Gene Information

Name : hemC (Desal_0642)
Accession : YP_002990247.1
Strain : Desulfovibrio salexigens DSM 2638
Genome accession: NC_012881
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 698263 - 699189 bp
Length : 927 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAGAAAAATTACCATCGCAACACGCGGCAGCAAACTTGCCCTCTGGCAGGCCAACCATATTTCCGACCTTCTGCGTGA
AGAGTACCCCGGAATCGAAGTTCAACTGCTCAAGATCAAAACCAAGGGCGATAAGATTCTGGACGTTCCGCTGGCAAAAG
TGGGCGGCAAGGGCCTTTTCGTAAAAGAAATCGAAGAAGCACTGCTTGATGGCCGTGCCGACCTCGCAGTTCACAGCATG
AAGGACGTTCCCACCGAACTTCCTGAAGGCCTTGAAGTGGGCATCATTCCCCCGCGTGAAGCAGAAACCGACACCCTGCT
TTCCGTTAAATACGATTCTCTAAAAGACCTGCCTGCCGGTGCTGTAGTCGGTACCAGCAGCCTGCGCCGCCAGTCTCAGG
TTCTGGCACTGCGTGATGACCTTAAAATCGAATCCCTGCGCGGTAACCTTGATACCCGAGTAGGAAAACTTCTCAACGGT
GAATTCGATGCTATCGTTGTTGCAACCGCAGGACTGAACAGACTCAAACTTTCCGCTCCCAAAAGCGAAATCCTCGGGCC
TCCGACCTTCCTGCCCGCAGTGGCACAGGGTGCTCTGGGCATCGAATACCGCATTGAGGACACCGAAATTCAGGACATTC
TCGCATTCCTGCATGACGAAATGACTGCACGTCAGGTCAAAGCAGAACGCGGTTTCCTGACCGGTCTCGACGGCGGCTGT
CAGGTTCCCATCGCAGCTTGGTCCCAGCTTGAAAGCGATCAGGTCAAGCTGACCGGATTTGTTGCTGACATCGACGGTTC
CAGCCCCATCCGCATGGAGAAGACAGGACCGGCTGAGGATGCATGGGACATCGGCCTTGCCCTTGCTGAAGAAGTTCTGG
CAGCAGGAGCAAAAGAAATTCTCGATCGCGTTTACGACAAGTGCTAA

Protein sequence :
MRKITIATRGSKLALWQANHISDLLREEYPGIEVQLLKIKTKGDKILDVPLAKVGGKGLFVKEIEEALLDGRADLAVHSM
KDVPTELPEGLEVGIIPPREAETDTLLSVKYDSLKDLPAGAVVGTSSLRRQSQVLALRDDLKIESLRGNLDTRVGKLLNG
EFDAIVVATAGLNRLKLSAPKSEILGPPTFLPAVAQGALGIEYRIEDTEIQDILAFLHDEMTARQVKAERGFLTGLDGGC
QVPIAAWSQLESDQVKLTGFVADIDGSSPIRMEKTGPAEDAWDIGLALAEEVLAAGAKEILDRVYDKC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 9e-65 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 9e-65 52