Gene Information

Name : Rpic12D_0577 (Rpic12D_0577)
Accession : YP_002980554.1
Strain :
Genome accession: NC_012856
Putative virulence/resistance : Virulence
Product : polysaccharide biosynthesis protein CapD
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1086
EC number : -
Position : 611443 - 613326 bp
Length : 1884 bp
Strand : +
Note : PFAM: polysaccharide biosynthesis protein CapD; Male sterility domain; dTDP-4-dehydrorhamnose reductase; NAD-dependent epimerase/dehydratase; KEGG: cvi:CV_4115 polysaccharide biosynthesis protein

DNA sequence : 
ATGTACCTCCAGAAGATTTCCGAGATGTCGCGCCAGAAGAAGATTCTGCTCATGCTGGCGCTCGACTTTTTGTTGCTGCC
ACTGTCCCTTTGGTCGGCGGTAGGCCTGCGTACAGACCACTGGGCGGTGGGTTCTCAATACCCAATTGGCGTTTACTTCA
TCGCGTCGGCGGTTGCGATTCCAGTCTTCATCCGCATGGGGCTTTATCGATCCGTGGTGCGGTATATGGAAGATCGAGCG
ATCCTGACGATCATCGCCGCGGTGTCGATCTCGATCACCATCTTCGGTTCGCTCATCTATTTCCTCGGTCTGTCCAATGT
GCCCCGAGGAGCGCTGCTAATTTACTGGTTGCTAGCAATTTTCTATATCGTTTGCAGTCGGTTCTTTGCGCGTGCAGCGT
TTCGCATGTTGCCCGGATTCCATCGCCAACGACAGAAGGTCATCATCTACGGTGCCGGTGAAGCAGGCCGGCAACTTGCG
GTGGCGCTGCGTGCCGGCCCCGACTATGACCCGATTGGTTTTGTGGATGACGACCCTGCCAAAGTGAAGCTCAACATTGG
GGGGATATCAGTCCACCAAGCTGAACAGCTCCCGGCTTTGATCAAGGACCTTGGCGTCAGCCAGGTACTGCTGGCCATAC
CCTCCGCGTCGCGCGGGCGTCGTATTGAAATCGTGAACGCGCTCGAGCCGTTGGCGGTGGAGGTTCGGGTTGTGCCAGGT
ATGGCAGACCTGGTGTCCGGCGAGGTGCATCTTGCCGATGTGCGCGAGGTCGAGATCGACGAATTGTTGGGGCGCGAGGT
GGTGGCCCCACGCCGTGACCTGCTACGTCAGAGCATCGCAGGCAAGTGCGTGATGGTGACTGGAGCGGGAGGGTCGATCG
GATCGGAGTTGTGTCGCCAGATCATCAAGAACGAGCCCGTGCAAGTGGTGTTGTATGAGCAATCAGAGTTCTTTCTCTAC
AGCATCGAGTATGAACTGAAGCAAATCATTGCTGCCCAGGGTCTTGCGATCGAATTGGTGCCGGTGCTGGGTTCAGTGCT
GAACGGCGACAGGTTGTTCAGCATCATGTCCAAGTACAACGTGCAGACCATTTATCACGCGGCTGCATACAAGCATGTGC
CGATCGTTGAGTTCAATATGACCGAAGGCATATTGAATAACACTGTGGGCACGCGGGTAGCGGCGGAGGCGGCAATGCGT
GCCAACGTTGAATCGTTCGTACTGATCTCAACGGATAAGGCGGTGCGGCCGACCAACGTCATGGGCGCAAGCAAACGAAT
GGCCGAGCTTTGCTTGCAAGCATTGGCCCAGGATTGCGCCAACACTCGTTTCAGCATCGTTCGCTTTGGTAACGTACTCG
GCTCCAGTGGTTCCGTTGTGCCACTGTTCAGGAAGCAGATCGCCGCAGGCGGCCCCGTCACCGTGACGCATCAGGACATC
ACGCGCTACTTCATGACGATACCCGAGGCTGCGCAATTGGTGATTCAGGCTGGAGCAATGGGTGGGGAGGGTGAGGTCTT
TGTCCTGGACATGGGGCAGCCGGTCAAGATTGTCGATCTGGCGCGCCGCATGATCCACTTGAGCGGGTTCCAGGTTCGTG
ATGGTGCCAACCCCGCTGGAGATATCGAAATCCAGTTCACCGGGCTGCGTCCTGGGGAAAAACTTTACGAAGAACTGTTG
ATCGGAGACGCCGTAAGTGGCACTGATCATCCGCTCATCATGAAGGCGGACGAGTCGTGCCTCAACCACGAAGTGCTCGA
CGAGTGCATGACGCGGCTGATACACGCCTGCAATGCCAATGACTACGAAACAATTCGGAATATTCTTCTGGAGTGCGTAT
CGGGGTTCCGCCCAGACCACGATATCAAAGACCACCTGTACTGA

Protein sequence : 
MYLQKISEMSRQKKILLMLALDFLLLPLSLWSAVGLRTDHWAVGSQYPIGVYFIASAVAIPVFIRMGLYRSVVRYMEDRA
ILTIIAAVSISITIFGSLIYFLGLSNVPRGALLIYWLLAIFYIVCSRFFARAAFRMLPGFHRQRQKVIIYGAGEAGRQLA
VALRAGPDYDPIGFVDDDPAKVKLNIGGISVHQAEQLPALIKDLGVSQVLLAIPSASRGRRIEIVNALEPLAVEVRVVPG
MADLVSGEVHLADVREVEIDELLGREVVAPRRDLLRQSIAGKCVMVTGAGGSIGSELCRQIIKNEPVQVVLYEQSEFFLY
SIEYELKQIIAAQGLAIELVPVLGSVLNGDRLFSIMSKYNVQTIYHAAAYKHVPIVEFNMTEGILNNTVGTRVAAEAAMR
ANVESFVLISTDKAVRPTNVMGASKRMAELCLQALAQDCANTRFSIVRFGNVLGSSGSVVPLFRKQIAAGGPVTVTHQDI
TRYFMTIPEAAQLVIQAGAMGGEGEVFVLDMGQPVKIVDLARRMIHLSGFQVRDGANPAGDIEIQFTGLRPGEKLYEELL
IGDAVSGTDHPLIMKADESCLNHEVLDECMTRLIHACNANDYETIRNILLECVSGFRPDHDIKDHLY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cap1D AAA64643.1 type 1 capsule synthesis gene Virulence SCCcap1 Protein 6e-85 45
SSP0063 YP_300153.1 capsular polysaccharide biosynthesis protein Not tested SCC15305cap Protein 2e-81 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Rpic12D_0577 YP_002980554.1 polysaccharide biosynthesis protein CapD VFG0029 Protein 4e-117 50
Rpic12D_0577 YP_002980554.1 polysaccharide biosynthesis protein CapD VFG1300 Protein 3e-82 45