Gene Information

Name : nrdE1 (SDEG_0476)
Accession : YP_002996192.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 447746 - 449932 bp
Length : 2187 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCACACCCCAATGAGTCATACCTCTCATTCAATGCCTTAACCCGCTTTAAAAAAACAGACGGAAGCTACCATTTTGA
TAGCGATGCCATTGCTGTTGAGCGCTACCTAGACGAACAGATTTCTCCCAATCTAGTGATGTTTCCATCTTTAGAAGAGA
AACTAGCTTATCTCATTAAGGAAGGTTATTATGAGCAAGCTATCTTTGATCTCTATCCTGATGACGTTATCAAGGAAGCC
TTTCAATATGCCTACCAACAAGACTATCGTTTTTTAAACTTGATGGGAGCCATGAAATTTTACCAATCTTATGCCTTAAA
AACTTTAGATGGCAAGTATTATCTAGAAACAGTTGAAGACCGTGTGGTCATGAATGCTCTCTTTTTAGCAAATGGGGATC
AAACGTTACTATTTAACTTGATAAAGGACATGTTACACAGGCGATTTCAACCAGCAACACCAACTTTTTTAAATGCTGGT
AAAAAACGACGGGGAGAATATATCTCTTGCTATCTGCTGCGTATTGAAGATAATATGGAATCCATTTCACGGGCAATAGG
GACCAGTCTTCAACTGTCTAAGAGAGGAGGAGGGGTGGCCTTATGCTTGACCAATCTTCGAGAAATTGGGGCACCAATAA
AAGAAATTGAAAATCAGGCAACGGGTATCGTTCCTGTCATGAAATTATTAGAAGATTCCTTTTCCTACGCCAACCAATTA
GGACAGCGTCAAGGTGCAGGTGCCGTTTACCTACATGCCCATCACCCAGAAGTTCTTACCTTTTTGGATACTAAAAGAGA
AAATGCCGATGAGAAAATTCGTATCAAGTCACTAGCCTTAGGGTTAGTTATTCCAGATATTACCTTCCAATTGGCAAAAG
AAAACAAAGAAATGGCCCTCTTTTCGCCATACGATATTAAACGCGTTTATGGTAAGGACATGTCAGACATTTCCATCACA
GAGGAATATAACAAACTGCTAGCCAATCCAGCCATTAAAAAGACCTATATCAGCGCTAGAAAACTTTTCCAATTGATTGC
AGAATTGCATTTTGAGTCTGGATACCCTTACCTCTTGTTTGATGATACAGTCAATCAGCGTAATCCTCATGCTCAAAAAG
GACGGATTGTCATGTCAAACTTATGTTCTGAAATTGCTCAAGTGAGTACAGAAAGTACCTACAACGATGATCTGAGCTTC
AAAGACATTGGAGAAGACATTTGTTGTAATCTGGGGTCAATCAATATCGCTGAAGCCATGACTGATGCCAAACATTTTAG
CCAGCTAATCACGACAAGTATCAGAGCTTTAGATCAAGTATCAAGAGCTTCTGATTTGTCTTGCGCCCCTTCTATTGAAA
AAGGCAATGCAGCTAATCACGCTGTTGGTCTAGGAGCAATGAATTTACATGGCTTTTTGGCAACTAATCATCTTTACTAT
GATTCAGAAGAAGCTGTTGACTTTACAGATTTGTTTTTCCATACTATGGCCTATCACGCTTTTAAAGCCTCTTGTCAATT
GGCTAAAGAAAAGGGGGCTTTTGCAGATTTTGAACGGTCGACCTATGCCGATGGTTCTTACTTTAAGCAGTATGTGATAG
AAGATGCCAAACCTAAAACAAAACGGATTGCTGCCTTGTTAAAAAGTTATGGCTTCCAATTACCAACTGTTGCTGATTGG
AAGGCATTGGTAAGGGATATTCAAACCTATGGCTTAGCCAATGCACATTTATTGGCCGTCGCTCCGACAGGGTCAATCAG
TTACTTATCTTCTTGCACTCCAAGTTTACAGCCAGTTGTTGCTCCTGTTGAAGTGCGTAAAGAGGGGAATTTAGGTAGAA
TTTATGTCCCGGCTTATCAGATTAATCAAGAAAATTATGCTTATTATGAACGTGGGGCCTATGAAATGGGTCCAGAACCC
ATTATTAAGATTGTAGCAGCAGCTCAAAAACATGTGGATCAAGCTATTTCATTGACTTTATTTATGACTGATCAGGCTAC
CACACGTGATCTTAACCGTTCTTATATTCAAGCTTTTAAACTAAAATGTGCTTCGATTTACTATGTTCGAGTGAGACAAG
AAGTTTTAGCAGGCAGTGAACAATACGACGAGGATAGCCAGTTGGATAGTGTAGATAAAAATGGACTTACAGACACAATC
AATGAGTGTCAAAGTTGCATGATTTAG

Protein sequence :
MSHPNESYLSFNALTRFKKTDGSYHFDSDAIAVERYLDEQISPNLVMFPSLEEKLAYLIKEGYYEQAIFDLYPDDVIKEA
FQYAYQQDYRFLNLMGAMKFYQSYALKTLDGKYYLETVEDRVVMNALFLANGDQTLLFNLIKDMLHRRFQPATPTFLNAG
KKRRGEYISCYLLRIEDNMESISRAIGTSLQLSKRGGGVALCLTNLREIGAPIKEIENQATGIVPVMKLLEDSFSYANQL
GQRQGAGAVYLHAHHPEVLTFLDTKRENADEKIRIKSLALGLVIPDITFQLAKENKEMALFSPYDIKRVYGKDMSDISIT
EEYNKLLANPAIKKTYISARKLFQLIAELHFESGYPYLLFDDTVNQRNPHAQKGRIVMSNLCSEIAQVSTESTYNDDLSF
KDIGEDICCNLGSINIAEAMTDAKHFSQLITTSIRALDQVSRASDLSCAPSIEKGNAANHAVGLGAMNLHGFLATNHLYY
DSEEAVDFTDLFFHTMAYHAFKASCQLAKEKGAFADFERSTYADGSYFKQYVIEDAKPKTKRIAALLKSYGFQLPTVADW
KALVRDIQTYGLANAHLLAVAPTGSISYLSSCTPSLQPVVAPVEVRKEGNLGRIYVPAYQINQENYAYYERGAYEMGPEP
IIKIVAAAQKHVDQAISLTLFMTDQATTRDLNRSYIQAFKLKCASIYYVRVRQEVLAGSEQYDEDSQLDSVDKNGLTDTI
NECQSCMI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 4e-180 55