Gene Information

Name : pyk (SDEG_1094)
Accession : YP_002996807.1
Strain : Streptococcus dysgalactiae GGS_124
Genome accession: NC_012891
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1072647 - 1074149 bp
Length : 1503 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAATAAACGCGTAAAAATCGTTGCAACACTTGGTCCTGCGGTTGAAATCCGTGGTGGTAAAAAATATGGAGAAGATGG
CTACTGGGCTGGTCAACTTGATGTTGAAGAATCTGCAAAAAAAATCGCTGAATTAATTGAAGCTGGTGCGAATGTTTTCC
GTTTCAATTTCTCACATGGTGACCACAAAGAACAAGGTGACCGTATGGCAACTGTCCGCCTTGCAGAAGAAATTGCTCGT
CAAAAAGTTGGTTTCCTTTTGGATACTAAAGGTCCTGAAATGCGTACGGAATTGTTTGCAGATGATGCTAAAGAGTTCAG
CTATGTTACTGGAGAAAAAATCCGTGTAGCGACTACACAAGGTATTCAATCAACTCGCGATGTTATTGCTTTGAACGTTG
CTGGTAGCCTTGACATCTACGATGAAGTAGAAGTAGGTCATACTATTCTTATCGATGATGGTAAGCTTGGTTTGAAAGTG
ATCGACAAAGATATCGCAACACGTCAATTTATTGTTGAAGTAGAAAACGACGGTATTATTGCTAAACAAAAAGGTGTTAA
TATCCCTAACACTAAAATTCCTTTCCCAGCACTTGCGGAACGCGACAATGCTGATATCCGTTTTGGTCTTGAACAAGGAC
TTAACTTTATTGCAATCTCATTTGTTCGTACAGCCAAAGACGTTGAGGAAGTTCGTGAAATCTGTCGCGAAACTGGTAAC
GACCATGTTCAATTATTTGCTAAGATTGAAAACCAACAAGGTATCGATAATCTTGATGAAATCATCGAAGCTGCTGATGG
TATCATGATTGCACGTGGCGACATGGGTATCGAAGTACCATTTGAAATGGTTCCAGTTTTCCAAAAAATGATTATCACTA
AAGTGAATGCAGCTGGTAAAGCAGTTATCACAGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCGACACGC
TCTGAAGTATCTGACGTCTTCAATGCTGTTATCGATGGTACTGATGCAACAATGCTTTCAGGAGAGTCAGCTAATGGTAA
ATACCCAGTTGAATCTGTTCGTACAATGGCGACTATTGATCGTAATGCACAAACTCTTCTTAACGAATATGGTCGTTTAG
ATTCATCTGCATTCCCACGTACAAACAAAACTGATGTAATTGCTTCAGCGGTTAAAGATGCAACTCATTCAATGGACATC
AAACTTGTGGTTACAATTACCGAAACTGGTAATACTGCACGTGCGATTTCTAAATTCCGTCCAGATGCGGACATCTTAGC
TGTAACATTTGATGAAAAAGTACAACGTGCATTGATGATTAACTGGGGTGTTATTCCAGTTCTTGCTGAAAAACCTGCAT
CTACTGATGACATGTTTGAAGTAGCAGAACGTGTGGCTCTTGAAACTGGTTTGGTTCAATCTGGTGATAACATTGTTATC
GTTGCAGGTGTTCCAGTTGGTACTGGTGGAACAAACACAATGCGTGTTCGTACTGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIAR
QKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGN
DHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVALETGLVQSGDNIVI
VAGVPVGTGGTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-81 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-81 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-81 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-81 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_002996807.1 pyruvate kinase VFG0479 Protein 7e-82 43