Gene Information

Name : secA (SDEG_1868)
Accession : YP_002997564.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1794953 - 1797481 bp
Length : 2529 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCCAATATTCTACGCAAAGTCATCGAAAATGACAAAGGCGAACTAAGAAAATTAGAAAAAATTGCAAGAAAAGTAGA
ATCTTACGCAGACCACATGGCGTCATTGTCAGATAGAGATCTACAAGCAAAAACACCAGAATTTAAAGAGCGATATCAAA
AAGGGGAAACCCTTGAACAATTACTTCCCGAAGCATTTGCGGTTGTCCGTGAAGCTTCAAAACGCGTGCTTGGTTTGTAT
CCATACCGTGTTCAAATCATGGGGGGAGTTGTCCTTCACAACGGAGATGTGCCTGAAATGCGTACCGGTGAAGGGAAAAC
CTTGACTGCGACCATGCCTGTTTACCTTAACGCCCTTGCAGGCGAAGGCGTGCACGTTATCACTGTCAACGAGTATTTGT
CAACCCGTGATGCGACTGAGATGGGTGAAGTGTATAGTTGGCTAGGCCTTTCTGTGGGGATTAACTTAGCAGCTAAATCT
CCGGCAGAAAAACGTGAAGCTTACAACTGTGACATTACCTACTCAACTAACTCTGAAGTCGGATTTGACTATTTGCGTGA
TAACATGGTTGTCCGTCAAGAGGATATGGTGCAGCGCCCGCTCAATTTTGCCTTAGTCGATGAAGTCGATTCCGTTTTGA
TTGACGAAGCGAGAACACCTTTGATTGTTTCAGGAGCTGTTAGCTCGGAAACCAATCAATTGTATATCCGTGCAGATATG
TTTGTGAAAACCTTGACAGTAGATGATTACATCATTGACGTCCCAACCAAAACAATTGGTTTGAGTGATTCAGGGATTGA
CAAGGCGGAAAGTTACTTTAATTTAAACAATCTGTATGATATTGAAAATGTTGCCTTAACTCACTTTATTGATAATGCCC
TTCGTGCCAACTATATCATGTTGTTAGACATCGATTATGTGGTCAGCGAAGATGGTGAAATTCTCATTGTCGACCAATTT
ACTGGTCGTACGATGGAAGGTCGTCGTTTCTCAGATGGTTTGCACCAAGCTATTGAAGCCAAAGAAGGCGTTCGTATCCA
AGAAGAATCAAAAACCAGTGCCTCAATTACCTACCAGAACATGTTCCGTATGTACAAAAAATTGGCAGGGATGACAGGTA
CCGCTAAAACTGAAGAAGAGGAATTCCGCGAAGTTTATAACATGCGCATCATTCCAATTCCAACTAACCGCCCGATTGCG
CGTATTGACCACACGGACTTACTATACCCAACTCTAGAATCTAAGTTCAGAGCTGTGGTAGCACATGTCAAAGCGCGTCA
TGATAAAGGACAACCAATCCTTGTTGGTACCGTTGCTGTTGAGACAAGTGACTTAATTTCTCGCAAATTGGTGGAAGCTG
GTATTCCTCACGAAGTCTTAAATGCTAAAAATCACTTCAAAGAAGCACAAATCATTATGAATGCTGGCCAGCGTGGAGCG
GTGACCATTGCCACCAATATGGCAGGTCGTGGTACCGATATTAAACTGGGTGAAGGCGTTCGTGAACTTGGTGGGCTTTG
CGTGATTGGTACTGAACGTCACGAAAGCCGTCGTATTGATAACCAGCTTCGCGGCCGTTCAGGACGTCAAGGTGATCCAG
GTGAGTCACAATTCTACCTATCACTAGAAGATGATTTGATGAGACGTTTTGGTTCAGACCGTATCAAGGCCTTTTTGGAC
CGTATGAAATTAGACGAAGAAGATACAGTCATCAAGTCAGGTATGTTGGCACGCCAAGTCGAATCTGCTCAAAAACGTGT
TGAAGGGAACAACTACGATACCCGTAAACAAGTTTTGCAGTACGATGATGTGATGCGTGAGCAACGCGAGATTATTTACG
CTAACCGTCGTGATGTTATCACTGCCAACCGCGACCTTGGTCCAGAAATCAAAGCTATGATTAAGCGAACCATTGACCGT
GCGGTTGACGCTCATTCACGTAGCAATCGTAAGGATGCTGTGGATGCCATTGTGACCTTTGCACGCACGTCACTTGTTCC
AGAAGAGTCTATCAGTGCTAAAGAGTTACGTGGGTTGAAAGATGATCAAATCAAAGAAACCCTCTATCAAAGAGCTCTTG
CCATCTATGATCAACAAGTCTCAAAACTTCGCGATCAAGAAGCTATTATCGAATTCCAAAAAGTATTGATTTTGATGATT
GTGGACAATAAATGGACAGAACACATTGATGCTTTGGACCAGCTCCGCAATGCTGTTGGTCTGCGTGGTTATGCTCAAAA
TAACCCTGTGGTAGAGTATCAAGCAGAAGGCTTCAAAATGTTCCAGGACATGATTGGTGCCATTGAATTTGATGTGACCC
GTACCATGATGAAAGCGCAAATTCACGAACAAGAACGTGAACGTGCGAGTCAACATGCCACAACAGCAGCACCTCAAAAC
ATTCAATCACAGGCTTTTGTCGACGATAGAGAGGGAGATATTGATTTCTCAAAAGTTGAGCGTAATGCTGCCTGCCCATG
TGGTTCAGGTAAAAAATTCAAAAATTGTCATGGCCGCAGAGCTTTCTAA

Protein sequence :
MANILRKVIENDKGELRKLEKIARKVESYADHMASLSDRDLQAKTPEFKERYQKGETLEQLLPEAFAVVREASKRVLGLY
PYRVQIMGGVVLHNGDVPEMRTGEGKTLTATMPVYLNALAGEGVHVITVNEYLSTRDATEMGEVYSWLGLSVGINLAAKS
PAEKREAYNCDITYSTNSEVGFDYLRDNMVVRQEDMVQRPLNFALVDEVDSVLIDEARTPLIVSGAVSSETNQLYIRADM
FVKTLTVDDYIIDVPTKTIGLSDSGIDKAESYFNLNNLYDIENVALTHFIDNALRANYIMLLDIDYVVSEDGEILIVDQF
TGRTMEGRRFSDGLHQAIEAKEGVRIQEESKTSASITYQNMFRMYKKLAGMTGTAKTEEEEFREVYNMRIIPIPTNRPIA
RIDHTDLLYPTLESKFRAVVAHVKARHDKGQPILVGTVAVETSDLISRKLVEAGIPHEVLNAKNHFKEAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMRRFGSDRIKAFLD
RMKLDEEDTVIKSGMLARQVESAQKRVEGNNYDTRKQVLQYDDVMREQREIIYANRRDVITANRDLGPEIKAMIKRTIDR
AVDAHSRSNRKDAVDAIVTFARTSLVPEESISAKELRGLKDDQIKETLYQRALAIYDQQVSKLRDQEAIIEFQKVLILMI
VDNKWTEHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFKMFQDMIGAIEFDVTRTMMKAQIHEQERERASQHATTAAPQN
IQSQAFVDDREGDIDFSKVERNAACPCGSGKKFKNCHGRRAF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 2e-144 42