Gene Information

Name : SDEG_2002 (SDEG_2002)
Accession : YP_002997698.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.6
Position : 1934223 - 1936865 bp
Length : 2643 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
ATGGAAAACAAGAATAAATTACTGTTAATTGATGGGTCATCTGTTGCCTTTCGTGCCTTTTTTGCCCTCTACAATCAAAT
CGACCGTTTTAAAAATCATAGCGGTCTTCATACCAATGCCATTTATGGCTTTCATTTGATGTTAGAGCACATGATGAAGC
GAGTCCAGCCCACACACGTGCTGGTGGCTTTTGATGCGGGCAAAACCACCTTCCGGACAGAAATGTATGCAGACTACAAG
GCTGGTCGCGCCAAGACACCAGAGGAGTTTCGTGAGCAATTTCCTTATATTCGTGAGATGTTGACAGCCCTTGGTATTGC
TTATTATGAGTTGGAACATTACGAAGCCGATGATATTATTGGGACGCTTGATAAAATGGCGGAGCGCACAGAAGTGCCTT
TTGATGTGACCATTGTCAGTGGTGATAAAGATTTGATCCAGTTAACTGACGAAAATACCGTGATTGAAATTTCTAAAAAA
GGGGTTGCCGAATTTGAAGAATTCACACCGGCTTACCTCATGGAAAAAATGGGCTTGACGCCAAACCAGTTTATTGACCT
CAAAGCCTTGATGGGAGATAAATCGGATAATATTCCAGGAGTGACCAAAATCGGTGAAAAAACTGGGCTCAAGCTCCTTC
ATGAATTTGGTAGTTTAGAAGGTATCTACGAGCACGTTGAAGGTTTCAAAGCTTCCAAAATGAAAGAAAACTTGCTCAAT
GATCGTGACCAAGCTTTTCTGTCTAAAACGCTCGCCACTATCAATACAGCATCTCCTATCACAATTGGCTTAGATGATAT
TGTCTACAATGGTCCTGATGTTGCTAGTCTGTCTAAGTTTTACGATGAAATGGATTTTGTCCAACTGAAAAAAGGTTTGG
CGAGTCAGATGCCTCAAGAAGCTATCGCCGCTGTTTCTTACCAAGAAGTTACTTCCCTCTCTGATGATCTTTTTAGTGAT
GAGGACATCTTCTACTTTGAAGTGCTTCGGGATAATTATCATCGTGAGGACATCATTGGCTTTGCATGGGGACACGGGGA
GCAGATTTATGCGTCAACTGACCTCAGCTTGTTATCAACTGACCTTTTCAAAAAGGTTTTTGAAAAACCAATTGCCACCT
ATGACTTTAAGCGTAGCAAGGTCTTGTTGAGCCACTTAGGAATTGAGTTGGTAGCACCTAGCTATGATGCTAGATTGGCT
AACTACCTTCTTTCAAATGTGGAAGACAATGAACTCACTACTATTGCAAGGCTTTTCACCGACATTTCCCTAGAAGCAGA
TGACAGCATTTATGGCAAGGGTGTCAAAAGAGCTGTTCCTGAAAAAGAGGTTCTGCTTGGGCATTTAGCCCGCAAAGTCA
AGGTTCTTTTGGATAGTAGAGCGCCTATGGTGGAGAAATTAGCTGACCATGATCAAATTGATCTTTACCATGAGATTGAG
TTACCGTTAGCGAACGTTCTTGCTAAAATGGAAATTGAAGGGATCAAGGTTAATAGGGCGACTTTGCAAGATATGGCAGA
GCAAAACAAGGTCATTATTGAAGCGCTCACCCAAGAGATTTATGATATGGCTGGCCAAGAATTTAATATCAATTCGCCTA
AACAGCTGGGCAGTATCTTGTTTGAGAAGATGCAGTTACCTCTTGAGATGACTAAGAAGACCAAAACAGGTTATTCTACA
