Gene Information

Name : leuS (SDEG_2014)
Accession : YP_002997710.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1949882 - 1952383 bp
Length : 2502 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGACATTTTACGATCACACCGCTATTGAACCCAAATGGCAAGCCTTCTGGGCTGACAATCACACGTTTAAGACAGGAAC
AGACGCTTCGAAACCTAAGTTTTATGCGCTTGATATGTTTCCTTACCCTTCAGGAGCCGGTCTTCACGTCGGACACCCGG
AAGGATACACAGCAACAGATATTTTAAGTCGCTTTAAACGTGCTCAAGGTTACAATGTCTTGCACCCAATGGGGTGGGAT
GCCTTTGGTTTGCCTGCTGAGCAATATGCTATGGATACCGGTAATGATCCAGCAGAGTTTACAGCGGAAAATATTGCTAA
CTTCAAACGCCAAATCAATGCCCTTGGTTTTTCTTATGATTGGGACCGTGAGGTTAATACCACTGACCCAGACTACTACA
AGTGGACGCAATGGATTTTTACCAAATTGTATGAAAAAGGCTTGGCCTATGAGGCAGAGGTTCCTGTGAACTGGGTAGAA
GAGTTGGGAACAGCTATTGCCAATGAGGAAGTTCTGCCTGATGGAACTTCTGAGCGTGGTGGCTACCCTGTTGTCCGCAA
ACCAATGCGCCAATGGATGCTTAAAATCACGGCCTATGCTGAACGTCTTTTAGAAGATTTAGAAGAGGTTGACTGGCCAG
AGTCTATCAAGGACATGCAGCGTAACTGGATTGGTAAGTCAACCGGTGCCAATGTGACCTTCAAGGTTAAAGGCAGTGAC
AAAGACTTTACCGTCTTTACCACGCGCCCTGACACCTTGTTTGGAGCGACTTATGCTGTTTTGGCGCCAGAACATGCCCT
TGTTGACGAGATTACTAGCCCCGAACAAGCTGAAGCCGTGGCAGACTATAAACGCCAAGCGAGCTTGAAATCTGACTTGG
CCCGCACTGACCTCGCTAAGGAAAAAACAGGTGTTTGGACGGGTAGCTACGCTATTAACCCGGTCAACGGCAAAGAAGTG
CCAATCTGGATTGCTGACTACGTGCTAGCAAGTTATGGTACAGGTGCTATTATGGCTGTACCTGCCCACGACGAACGCGA
TTGGGAATTTGCTAAACAATTTGACCTTGAGATTATTCCAGTGCTTGAGGGTGGTAATGTGGCAGAAGCTGCTTACACCG
AGGATGGACGTCACATTAATTCCGACTTCTTAGACGGTCTAGACAAGGCTGATGCAATCGCTAAGATGGTAGCTTGGCTT
GAAGACAAGGAAGTTGGAAATGAAAAAGTGACTTACCGCTTGCGTGACTGGCTCTTTAGCCGCCAACGTTATTGGGGGGA
GCCGATTCCAATTATTCACTGGGAGGATGGCACCTCAACAGCTGTTCCTGAAAATGAGTTGCCGCTTGTCTTGCCAGTAA
CTTCAGATATTCGCCCTTCAGGAACAGGTGAATCACCACTAGCTAACTTGACTGATTGGTTAGAAGTGACCCGCGAAGAT
GGTGTTAAAGGTCGTCGTGAGACCAATACTATGCCACAGTGGGCTGGTTCAAGCTGGTATTATTTGCGTTACATTGACCC
TAAAAATGATCAAGCTTTGGCGGACCCAGAATTATTGAAACAATGGCTGCCTGTTGATATTTACGTGGGTGGTGCTGAAC
ATGCAGTGCTTCATCTCCTGTATGCCCGTTTCTGGCATAAAGTCCTTTACGATTTAGGCGTTGTGCCAACCAAAGAACCA
TTCCAAAAACTCTTTAACCAAGGGATGATTTTGGGAACGAGTTACCGTGACCATCGTGGAGCGCTTGTAGCGACTGACAA
GGTGGAAAAACGTGATGGCAGCTTCTTCCATATCGAAACAGGTGAGGAGCTTGAACAAGCACCAGCAAAAATGTCTAAAT
CACTCAAAAACGTTGTCAATCCTGATGACGTGGTGGAACAATACGGTGCGGATACCTTGCGTGTGTATGAAATGTTCATG
GGGCCATTAGATGCCTCAATCGCTTGGAGCGAAGAAGGCTTAGAAGGTTCTCGTAAGTTCCTTGACCGCGTCTACCGTTT
GGTAACGACTAGGGAGATTGTGGCGGAAAATAGCGGCGCCTTGGATAAAGTTTACAACGAAACTGTCAAAGCTGTTACTG
AACAAATTGAGACCATGAAGTTCAATACTGCTATTGCTCAATTGATGATTTTTGTCAATGCAGCTAACAAAGAAGACCAG
TTGTTTGTGGACTATGCCAAAGGCTTTGTGCAATTGATTGCTCCATTTGCGCCACACTTGGGTGAAGAACTCTGGCAAAT
GATTACTCAATCAGATGAGTCCATTGCTCATGTGGCTTGGCCAACTTGGGATGAGTCCAAATTGGTTGAAAACGATGTGG
AAATCGTTGTCCAAATCAAAGGAAAAGTCAAAGCGAAATTAGTGGTTGCTAAGGATCTTTCTAGGGAAGACTTAGAAGCT
GCAGCCCTTGCTAATGAGAAAGTACAAGCTGAGATTGCAGGCAAAGACATTGTCAAAGTGATTGCAGTCCCTAACAAGCT
TGTTAATATCGTGGTAAAGTAA

Protein sequence :
MTFYDHTAIEPKWQAFWADNHTFKTGTDASKPKFYALDMFPYPSGAGLHVGHPEGYTATDILSRFKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPAEFTAENIANFKRQINALGFSYDWDREVNTTDPDYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLEDLEEVDWPESIKDMQRNWIGKSTGANVTFKVKGSD
KDFTVFTTRPDTLFGATYAVLAPEHALVDEITSPEQAEAVADYKRQASLKSDLARTDLAKEKTGVWTGSYAINPVNGKEV
PIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIPVLEGGNVAEAAYTEDGRHINSDFLDGLDKADAIAKMVAWL
EDKEVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPENELPLVLPVTSDIRPSGTGESPLANLTDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPKNDQALADPELLKQWLPVDIYVGGAEHAVLHLLYARFWHKVLYDLGVVPTKEP
FQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFHIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLVTTREIVAENSGALDKVYNETVKAVTEQIETMKFNTAIAQLMIFVNAANKEDQ
LFVDYAKGFVQLIAPFAPHLGEELWQMITQSDESIAHVAWPTWDESKLVENDVEIVVQIKGKVKAKLVVAKDLSREDLEA
AALANEKVQAEIAGKDIVKVIAVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 94