Gene Information

Name : guaA (Desal_1552)
Accession : YP_002991153.1
Strain : Desulfovibrio salexigens DSM 2638
Genome accession: NC_012881
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1698824 - 1700371 bp
Length : 1548 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGCAGCACGATAATAAAGTAATTATTCTGGATTTCGGGTCTCAGTTTACTCAGCTGATCGCTCGTAGAATCCGTGAAGC
GGGTGTGTATTCCGAAATTCACCCCTGTAATGTTGATCCCCAGAAGATTAAGGATCTCAATCCCGGTGCGCTGATTCTTT
CCGGTGGACCTTCCTCTGTTCTGGAAGATGAATCTCCGCAGCTTGATCCTTCCCTGCTGGAACTGGGCGTTCCCGTGCTT
GGCATCTGCTACGGCATGCAGCTCATGACCAACGATCTCGGCGGTCGCGTTGTTTCTTCCGAGGACCGTGAATACGGCCG
TGCGGAATTCAAAGGCGATTCCAGCTGCACTATTTTTGAAGGAATCGAAGACATCGAAAAGCTCACCGTATGGATGAGCC
ACGGTGACCGTGTTGAAGCAATCCCCGAGGGATTTAAAGTTTGCGGTACTACCGAGTCTATTCCTTTCGCAGCAATGGCT
AACGAAGAAAAGAAAATGTACGCACTCCAGTTCCACCCCGAAGTGGCACACACCGAGAGCGGTACCACCATCATCAATAA
CTTTGTTTTCAAAGTTGCAGGCCTCAAAGCTGATTGGACCATGTCCTCTTTCGTAGAGAACTGCATCGAGGAAATGCGCG
AAAAAATCGGTGACAACCAGGTGGTTCTCGGTCTTTCAGGCGGTATTGACTCCACTGTTGTTGCTGTTCTTCTTCACAAA
GCCATCGGCAAGCGTCTGCACTGCATCTTCGTAGATAACGGTCTGCTGCGTATGCACGAGCGTGAAGAAGTTATCGGCTT
CCTCGAAGAGCACTTCGAACTCAACGTTAAGTGCGTTGATTCCGCAGAACTCTTCCTTGATAAACTCAAAGGTGTTGAAG
ATCCCGAGAAGAAGCGCAAGCTCATCGGTTACACCTTCATTGATGTTTTCAACGAAGAAGCAAGCGCACTCAAGGATGTA
AAATTCCTCGCACAGGGTACTCTTTACCCCGATGTTATTGAGTCCGAATCCTTCAAAGGCCCCTCCGCGGTCATCAAGTC
CCACCACAACGTTGGCGGACTGCCCGAAGATATGGATCTCGATCTGGTTGAGCCTCTGCGTGAACTTTTCAAAGATGAAG
TACGTAAGGTTGCTTACGAGCTTGGTCTGCCCGAGTTCATTATTTGGCGTCAGCCCTTCCCCGGTCCGGGTCTTGCTATC
CGTGTTCTGGGTGAAATCACTGAAGAGCGTCTTGAAATCCTGCGTCAGGCTGACAAGATTGTACAGAACGAAATGCATGC
CTCCGGCTGGTACCGCAAGGTATGGCAGGGCTTCGCTGTTCTGCTGCCTCTCAAGACTGTCGGCGTAATGGGTGATGACC
GTACTTACGAGCACGTCATTGCACTGCGTATCGTAGACAGCATCGATGCTATGACCGCTGACTGGTCCCGCATCCCCAAC
GATATCCTCGCACGTATGTCCAACAGGATCATCAACGAGGTTAAAGGTGTTAACCGCGTGGTTCTGGATATTTCCTCCAA
GCCGCCGGCAACCATCGAATGGGAATAA

Protein sequence :
MQHDNKVIILDFGSQFTQLIARRIREAGVYSEIHPCNVDPQKIKDLNPGALILSGGPSSVLEDESPQLDPSLLELGVPVL
GICYGMQLMTNDLGGRVVSSEDREYGRAEFKGDSSCTIFEGIEDIEKLTVWMSHGDRVEAIPEGFKVCGTTESIPFAAMA
NEEKKMYALQFHPEVAHTESGTTIINNFVFKVAGLKADWTMSSFVENCIEEMREKIGDNQVVLGLSGGIDSTVVAVLLHK
AIGKRLHCIFVDNGLLRMHEREEVIGFLEEHFELNVKCVDSAELFLDKLKGVEDPEKKRKLIGYTFIDVFNEEASALKDV
KFLAQGTLYPDVIESESFKGPSAVIKSHHNVGGLPEDMDLDLVEPLRELFKDEVRKVAYELGLPEFIIWRQPFPGPGLAI
RVLGEITEERLEILRQADKIVQNEMHASGWYRKVWQGFAVLLPLKTVGVMGDDRTYEHVIALRIVDSIDAMTADWSRIPN
DILARMSNRIINEVKGVNRVVLDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-140 56
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-140 56
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 4e-140 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-128 53