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Name : lysS (NT05HA_1183) Accession : YP_003007631.1 Strain : Aggregatibacter aphrophilus NJ8700 Genome accession: NC_012913 Putative virulence/resistance : Virulence Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : - Position : 1190151 - 1191659 bp Length : 1509 bp Strand : + Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA DNA sequence : ATGTCAGAACAAGAAGTAAAAGAGTTAGATCTCAACGGCGAAATGTTAGTTCGCCGTGAAAAACTCGCGGCCTTGCGTGC CAAAGGCAATGCCTTCCCGAACCGATTCCGCCGTGATGCGTTAGCTAAAGCATTACATGATCAATATGAAGCCGAAGACG GTGAAGCATTAAAAGAAAAACATATTGAAGTTGCTGTCGCCGGCCGTATCATGACCCGTCGCGCCATGGGTAAAGCCACC TTCATCACACTACAAGACATGAGTGGACGCATTCAGCTTTATGTGGCGCGCGATAACTTGCCTGAAGGCGTTTACAAAGA GGATGTCGGCGCGTGGGATTTAGGCGATATCGTGGGCGTAAAAGGCACATTATTTAAAACCAAAACCAACGAACTCACCG TCAAAGCCACCGAAGTGCAATTGCTTACAAAAGCGTTGCGTCCGTTGCCCAATAAGTTCCACGGATTAACCGACCAAGAA GTGCGTTATCGTCAACGTTATTTAGATTTAATTGCTAACGAGGACTCCCGCCGCACTTTTATGATTCGCTCCCAAGTGGT TGCCGGTATCCGTGAATATTTCATTTCCAAAGGCTTTATGGAAGTCGAAACCCCGATGTTACAAGTGATCCCGGGTGGCG CGGCGGCGCGTCCGTTCGTGACGCACCACAACGCATTAGACGTGGATATGTACTTGCGTATCGCCCCTGAGCTTTATTTA AAACGCTTAGTGGTCGGCGGCTTTGAACGCGTATTTGAACTTAACCGCAACTTCCGTAATGAAGGCGTATCCGTTCGTCA CAATCCGGAATTCACCATGCTTGAATACTACCAAGCCTATGCCGATTACCACGATTTAATGGATAACACCGAAGAACTGT TGCGTAAACTTGCCATCGATATTTTAGGCACAACCATTGTGAAATACGGCGAATACGAATTTGATTTCGGTAAGCCGTTC GAGCGTATCACGTTACACGACGCTACCATTAAATATGGTGCTGAAAAAGGCATCGTAAAAGAAGATTTATACGACTTAGA GCGCGCTAAAGCTGCGGCAAAACGTTTAGGTATTGAAGTACAAAAATCTTGGGGCTTGGGTAGCATTGTCAATGCGATTT TTGAAGAAGTGGCGGAACATCATTTAATTCAACCGACTTTCTTAATGGCTCACCCGGCGGAAATTTCACCGTTGGCACGT CGTAACGATGAAAACCCGGAAGTCACCGATCGCTTTGAACTCTTCATCGGCGGACGTGAAATCGGCAACGGTTTCTCCGA ATTGAACGATGCCGAAGATCAAAATGAACGTTTTGACGCCCAGGTGGCCGCCAAAGAAGCTGGTGATGACGAAGCGATGT TTAAAGACGAAGATTTCGTTGTAGCCCTTGAACACGGCTTGCCACCAACGGCCGGCGAAGGCTTGGGTATCGACCGCTTA GCCATGCTTTATGCCAATGCTCCATCCATCCGTGATGTGATTTTGTTCCCGGCGATGCGTCAGAAATAA Protein sequence : MSEQEVKELDLNGEMLVRREKLAALRAKGNAFPNRFRRDALAKALHDQYEAEDGEALKEKHIEVAVAGRIMTRRAMGKAT FITLQDMSGRIQLYVARDNLPEGVYKEDVGAWDLGDIVGVKGTLFKTKTNELTVKATEVQLLTKALRPLPNKFHGLTDQE VRYRQRYLDLIANEDSRRTFMIRSQVVAGIREYFISKGFMEVETPMLQVIPGGAAARPFVTHHNALDVDMYLRIAPELYL KRLVVGGFERVFELNRNFRNEGVSVRHNPEFTMLEYYQAYADYHDLMDNTEELLRKLAIDILGTTIVKYGEYEFDFGKPF ERITLHDATIKYGAEKGIVKEDLYDLERAKAAAKRLGIEVQKSWGLGSIVNAIFEEVAEHHLIQPTFLMAHPAEISPLAR RNDENPEVTDRFELFIGGREIGNGFSELNDAEDQNERFDAQVAAKEAGDDEAMFKDEDFVVALEHGLPPTAGEGLGIDRL AMLYANAPSIRDVILFPAMRQK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66193.1 | putative lysil-tRNA synthetase LysU | Not tested | PAI III 536 | Protein | 1e-152 | 63 |
| lysS | YP_005163386.1 | lysyl-tRNA synthetase | Not tested | Not named | Protein | 2e-89 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lysS | YP_003007631.1 | lysyl-tRNA synthetase | VFG1668 | Protein | 8e-153 | 63 |
