Gene Information

Name : NT05HA_1400 (NT05HA_1400)
Accession : YP_003007838.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 1407976 - 1409253 bp
Length : 1278 bp
Strand : -
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
TTGTTGAAAAAAAATGCAAAAAATTCAACTTTAAGAGACAAAAAATTTAATCCGTTTAATCAAGTATTTATAAAAATTTT
CTTTAATAGCACAAGGGTTTGTGCCAAAATGAGCCTCAATTTTTATAAAAAGTGCGGTATGAAATTTTGTTATTTTATCG
GAGGATGTATGACGCAAGAATATGAGATTGATACTTTATTAGCTCAAGCCGGTAATCGTTCAGATGAGCGAACCGGTGCG
GTTTCCACCCCTATTTTCCTTTCCACGGCCTACGGCCATCACGGAATTGGTGAAAGCACAGGTTTTGATTACACCAGAAC
TAAAAACCCAACCCGTAGCATATTAGAAGACACCATTGCCAAATTAGAAAAAGGTGAATGCGGATTTGCTTGTTCTTCCG
GTATGGCTGCAATTCAATTATTGATGTCATTATTTACTTCACCGGATGAATGGATCGTGTCCAGTGATGTGTATGGTGGC
ACTTATCGTTTATTGGATTTTTGTTATAAAAACACCAACGGCGTGAAACCGGTATATGTAAATACCGCCTCTGTAAATGA
AATTGAGGCAGCGATTACGCCGAATACCAAAGCCATTTTTATTGAGACGCCGTCTAATCCGTTAATGGAAGAATGCGATG
TGGATGCCATTGCGAAGGCAGCGAAAAAGCATAATTTATTACTCATTGTTGATAATACATTTTTAACACCGGTGTTATTC
CGCCCGATGGAGCATGGCGCGGATATTGTTATTCACAGCGGCACAAAATATATTGCTGGTCATAATGATGTGTTGGTTGG
TTTAATTGTTGCGAAAGGGCAGGAATTATGTGATCGTCTAGCTTATATTCAGAACGGTGCAGGTCCGGTGTTATCACCAT
TTGATTCTTGGCTAACCATTCGTGGCATGAAAACCTTAGCCTTACGTATGCAACGTCATGAAGAAAATGCGAAAGCCATT
GCGGAATTTTTAAAACAACAACCACAAGTTAAAGATGTGTTATATCCTAACAAAGGCGGGATGTTATCGTTCCGCTTACA
AGATGAAAACTGGGTGAATACTTTTTTAAAATCCATTAGATTGATTACCTTTGCTGAAAGCCTTGGTGGTACGGAAAGTT
TTATTACTTATCCGGCAACCCAAACCCACATGGATATTCCGGAAGCAGAACGTATTGCGCGCGGAATTACGAACAATCTG
TTACGTTTCTCTGTGGGGTTAGAAAATGTTGAGGACATTAAGGCTGATTTAGCACAAGCATTTGCACAACTGAAATAA

Protein sequence :
MLKKNAKNSTLRDKKFNPFNQVFIKIFFNSTRVCAKMSLNFYKKCGMKFCYFIGGCMTQEYEIDTLLAQAGNRSDERTGA
VSTPIFLSTAYGHHGIGESTGFDYTRTKNPTRSILEDTIAKLEKGECGFACSSGMAAIQLLMSLFTSPDEWIVSSDVYGG
TYRLLDFCYKNTNGVKPVYVNTASVNEIEAAITPNTKAIFIETPSNPLMEECDVDAIAKAAKKHNLLLIVDNTFLTPVLF
RPMEHGADIVIHSGTKYIAGHNDVLVGLIVAKGQELCDRLAYIQNGAGPVLSPFDSWLTIRGMKTLALRMQRHEENAKAI
AEFLKQQPQVKDVLYPNKGGMLSFRLQDENWVNTFLKSIRLITFAESLGGTESFITYPATQTHMDIPEAERIARGITNNL
LRFSVGLENVEDIKADLAQAFAQLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-66 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-67 42