Gene Information

Name : tkt (SDEG_1735)
Accession : YP_002997432.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : -
Position : 1666839 - 1669028 bp
Length : 2190 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGGCCACTGTGTCAACAGGCTTTCTTATATTCAGCGTCAAAAAGAATTCACCAATGATGTCCAAACTAGTTTTTTTCTG
GCAAAATAGAGAAAAAGAATTTAGGGACTTTGGAGGATTTTCTGAAAAAAGCGTCTATTTTTGTGATACAATAGACAATA
GAAAACGTTTAATTTTAGTTGTAATAAACAGAGAGGTTTTACTTATGACATTTGATGCAATTGACCAGTTGGCAGTAAAC
ACTGTCCGCACCCTATCAATGGATGCCATTCAAGCGGCAAATTCTGGACACCCAGGACTTCCAATGGGGGCAGCACCTAT
GGCCTATGTTCTTTGGAATCACTTCATGAACATCAATCCCAAAACAAGCCGTAATTGGTCAAACAGAGACCGTTTTATCC
TATCAGCAGGTCATGGAAGTGCCATGCTTTATAGCTTGTTACACTTAGCTGGTTATGATTTATCTGTAGAAGATTTAAAG
AACTTCCGTCAATGGGGTTCTAAAACACCAGGTCACCCAGAAGTGAACCACACAGACGGTGTCGAAGCAACCACAGGACC
TCTTGGTCAAGGGATCGCAAATGCCGTTGGTATGGCCATGGCAGAAGCTCATCTAGCAGCTAAATTTAACAAACCAGGCT
TTGACATCGTTGATCACTACACCTTTGCTTTGAATGGTGACGGTGACCTTATGGAAGGGGTCAGCCAAGAAGCAGCAAGT
ATGGCAGGACATTTAAAACTTGGGAAATTGGTCTTGCTATATGATTCAAACGACATCTCTCTTGATGGTCCAACCTCTAT
GGCTTTCACAGAAGATGTGAAAGGACGTTTCGAAGCTTATGGTTGGCAACATATCCTTGTGAAAGATGGAAATGATTTAG
AAGAAATTGCAGCTGCTATTGAAGCAGCTAAAGCTGAAACTGAGAAACCAACCATCATCGAAGTCAAAACCATTATTGGT
TTTGGTGCCGAAAAACAAGGAACTTCAGCTGTTCACGGCGCTCCTCTTGGAGCAGAAGGCATTGCTTTTGCCAAAAAAGC
TTACCAATGGACTCATCAAGATTTTGAAGTGCCTGCTGAAGTAACAGAGCACTTTGCTCAAGGACTTCAAGCACGTGGTG
AAAAAGCAGAACAAGCCTGGAATGACTTGTTTGCAGCTTATCAAGCAGAATATCCAGAATTAGCAGCAGAATACCAAAAA
GCCTTTACTAACGAAGCTGCTCAAGTAGAACTTGAAGCGCACGAACTTGGCAGCTCAATGGCGAGTCGTGTTTCTAGCCA
ACAAGCCATCCAACAAATCTCAGAACAAGTAGCCTCTTTCTGGGGTGGATCAGCAGATCTTTCAGCATCTAACAACACAA
TGGTTAAGGCTGAAACAGATTTCCAACCAGGTCACTACGAAGGCCGTAACATCTGGTTTGGCGTTCGTGAATTTGCCATG
GCTGCAGCCATGAACGGTATTGCCCTTCACGGCGGGACACGCGTTTACGGCGGAACCTTCTTTGTCTTCTCAAACTATCT
TCTTCCAGCTGTTCGTATGGCAGCGCTCCAAAACTTGCCAACAGTTTATGTCATGACACATGATTCTATCGCTGTTGGTG
AAGATGGGCCAACGCACGAACCAATTGAACAATTGGCAAGTGTTCGCTCAATGCCTAACTTGAACGTTATTCGTCCAGCA
GACGGTAACGAAACAAATGCTGCTTGGAAACGTGCCATTGCTGAAACAGATCGCCCAACTATGCTTGTATTGACGCGTCA
AAACCTTCCAGTGCTTGAGGGCACAAAAGAATTGGCAGAAGATGGTCTTAACAAAGGAGCTTACATCTTGTCAGAAGCCA
AAGGCGACCTTGATGGTATCTTGATTGCAACAGGTTCAGAAGTGAAACTGGCAATGGATACTCAAGAAGCTCTTGAAGCA
GAAGGCATTCATGTTCGCGTCGTATCTATGCCATCACAAAATATCTTTGACGAACAGTCAGCAGAGTATAAAGAAAGCAT
CCTACCAGCAGCTGTGACTAAACGTCTCGCTATCGAAGCAGGTTCAAGCTTTGGCTGGGCAAAATATGTCGGCCTAGCAG
GAAAAACATTGACCATTGACACTTGGGGTGCTTCAGCTCCAGGAAATCGTATCTTCGAAGAATATGGTTTCACTGTGGCA
AATGCAACTGAGTTATACAAATCACTCTAG

Protein sequence :
MATVSTGFLIFSVKKNSPMMSKLVFFWQNREKEFRDFGGFSEKSVYFCDTIDNRKRLILVVINREVLLMTFDAIDQLAVN
TVRTLSMDAIQAANSGHPGLPMGAAPMAYVLWNHFMNINPKTSRNWSNRDRFILSAGHGSAMLYSLLHLAGYDLSVEDLK
NFRQWGSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAKFNKPGFDIVDHYTFALNGDGDLMEGVSQEAAS
MAGHLKLGKLVLLYDSNDISLDGPTSMAFTEDVKGRFEAYGWQHILVKDGNDLEEIAAAIEAAKAETEKPTIIEVKTIIG
FGAEKQGTSAVHGAPLGAEGIAFAKKAYQWTHQDFEVPAEVTEHFAQGLQARGEKAEQAWNDLFAAYQAEYPELAAEYQK
AFTNEAAQVELEAHELGSSMASRVSSQQAIQQISEQVASFWGGSADLSASNNTMVKAETDFQPGHYEGRNIWFGVREFAM
AAAMNGIALHGGTRVYGGTFFVFSNYLLPAVRMAALQNLPTVYVMTHDSIAVGEDGPTHEPIEQLASVRSMPNLNVIRPA
DGNETNAAWKRAIAETDRPTMLVLTRQNLPVLEGTKELAEDGLNKGAYILSEAKGDLDGILIATGSEVKLAMDTQEALEA
EGIHVRVVSMPSQNIFDEQSAEYKESILPAAVTKRLAIEAGSSFGWAKYVGLAGKTLTIDTWGASAPGNRIFEEYGFTVA
NATELYKSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 2e-134 51
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-131 49