Gene Information

Name : hemC (NT05HA_1600)
Accession : YP_003008024.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 1599315 - 1600241 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCTTGAAAAAACCTTGAAAATTGCTACCCGCCAAAGTCCGTTGGCGTTATGGCAAGCAAATTATGTGAAAGACTGTCT
GCAACAGTTATATCCCGATTTAATCGTCGAATTGGTGCCAATGGTGACAAAAGGCGATGTCATTTTGGATTCACCGCTGG
CAAAAATTGGTGGCAAAGGGTTATTTGTCAAAGAGTTAGAAAATGCCTTGTTAAATAAGGAAGCGGATATTGCCGTGCAC
TCCATGAAAGATGTACCGATGCAATTTCCCGAAGGGTTGGGATTAGCAGTAATTTGCAAACGTGAAGATCCGCGTGATGC
ATTTGTTTCTAATTCTTACCGCACTTTTGATGAGTTACCGCAAAGTGCGGTGGTCGGAACATCGAGTTTGCGTCGTCAAT
GTCAATTGAAAGCTTTACGCCCTGATTTGGATATTCGTTCTTTGCGCGGCAATGTGGGGACGCGTTTAAGTAAGTTAGAT
AACGGCGATTATGACGCGATTATTTTAGCTTCTGCCGGCCTCATTCGTTTAGGTTTGGCAGATCGTATCGCGTCTTTTAT
TGAAGTCGAACAATCTTTACCGGCGGCCGGGCAAGGCGCTGTGGGGATTGAATGTCGCACAGATGATGTGCAGGTAAAAC
AATTATTAGCACCGTTAGCTGATGCGGAAACCACTTGTTGTGTGCTGGCGGAGCGCGCCATGAACAATCATTTACAAGGT
GGTTGCCAAGTGCCGATTGGCGGTTATGCAGTGTTGCAACAGGGACAATTGTATTTAAGAGCCTTAGTAGGTAATGTTGA
CGGCTCACAAATTATTCGGGCGGAAGGCAAAAGTGCGGTGAAAAATGCGGACGTTTTAGGTGTGCAAATTGCCGAACAGC
TTTTGGCACAAGGTGCCGACAAAATTTTGCAGTCGATTTACTCATAG

Protein sequence :
MLEKTLKIATRQSPLALWQANYVKDCLQQLYPDLIVELVPMVTKGDVILDSPLAKIGGKGLFVKELENALLNKEADIAVH
SMKDVPMQFPEGLGLAVICKREDPRDAFVSNSYRTFDELPQSAVVGTSSLRRQCQLKALRPDLDIRSLRGNVGTRLSKLD
NGDYDAIILASAGLIRLGLADRIASFIEVEQSLPAAGQGAVGIECRTDDVQVKQLLAPLADAETTCCVLAERAMNNHLQG
GCQVPIGGYAVLQQGQLYLRALVGNVDGSQIIRAEGKSAVKNADVLGVQIAEQLLAQGADKILQSIYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-88 65
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-88 65