Gene Information

Name : NT05HA_1289 (NT05HA_1289)
Accession : YP_003007733.1
Strain : Aggregatibacter aphrophilus NJ8700
Genome accession: NC_012913
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1296095 - 1297999 bp
Length : 1905 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGACTGTTTATAGCTGAAAAACCGAGTCTTGGACGTGCTATTGCCGATGTTTTGCCCAAGCCGCACCAACGTGGTGA
TGGCTTTATTAAATGCGGCGATAACGATTATGTCACTTGGTGCGTAGGGCATTTGTTGGAACAGGCAGAACCCGACGCTT
ACGACGCACGCTTCAAACAATGGCGCTTAGAGGATTTGCCTATCGTGCCGCAAAAGTGGCTACTCATTCCGAAAAAAGAA
ACCCATAAACAACTGAAAACCGTTGAAAAACTGGTACATCAAGCCGAGATATTGGTCAACGCAGGCGACCCGGATCGAGA
GGGGCAACTGTTGGTGGACGAGGTGTTCAGTTATCTCAATTTGCCTGCCGAGAAGCGTAATGCCATTCAACGTTGTTTAA
TCAGCGATTTGAACCCAAGTGCGGTAGAAAAAGCCATCAAAAAATTACAACCTAACCGAGATTTCATCCCGCTAGCCACC
TCCGCATTAGCCCGCGCCCGCGCCGATTGGCTTTATGGCATTAATATGACTCGCGCTTATACCATTCGAGGCAGACAGGC
TGGCTATAACGGCGTGCTTTCCGTTGGGCGTGTACAAACACCGGTGCTGGGTTTGATCGTACGTCGTGATTTGGAAATTG
AAAATTTCCAACCAAAAGATTTTTTTGAAGTGCTGGCTTGGGTTCGCGATCCGAAAGAGGAAACCGCACTTTTTTCCGCT
TTATGGCAGCCGAGCAAAGCCTGCGAAGATTATCAGGACGACGACGGACGTGTACTTTCCCGCGCACTTGCGGAAAATGT
CGTCAAACGCATTACCGACCAACCGGCAAAAGTCACCGATTACACGGATAAGAGGGAAAAAGAAACGGCACCGTTGCCAT
ATTCCCTTTCTGCATTGCAAATTGATGCCGCCAAGCGTTTCCGGATGTCGGCGCAGGAAGTGCTAGACACTTGCCAGCGT
TTGTATGAAACACACAAACTGATTACTTATCCGCGCTCCGATTGTCGTTATTTGCCGAAAGAACATTTTGCCGATCGTAT
GGCGGTGATGAATGCTATTTCTACTCATTTAACACCATTTCAACCCCTGCCCGAAATTATCGATCCTGAACAGAAAAACC
GTTGTTGGAACGATAAAAAAGTGGAAGCGCACCATGCCATTATTCCTACAGCCAAAAATCGTGCCGTTAGCTTAACCCAA
GCAGAACAAAACATATATTTTCTTATTGCTCGCCAATATCTCATGCAGTTTTGCCCCGACGCGGAATACCGTAAATGCAA
AATTACCTTGGATATCGTAGGCGGAACTTTCGTCGCGCAAGCGCGCAACTTACAAATTGCCGGTTGGAAACAACTTTGGG
GAAAAGAAGATAACGATGATGAACAGCCTGATGCCTTGTTGCCGGTGGTGAAAAAAGGACAGATTTTACATTGCGAGAAA
GGCGACATTGTCAGTAAAAAAACACAACCGCCGAAACCCTTTACCGATGCGACGTTGCTTTCTGCTATGACGGGTATTGC
CCGCTTTGTGCAAGACAAGGAATTGAAAAAAATTCTGCGAGAAACCGATGGATTAGGCACCGAGGCCACTCGGGCGGGGA
TTATTGAGTTGTTGTTTAAGCGGGGCTTTCTATATAAAAAAGGACGCAATATTCACAGCACCGAGGCAGGGCGTATTTTA
ATCAATGCCTTGCCGGATGTGGCAACTCAACCCGATATGACGGCACATTGGGAATCTCAACTGGACAGCATTAGTCGAAA
ACAGGCGAGTTATCAGCAATTTATGCAAAATCTTACCCAGCTTTTGCCTGAATTATTGCATTACATTAATTTTTCAGCTT
TACGTGAGTTGAGTCGGCATAATCAAGGCGTGAAAAAGACCGCATCGAGAACAAAGAAAAGTTAA

Protein sequence :
MRLFIAEKPSLGRAIADVLPKPHQRGDGFIKCGDNDYVTWCVGHLLEQAEPDAYDARFKQWRLEDLPIVPQKWLLIPKKE
THKQLKTVEKLVHQAEILVNAGDPDREGQLLVDEVFSYLNLPAEKRNAIQRCLISDLNPSAVEKAIKKLQPNRDFIPLAT
SALARARADWLYGINMTRAYTIRGRQAGYNGVLSVGRVQTPVLGLIVRRDLEIENFQPKDFFEVLAWVRDPKEETALFSA
LWQPSKACEDYQDDDGRVLSRALAENVVKRITDQPAKVTDYTDKREKETAPLPYSLSALQIDAAKRFRMSAQEVLDTCQR
LYETHKLITYPRSDCRYLPKEHFADRMAVMNAISTHLTPFQPLPEIIDPEQKNRCWNDKKVEAHHAIIPTAKNRAVSLTQ
AEQNIYFLIARQYLMQFCPDAEYRKCKITLDIVGGTFVAQARNLQIAGWKQLWGKEDNDDEQPDALLPVVKKGQILHCEK
GDIVSKKTQPPKPFTDATLLSAMTGIARFVQDKELKKILRETDGLGTEATRAGIIELLFKRGFLYKKGRNIHSTEAGRIL
INALPDVATQPDMTAHWESQLDSISRKQASYQQFMQNLTQLLPELLHYINFSALRELSRHNQGVKKTASRTKKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 4e-105 42
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 2e-101 42
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 3e-107 41
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 3e-107 41
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 2e-107 41