Gene Information

Name : Desal_2732 (Desal_2732)
Accession : YP_002992325.1
Strain : Desulfovibrio salexigens DSM 2638
Genome accession: NC_012881
Putative virulence/resistance : Unknown
Product : HsdR family type I site-specific deoxyribonuclease
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : 3.1.21.3
Position : 3004784 - 3007915 bp
Length : 3132 bp
Strand : -
Note : KEGG: ecw:EcE24377A_0289 HsdR family type I site-specific deoxyribonuclease; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family; PFAM: protein of unknown function DUF450; type III restriction protein res subunit; SMART: DEAD-like helicase

DNA sequence :
ATGATCAATGAAGCCGCACTGGAAAAGCTAGCCATAAGCTGGTTTGAGGATGAAGGATACGAAAATCACCACGGCCCGGA
CCTGAACCCGGAATCCGACGGCAGCGGTGAGCGGTCCAGTTTTGATGATGTGCTGCTTCTATCCCCCCTTCGTTCTGCCG
TCTCCTGCATCAACCCACAGCTTCCTTCCTCGGCGGTTGATGATGTTATCCACCAGCTTACAACCCTTTCCCATCCTGTA
TCAGTTAAAGCCAACCAATTGTTCCACCGCTTGCTACGCAACGGTCTGGATGTGTCGTACAAAAGAGATGGCGAGACCAT
AGCTGATAAGGCTTTTCTGATTGATTTTCAGGAATGGCAGAACAATATATTCTGGGTTGTGGATCAACTGACTTTGCAGG
GCACCAAGGATAAACGGCGACCTGATTTGATTGTGTATGTGAATGGCTTGCCGTTGGCTGTGATTGAGCTGAAATCTCCG
GTTGATGATTCCGTCGGTGTGGATGAAGCTTTCAATCAGTTGCAGACCTATAGGCATGAGCTGCCGGACCTCGCCATGTT
CAACGAGGCTTTGATTGCATCTGACGGGATCAAGGCACGTGTAGGTTCGCTGACCGCAAGCCGTGAATGGTTTCTGCCGT
GGCGTTACCGTAAATCAGAGGATGATCGCCCTTCATTTGAATATGAGCTTAAAAACGTTGTCGAAGGCTTTTTTGACCGG
AAGCTGTTTCTTGAATATGTGCGCGATTTTGTTCTGTTTGAGTCGGATGATACCAGCACAATTAAGAAGATTGCCGGATA
CCACCAGTTCCACGGGGTGCGTCATGCGGTGGAGGCAATTGTTCAGGCGTCATCTGCTGCGGCATCGGATGAACAGCGAG
GGCGCGGGGGCGTCATCTGGCACACTCAGGGATCGGGAAAGTCGATTTCTATGTGTTGCCTTGCCGGAAAGCTGATCCGC
CATCCTGAGCTTACTAACCCAACCTTAGTGGTGGTGACCGACAGGAACGATCTGGATGGTCAGCTTTACGAGACTTTTTG
TAAGGCCGGAGACCTGTTGAGCGATACCCCTGTACAGGTGGAAGACCGCACATCGCTGCGAAAGGTGCTTAATGAGCGGC
AGTCCGGCGGGATAATTTTTACCACGATCCAGAAATTTTCACTCAGTGACGGTGAAACTGTATTTCCCGCTTTGTCGGAT
CGGCGCAATATTATTGTTATTGCTGATGAGTGCCACCGTTCGCAATATGGCTTCCAGTCTAAGCTCGACGAGAAGAAGGG
AGCTTTCACTGTTGGGTATGCTCAGCATATCCGGGATGCGCTTCCGAATGCGACTTTTACCGGATTTACCGGAACCCCGG
TTTCGCTGGAAGATAAGGATACGCAGGCGGTATTTGGTGAGTACGTCAGTATCTATGATATCGAACAGGCCCAGCAGGAC
GGGGCTACTGTTCCGCTGTTCTATGAAAGTCGGCTGGCAAAGCTGGATCTGAACAAGGAAGAGCTGCCAGTCATCGATGA
TACAGTTGATGAGCTAACCGAAGATGAGGAAAGCGCACAGGCTGAACGTACCAAGGGGCGTTGGGCAGCACTTGCGAAGC
TTGTCGGTTCTGAGCCAAGGCTTAAGCAGATTGCAGAAGATTTGGTGCAGCATTTTGAAGCACGGTTGCAGGTCATCGAC
GGCAAGGCCATGATTGTCTGCATGAGCCGTGAAATCTGCGTGAAGATGTTTGATGCGCTAACAGCTATTCGTCCTGAATG
GACCGGATCAAAGATGAGTGACGGCACTTATGATCCTGCGGACGGAGGCATAAGAATTATTATGACCTCGAATGCTGCTG
ATCCTGAATCTATGCAGAATCACAGTTATAGCAAGCAGCAGAAAAAGGCACTTGAGAAGCGGTTTAAAGATCCTGCCGAT
CCGTTAAAAATAGTAATTATCCGTGATATGTGGCTGACTGGGTTTGATGCTCCGTGCGCCCATACCATGTACATCGATAA
GCCCATGAAGGCTCACAACCTGATGCAGGCCATCGCTCGTGTTAACCGCGTGTTCAAGGGTAAGCCGGGTGGATTGGTTG
TAGACTATATAGGCATTGCAAGTGAGCTTAAAAATGCGCTTCATACTTACACAAATAGCGGTGGGCGTGGTGGTAGGCCG
ACAATTGATGTGACCGAGGCTTTGTTTATTTTGAAAGAGAAGTTGCAGGTCGCCCGTGATATTTTCCATGAGTTCGACTA
TTCGGAGTATGCCACCAAGGCCGTGGAACTACTGCCGTCTGCCGCTGATTATGTAGTTGCCAACGAGAACCGCAAGAAAG
AGTTTTTTGATGTCGTGGTCGCCATGACACGCGCACAGGCCCTATGTGGCACTCTAGACGAAGCTGTGGCGTTTCGGGAT
GAGATCACGTTCTTTCAGGCCGTGAAGATGTTTATCTCCAAGGCCACTAAGCCGAAGAAGAAGTTGTCGCAGCAGGAAAA
GGAAGCTGTTCTGAATCAATTGCTGGCAAAGGCAGTTGTTCCTGAAGGTGTGGACGATATTTTCGCTTTGGCTGGACTTG
ATAAGCCTGACATCTCGATTTTATCAGATGAGTTTCTGGAAGACGTGCGTCATATGGAGCACCGCAATCTTGCCGTTGAG
CTGCTACAAAAGTTGATTAATGACGAGGTCCATTCAAAGTCCCGCAGAAACGAAACACAGCGTAAGAAGTTCTCAGAGAG
GCTTAAAGCGTCACTTACAAAATATCGTAACAGGGCCATTGAGACAGCTCAGGTCATTGAAGAAATGATACAGCTGGCTA
AAGAGCTGAACGAAGCCCTTAAGCGCGGAGAAAAGCTGGGGCTGAATTCGTCAGAAATAGCATTCTATGATGCGCTTGAG
CTAAACGAGTCTGCTGTTCGTGACTTGGGTGATGAGGTGCTTAAAGCCATCGCCCGTGAGTTGACGCAGAAGTTAAGAAA
CAGCGTTACCGTGGATTGGCAGCATAAAGAGTCTGTACGCGCTAAAATGAGAAATCTGGTTCGCCGTATACTTAAGAGAT
ACAAGTATCCGCCGGATGCACAGAAAGAAGCCGTAGAGAAGGTCTTGTCGCAGGCTGAAGAACTGGCGGATGAGTGGAGT
GAGGAAAGTTAA

