRLWQELGNQDAIDFAPWVEADEQAMVDDEK
LIVVQVNGKVRGKVTVAADADEDTVKTMAFADENVKRFLDGMQVVKVIYVAGKLLNVVVKPQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 6e-155 42