Gene Information

Name : irr (SDEG_0927)
Accession : YP_002996640.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Resistance
Product : two-component response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 911795 - 912448 bp
Length : 654 bp
Strand : +
Note : similar to two-component response regulator [Streptococcus pyogenes MGAS5005]

DNA sequence : 
ATGTTTAAAATATTAGTAGTTGAAGATGATGATACTATCAGTCAAGTGATTTGTGAGTTTTTAAAAGCGAATAACTATGA
TCCAGATTGTGTGTTTGATGGCCAAGCTGCCTTAGACAAGTGGCAGACAACGTCTTATGATCTGATTATTTTAGACATCA
TGCTCCCTTCCTTAAGTGGCTTAGAAGTGCTAAAAACAATTCGAAAGACATCAGATATCCCTATTATTATGCTAACGGCA
TTAGATGACGAGTACACACAGCTTGTAAGCTTCAACCATTTGATTAGTGATTATGTGACCAAACCATTTTCACCACTCAT
TTTAATCAAACGTATCGAAAATGTATTACGCGTCTCTACTCCAGATGAAAAGCACCAAATCGGAGACTTACTTGTTGATG
AGATCGAACATAGCGTCTATTGGCAAGGAACATTGGTCAAACTAACTAAAAAAGAGTATGATATTATTGATTATTTAGCA
AAACGTCACCAAAAGGTTGTCACCAGAGACCAATTGATGGATGACATATGGGGCTATTCTGAACTGGACACGCGTGTACT
TGACAACCACATCAAGAACCTTCGTAAAAAAATGACGGGCATTCCCCTCAAGACAATTACAGGCATGGGCTATTTATTGG
GAGAGCGTGAGTGA

Protein sequence : 
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDIPIIMLTA
LDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKHQIGDLLVDEIEHSVYWQGTLVKLTKKEYDIIDYLA
KRHQKVVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
vanRB YP_008394254.1 DNA-binding response regulator VanRB Not tested Not named Protein 2e-34 41
vanRB NP_815956.1 DNA-binding response regulator VanRB Not tested Not named Protein 5e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irr YP_002996640.1 two-component response regulator HE999704.1.gene1202. Protein 1e-35 41
irr YP_002996640.1 two-component response regulator AF310956.2.orf0.gene Protein 8e-35 41
irr YP_002996640.1 two-component response regulator AE016830.1.gene2255. Protein 2e-34 41
irr YP_002996640.1 two-component response regulator U35369.1.gene1.p01 Protein 2e-34 41