Protein sequence :
MINEAALEKLAISWFEDEGYENHHGPDLNPESDGSGERSSFDDVLLLSPLRSAVSCINPQLPSSAVDDVIHQLTTLSHPV
SVKANQLFHRLLRNGLDVSYKRDGETIADKAFLIDFQEWQNNIFWVVDQLTLQGTKDKRRPDLIVYVNGLPLAVIELKSP
VDDSVGVDEAFNQLQTYRHELPDLAMFNEALIASDGIKARVGSLTASREWFLPWRYRKSEDDRPSFEYELKNVVEGFFDR
KLFLEYVRDFVLFESDDTSTIKKIAGYHQFHGVRHAVEAIVQASSAAASDEQRGRGGVIWHTQGSGKSISMCCLAGKLIR
HPELTNPTLVVVTDRNDLDGQLYETFCKAGDLLSDTPVQVEDRTSLRKVLNERQSGGIIFTTIQKFSLSDGETVFPALSD
RRNIIVIADECHRSQYGFQSKLDEKKGAFTVGYAQHIRDALPNATFTGFTGTPVSLEDKDTQAVFGEYVSIYDIEQAQQD
GATVPLFYESRLAKLDLNKEELPVIDDTVDELTEDEESAQAERTKGRWAALAKLVGSEPRLKQIAEDLVQHFEARLQVID
GKAMIVCMSREICVKMFDALTAIRPEWTGSKMSDGTYDPADGGIRIIMTSNAADPESMQNHSYSKQQKKALEKRFKDPAD
PLKIVIIRDMWLTGFDAPCAHTMYIDKPMKAHNLMQAIARVNRVFKGKPGGLVVDYIGIASELKNALHTYTNSGGRGGRP
TIDVTEALFILKEKLQVARDIFHEFDYSEYATKAVELLPSAADYVVANENRKKEFFDVVVAMTRAQALCGTLDEAVAFRD
EITFFQAVKMFISKATKPKKKLSQQEKEAVLNQLLAKAVVPEGVDDIFALAGLDKPDISILSDEFLEDVRHMEHRNLAVE
LLQKLINDEVHSKSRRNETQRKKFSERLKASLTKYRNRAIETAQVIEEMIQLAKELNEALKRGEKLGLNSSEIAFYDALE
LNESAVRDLGDEVLKAIARELTQKLRNSVTVDWQHKESVRAKMRNLVRRILKRYKYPPDAQKEAVEKVLSQAEELADEWS
EES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 58
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 45
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 45
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 45