Gene Information

Name : murD (NT05HA_0216)
Accession : YP_003006741.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 208007 - 209323 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGCAATATCAAAATAAAAAAGTCACCGTGATCGGTTTAGGCAAGACGGGATTGTCTTGTGTGGATTTTTTACGTGCTAA
ACAGGCGGATGTGCGAGTGATTGATACCCGCCAACAGCCGGCAGGTGCCGATCAATTAAGCAAAGAAATTCCGTTGCATA
CGGGTAGCTTAAATCAACAATGGCTGTTGGAAAGCGATTTGATTGTTATCAGCCCGGGGCTTGCGGTAAAAACACCTGAA
ATTCAGACCGCACTTCAAGCGGGCGTCGAAGTGGTGGGTGACATTGAATTATTCTGCCGTGAAGCGGACAAACCGATTGT
GGCGATTACCGGTTCGAACGGCAAAAGCACGGTGACCACATTAGTCGCGGAGATGGCGAAAGCCGGCGGGTTAAGTGTGG
GGATGGGCGGTAACATCGGAATTCCTGCGCTTTCTTTGTTAAATCAACAACATGATTTGTATGTGTTAGAGCTTTCCAGT
TTTCAATTAGAAACCACTTATTCTCTCAAAGCCATGGCGGCAACGGTGTTAAATGTCACCGAAGATCACATGAACCGCTA
TGTCGATTTACAGGATTATCGCCACGCCAAACTCAAAATTTACGATAATTGTCAAACTGCCGTCATTAACGGGGAAGACG
CTTTAACGTTGCCGACAACACAACGTCCGCAACAACAAGTCTCTTTTGCGGAAAATAATGCGGATTATTGGTTAAAAACC
GATGGGCACCACACTTATTTAATGGCGTGTAATGAGTCCATTTTGACCATTGATGAAATGAAACTAAGCGGACGTCATAA
TTATATGAATGCATTGGCTGCGATAGCTTTAGCACAGGCTGCGGGTGTAAATTTATCGGGAATTCAGACCGCACTTCGTG
AGTTTGGTGGGTTGGATCATCGTTTCCAATTGGCGCACATGGCAGATGGTGTACGCTGGATTAACGATTCTAAAGCGACC
AATGTGGGAAGCACTGTTGCTGCCTTAACCGGTTTGCAGGTGAAGGGAAAATTGCATTTATTGCTTGGCGGTGATGGAAA
AGGCGCAGATTTTTCTGAATTGGCGACATTAATTAATCAACCGCATATTTTTTGTTATTGCTTTGGGCAGGATGGTAAAC
AGTTAGCCGCACTTTCGCCACAAAGCCAATTATTTGACACCATGGAACAAGCCATTGCGGCAATTCGTCTGCAGTTACAA
GCAGGGGACATGGTATTGTTATCTCCGGCGTGTGCCAGCTTAGATCAATTCCCTTGTTTTGAAGCGCGTGGTGACGAATT
TACGCGTTTGGCGCAATTAAGCTCGTCGTTAGGTTAG

Protein sequence :
MQYQNKKVTVIGLGKTGLSCVDFLRAKQADVRVIDTRQQPAGADQLSKEIPLHTGSLNQQWLLESDLIVISPGLAVKTPE
IQTALQAGVEVVGDIELFCREADKPIVAITGSNGKSTVTTLVAEMAKAGGLSVGMGGNIGIPALSLLNQQHDLYVLELSS
FQLETTYSLKAMAATVLNVTEDHMNRYVDLQDYRHAKLKIYDNCQTAVINGEDALTLPTTQRPQQQVSFAENNADYWLKT
DGHHTYLMACNESILTIDEMKLSGRHNYMNALAAIALAQAAGVNLSGIQTALREFGGLDHRFQLAHMADGVRWINDSKAT
NVGSTVAALTGLQVKGKLHLLLGGDGKGADFSELATLINQPHIFCYCFGQDGKQLAALSPQSQLFDTMEQAIAAIRLQLQ
AGDMVLLSPACASLDQFPCFEARGDEFTRLAQLSSSLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-51 41
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-51 41