Gene Information

Name : tpx (Dd1591_1768)
Accession : YP_003004099.1
Strain : Dickeya zeae Ech1591
Genome accession: NC_012912
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2023711 - 2024214 bp
Length : 504 bp
Strand : -
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGTCAACAAATGTACATTTTCAGGGTAATCCGGTACCGGTAGCAGGATCGTTCCCGGCCGCAGGCAGCAAAGCGCCGGC
GTTTTCACTGGTTGCCAAAGATCTTGCTGATGTGGCGCTGAGCCACTACGCAGGCAAGCGTAAAGTCCTGAACATTTTCC
CAAGCATCGATACCGGTGTATGTGCCGCGTCCGTGCGTAAATTCAACCAGTTGGCTTCCAGCCTCGATAATACCGTCGTA
CTGTGCATTTCCGCCGACCTGCCGTTTGCCCAGTCTCGCTTCTGCGGTGCCGAAGGTTTGAACAATGTGGTCGTGCTGTC
TACTCTGCGCGGCGCGGAATTCAAAGAAAACTACGGTGTAGCGATTGCCGAAGGCGCCCTGAAAGGGCTGACTGCCCGTG
CCGTCGTGGTGCTGGATGAAAACGACGACGTACTGCACAGCGAGCTGGTGAACGAAATCACTAACGAGCCGGACTACGAT
GCGGCCATCGCCGTACTGAAGTAA

Protein sequence : 
MSTNVHFQGNPVPVAGSFPAAGSKAPAFSLVAKDLADVALSHYAGKRKVLNIFPSIDTGVCAASVRKFNQLASSLDNTVV
LCISADLPFAQSRFCGAEGLNNVVVLSTLRGAEFKENYGVAIAEGALKGLTARAVVVLDENDDVLHSELVNEITNEPDYD
AAIAVLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 5e-37 51
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 3e-37 51
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 4e-37 51
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 2e-37 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_003004099.1 thiol peroxidase VFG0087 Protein 7e-38 51