Gene Information

Name : nrdE.2 (SDEG_1423)
Accession : YP_002997132.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1374513 - 1376672 bp
Length : 2160 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGAGTCTCAAAGATCTTGGCGATATTTCTTATTTCCGCCTAAATAATGAAATTAACCGTCCTGTTGGCGGTAAAATTCC
ACTCCATAAAGACAAAGAAGCTTTAGAAGCTTTTTTCACTGAAAATGTGCTTCCAAACACCATGTCTTTTGCCTCCGTTA
CGGAAAAAATTGAATATTTAATCTCAAATGATTACATTGAATCAGCTTTTATTCAGAAATACCGTCCTGAATTTATTACT
GAATTAGCTGACGTCATCAAGGCAGAAAATTTCCAATTCAAATCGTTCATGGCAGCTTATAAATTTTATCAGCAGTATGC
CTTAAAAACAAATGATGGAGACTATTATTTAGAAAGCCTTGAAGACCGTGTTATGTTTAATGCTCTGTATTTTGCAGATG
GTAACGAAGCCCTTGCTAAAGACTTAGCCATTGAAATGATCAACCAGCGCTACCAACCGGCAACTCCTTCTTTTTTAAAT
GCTGGTCGAAGCCGTCGTGGTGAATTAGTGTCTTGTTTCTTGATTCAAGTGACAGATGACATGAACTCTATCGGACGTTC
CATTAACTCTGCCTTGCAATTATCTCGTATCGGTGGAGGAGTTGGTATTACCCTTTCTAACCTGCGTGAAGCTGGGGCAC
CAATTAAAGGCTATGCTGGTGCAGCTTCAGGGGTTGTTCCTGTTATGAAACTGTTTGAAGATAGTTTTTCTTATTCAAAT
CAACTTGGACAACGTCAAGGAGCTGGTGTTGTTTACCTAAATGTTTTCCATCCGGATATTATCGCTTTCTTATCTACTAA
AAAAGAAAATGCTGATGAAAAGGTGCGTGTGAAAACCTTGTCATTGGGAATTACCGTTCCTGATAAATTCTACGAATTAG
CTCGTAAAAATGAGGACATGTATCTCTTTAGTCCTTATAATGTTGAAAAAGAATATGGCATTCCCTTTAACTATCTCGAC
ATCACCAACATGTACGATGAGTTAGTGGCTAATCCTAAAATTACTAAGACTAAAATCAAAGCTCGGGATCTTGAAACAGA
GATTTCAAAACTGCAACAAGAATCTGGCTACCCTTACATTATCAATATTGATACTGCTAATAAAGCTAATCCTATCGATG
GAAAAATCATCATGAGCAACTTGTGTTCTGAAATTTTACAAGTTCAGACACCTAGCCTTATCAATGATGCGCAAGAGTTC
TTACAAATGGGAACTGATATCTCATGTAACCTCGGCTCAACTAATATCCTTAACATGATGACATCTCCAGATTTTGGACG
TTCTATTAAAGCCATGACACGTGCCTTAACCTTCGTGACCGACTCATCAAGCATCGAAGCTGTCCCAACCATTAAACATG
GCAATAGCCAAGCTCATACTTTCGGTCTTGGGGCAATGGGACTTCATTCTTACTTAGCTCAACATCATATTGAATATGGT
AGCCCAGAATCCGTCGAATTCACTGATATTTATTTCATGCTCATGAACTATTGGACTCTCGTCGAATCCAATAACATCGC
TCGTGAACGCCAAACCACCTTTGTTGGTTTTGACAAGTCAAAATATGCTGATGGAACCTACTTTGACAAATATGTCACAG
GTCAATTTGTTCCAAAATCTGATCTGGTGAAAGACCTGTTCAAGGACCATTTTATTCCGCAAGCTTCAGATTGGGAGGCT
CTTCGCGACGCCGTTCAAAAAGATGGTCTTTATCATCAAAACCGTCTTGCAGTTGCTCCAAATGGCTCTATTTCTTATAT
CAATGACTGCTCTGCTTCTATTCACCCCATCACACAACGCATCGAAGAGCGTCAAGAAAAGAAAATTGGTAAGATTTACT
ACCCAGCAAATGGCTTGTCAACGGATACTATCCCTTATTACACGTCTGCGTACGATATGGACATGCGTAAGGTTATCGAT
GTCTATGCCGCTGCGACCGAACATGTGGATCAAGGTTTGTCTTTAACCTTATTCCTTCGTAGTGAGTTGCCTATGGAGCT
TTATGAGTGGAAAACAGAAAGTAAGCAAACCACTCGTGATCTTTCTATTTTACGAAATTACGCTTTCAATAAAGGTATCA
AATCTATCTACTATATCCGCACCTTTACGGATGACGGGGAAGAAGTTGGTGCAAACCAATGTGAGTCTTGTGTTATTTAA

Protein sequence :
MSLKDLGDISYFRLNNEINRPVGGKIPLHKDKEALEAFFTENVLPNTMSFASVTEKIEYLISNDYIESAFIQKYRPEFIT
ELADVIKAENFQFKSFMAAYKFYQQYALKTNDGDYYLESLEDRVMFNALYFADGNEALAKDLAIEMINQRYQPATPSFLN
AGRSRRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYAGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGITVPDKFYELARKNEDMYLFSPYNVEKEYGIPFNYLD
ITNMYDELVANPKITKTKIKARDLETEISKLQQESGYPYIINIDTANKANPIDGKIIMSNLCSEILQVQTPSLINDAQEF
LQMGTDISCNLGSTNILNMMTSPDFGRSIKAMTRALTFVTDSSSIEAVPTIKHGNSQAHTFGLGAMGLHSYLAQHHIEYG
SPESVEFTDIYFMLMNYWTLVESNNIARERQTTFVGFDKSKYADGTYFDKYVTGQFVPKSDLVKDLFKDHFIPQASDWEA
LRDAVQKDGLYHQNRLAVAPNGSISYINDCSASIHPITQRIEERQEKKIGKIYYPANGLSTDTIPYYTSAYDMDMRKVID
VYAAATEHVDQGLSLTLFLRSELPMELYEWKTESKQTTRDLSILRNYAFNKGIKSIYYIRTFTDDGEEVGANQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 3e-176 51