Gene Information

Name : vicR (SDEG_0569)
Accession : YP_002996285.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Virulence
Product : two-component response regulator
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG0745
EC number : -
Position : 538077 - 538787 bp
Length : 711 bp
Strand : +
Note : similar to two-component response regulator [Streptococcus pyogenes MGAS5005]

DNA sequence :
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAATTTGACAAAAGAAGGTTATGA
CATTGTTACAGCTTTTGATGGACGCGAAGCGGTAACAATTTTTGAAGAAGAAAAGCCAGATTTAATTATTCTTGATTTGA
TGCTCCCTGAGTTGGACGGTCTTGAAGTAGCCAAGGAAATTCGTAAAACCAGTCATGTCCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGTCTTGAAATTGGGGCAGATGATTATGTTACCAAACCTTTTTCAAATCGTGA
ACTATTAGCTCGTGTCAAGGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACCATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGACGTGACGGTTCGTCGTCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTACTACATGAAATCTTATGACTAG

Protein sequence :
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTIFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 7e-36 43
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 9e-36 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vicR YP_002996285.1 two-component response regulator NC_012469.1.7685629. Protein 1e-81 80
vicR YP_002996285.1 two-component response regulator HE999704.1.gene2815. Protein 2e-50 54
vicR YP_002996285.1 two-component response regulator NC_002952.2859905.p0 Protein 7e-50 52
vicR YP_002996285.1 two-component response regulator NC_002951.3237708.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_002758.1121668.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_003923.1003749.p0 Protein 7e-50 52
vicR YP_002996285.1 two-component response regulator NC_009641.5332272.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_013450.8614421.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_007793.3914279.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_007622.3794472.p0 Protein 7e-50 52
vicR YP_002996285.1 two-component response regulator NC_002745.1124361.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_009782.5559369.p0 Protein 9e-50 52
vicR YP_002996285.1 two-component response regulator NC_012469.1.7686381. Protein 1e-42 48
vicR YP_002996285.1 two-component response regulator AE016830.1.gene1681. Protein 1e-43 46
vicR YP_002996285.1 two-component response regulator AF155139.2.orf0.gene Protein 2e-38 44
vicR YP_002996285.1 two-component response regulator FJ349556.1.orf0.gene Protein 4e-38 44
vicR YP_002996285.1 two-component response regulator CP001918.1.gene5135. Protein 2e-25 44
vicR YP_002996285.1 two-component response regulator AM180355.1.gene1830. Protein 2e-37 43
vicR YP_002996285.1 two-component response regulator DQ212986.1.gene4.p01 Protein 8e-38 43
vicR YP_002996285.1 two-component response regulator BAC0533 Protein 2e-30 43
vicR YP_002996285.1 two-component response regulator CP000034.1.gene3834. Protein 6e-30 43
vicR YP_002996285.1 two-component response regulator CP001138.1.gene4273. Protein 5e-30 43
vicR YP_002996285.1 two-component response regulator CP000647.1.gene4257. Protein 2e-30 43
vicR YP_002996285.1 two-component response regulator CP004022.1.gene3215. Protein 1e-32 43
vicR YP_002996285.1 two-component response regulator NC_002695.1.915041.p Protein 6e-30 43
vicR YP_002996285.1 two-component response regulator AF162694.1.orf4.gene Protein 7e-35 42
vicR YP_002996285.1 two-component response regulator AE000516.2.gene3505. Protein 2e-33 41
vicR YP_002996285.1 two-component response regulator NC_002952.2859858.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_007622.3794948.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_003923.1003417.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_013450.8614146.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_002951.3238224.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_007793.3914065.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_002758.1121390.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator NC_010079.5776364.p0 Protein 2e-34 41
vicR YP_002996285.1 two-component response regulator AE015929.1.gene1106. Protein 3e-30 41
vicR YP_002996285.1 two-component response regulator BAC0596 Protein 1e-27 41
vicR YP_002996285.1 two-component response regulator BAC0039 Protein 2e-28 41
vicR YP_002996285.1 two-component response regulator CP001138.1.gene2239. Protein 1e-27 41
vicR YP_002996285.1 two-component response regulator CP000034.1.gene2186. Protein 2e-28 41
vicR YP_002996285.1 two-component response regulator NC_002695.1.916589.p Protein 2e-28 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
vicR YP_002996285.1 two-component response regulator VFG1563 Protein 4e-36 43
vicR YP_002996285.1 two-component response regulator VFG1389 Protein 1e-31 43
vicR YP_002996285.1 two-component response regulator VFG1702 Protein 4e-36 42