Gene Information

Name : serS (SDEG_1811)
Accession : YP_002997507.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1734256 - 1735533 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTAGATCTTAAACGTATTCGAACCGATTTTGACGCTGTCGCTGCCAAATTAAAAATCCGTGGGGTTTCAGAAGATAC
TCTAACACACCTCAAGAATCTTGATGAAAAACGTCGTGCTCTTCTCGTTCAATCAGAAGAATTAAAAGCAGAGCGTAATA
TTGCTTCTGCAGCCATCGCCCAAGCAAAACGCCAAAAAGAAGACGCTAGCCAACAGATTGCTGACATGCAAAACGTTTCT
GCCGACATCAAAACCATTGATAGCCAGCTCGCTGATATCGACCAGCAAGTGACTGACATCATCACTGTTTTACCTAATAC
TCCTCACGATTCTGTTCCTGTTGGTGCTGATGAAGAGGACAATGTCGAAATTCGCCGTTGGGGCACTCCTCGTGACTTTG
ACTTTGAGGTTAAGGCTCATTGGGATTTAGGTGAAGATCTCGATATTCTAGACTGGGAACGTGGAGCAAAGGTTACAGGT
GCTCGTTTCTTATTCTATAAAAATCTTGGCGCTCGTTTGGAACGTGCCCTATATAATTTTATGTTGGATGAACATATCAA
AGAGGGTTATCAGGAAATCATCACGCCATACATGGTCAACCATGATTCTATGTTTGGTACAGGTCAATATCCAAAATTCA
AGGAAGATACCTTTGAGTTATCAGACACAAACTTTGTTCTGATCCCAACGGCAGAAGTTCCATTGACCAATTATTACCGT
GGGGAAATTCTAGATGGCAAAGAGCTCCCAATTTACTTTACAGCGATGAGCCCGTCATTCCGCTCTGAAGCTGGTTCTGC
AGGACGTGATACACGTGGTCTTATCCGCCTACACCAATTCCACAAAGTTGAGATGGTCAAGTTTGCTAAACCAGAAGAAT
CTTACCAAGAGTTGGAAAAAATGACAGCCAACGCTGAAAATATTCTTCAAAAGCTCGGCTTACCATACCGTGTTATCGCC
CTTTGCACTGGCGACATGGGCTTCTCAGCTGCTAAAACTTATGACCTTGAAGTCTGGATTCCAGCTCAAAATACCTATCG
TGAAATTTCATCATGTTCAAATACAGAAGATTTCCAAGCACGTCGTGCTCAAATCCGTTACCGTGATGAGGCTGACAGTA
AGGTCAAACTTCTTCACACCCTTAATGGGTCAGGACTTGCTGTCGGTCGTACCGTAGCAGCCATTTTAGAAAACTACCAA
AACGAAGATGGTTCTGTTACCATCCCTGAAGTACTCCGCCCTTACATGGGTGGCGAAACCGTCATTTCACCTAAATAA

Protein sequence :
MLDLKRIRTDFDAVAAKLKIRGVSEDTLTHLKNLDEKRRALLVQSEELKAERNIASAAIAQAKRQKEDASQQIADMQNVS
ADIKTIDSQLADIDQQVTDIITVLPNTPHDSVPVGADEEDNVEIRRWGTPRDFDFEVKAHWDLGEDLDILDWERGAKVTG
ARFLFYKNLGARLERALYNFMLDEHIKEGYQEIITPYMVNHDSMFGTGQYPKFKEDTFELSDTNFVLIPTAEVPLTNYYR
GEILDGKELPIYFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPEESYQELEKMTANAENILQKLGLPYRVIA
LCTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNTEDFQARRAQIRYRDEADSKVKLLHTLNGSGLAVGRTVAAILENYQ
NEDGSVTIPEVLRPYMGGETVISPK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-177 84