GCTGTTGATGTTTTGGAACGTTTGGCACCGATTGCTCCAATTGTGGCTAAAATTTTGGATTATCGCCAAATTACTAAATT
GCAATCCACCTATGTGATTGGTTTACAGGATTATATTCTGGCTGATGGCAAGATTCATACCCGCTATGTGCAGGATCTCA
CCCAGACAGGTCGTTTGTCTAGTGTTGACCCTAACCTCCAAAACATTCCCATTCGTTTGGAACAGGGGCGTTTGATTCGT
AAGGCCTTTACCCCATCTCATGAAGATGCCGTCTTGTTGAGTTCAGATTACTCACAGATTGAATTGCGGGTACTGGCACA
TATTTCAGGGGATGAGCATTTGATTGCTGCCTTTAATGAAGGGGCAGACATTCATACCTCAACGGCTATGCGTGTGTTTG
GGATTGACAAGGCAGCAGATGTTACTGCCAATGACCGCCGTAATGCCAAGGCTGTTAATTTTGGTATCGTCTATGGGATT
TCGGATTTTGGTTTGTCAAATAACCTTGGTATCACCCGGAAACAGGCCAAGTCTTACATTGATACCTATTTTGAACGCTA
TCCTGGCATCAAAGCCTATATGGAAAATGTCGTTCGTGAGGCTAAAGACAAGGGCTATGTGGAAACCCTCTTTAAGCGTC
GTCGTGAATTACCGGATATCAACTCTCGTAATTTCAACGTTCGCTCTTTTGCGGAGCGTACAGCCATCAACTCGCCCATT
CAAGGGAGCGCAGCTGATATTCTCAAAATCGCTATGATTAACCTGGACAACGCCTTGCAAGCAGGTGGTTTTAAAGCTAA
AATGCTCCTTCAAGTGCACGATGAAATCGTTTTGGAAGTGCCAAATGATGAGTTGACTGCTATAAAAAAACTTGTCAAAG
ACACCATGGAAGCTGCTGTTGATTTAGCTGTTCCTTTACGCGCAGATGAAAATGCAGGACAGAGCTGGTACGAAGCCAAG
TAA

Protein sequence :
MENKNKLLLIDGSSVAFRAFFALYNQIDRFKNHSGLHTNAIYGFHLMLEHMMKRVQPTHVLVAFDAGKTTFRTEMYADYK
AGRAKTPEEFREQFPYIREMLTALGIAYYELEHYEADDIIGTLDKMAERTEVPFDVTIVSGDKDLIQLTDENTVIEISKK
GVAEFEEFTPAYLMEKMGLTPNQFIDLKALMGDKSDNIPGVTKIGEKTGLKLLHEFGSLEGIYEHVEGFKASKMKENLLN
DRDQAFLSKTLATINTASPITIGLDDIVYNGPDVASLSKFYDEMDFVQLKKGLASQMPQEAIAAVSYQEVTSLSDDLFSD
EDIFYFEVLRDNYHREDIIGFAWGHGEQIYASTDLSLLSTDLFKKVFEKPIATYDFKRSKVLLSHLGIELVAPSYDARLA
NYLLSNVEDNELTTIARLFTDISLEADDSIYGKGVKRAVPEKEVLLGHLARKVKVLLDSRAPMVEKLADHDQIDLYHEIE
LPLANVLAKMEIEGIKVNRATLQDMAEQNKVIIEALTQEIYDMAGQEFNINSPKQLGSILFEKMQLPLEMTKKTKTGYST
AVDVLERLAPIAPIVAKILDYRQITKLQSTYVIGLQDYILADGKIHTRYVQDLTQTGRLSSVDPNLQNIPIRLEQGRLIR
KAFTPSHEDAVLLSSDYSQIELRVLAHISGDEHLIAAFNEGADIHTSTAMRVFGIDKAADVTANDRRNAKAVNFGIVYGI
SDFGLSNNLGITRKQAKSYIDTYFERYPGIKAYMENVVREAKDKGYVETLFKRRRELPDINSRNFNVRSFAERTAINSPI
QGSAADILKIAMINLDNALQAGGFKAKMLLQVHDEIVLEVPNDELTAIKKLVKDTMEAAVDLAVPLRADENAGQSWYEAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 95