Gene Information

Name : tpx (Rpic12D_2625)
Accession : YP_002982568.1
Strain :
Genome accession: NC_012856
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2762501 - 2763001 bp
Length : 501 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGGCAAACGTGACCCTTGGCGGCAACCCGATCGAAGTCGGCGGCCAATTCCCGACCGCAGGCTCGAAGGCCCCGGCATT
CACGCTGGTCGGCGCAGACCTGAAAGACGTGTCGCTCGCTGACTTTGCCGGCAAGCGCAAGGTCCTGAACATCGTGCCGA
GCCTGGACACCCCGGTGTGCGCCACCTCCACGCGCAAGTTCAACGAAGCCGCTGCCAAGCTGGACAACACGGTCGTGCTG
TCCATCTCTGCCGACCTGCCGTTCGCAGCCGGCCGCTTCTGCACCACCGAAGGCATCGCGAATGTGAAGCCGCTGTCGAC
CTTCCGCGACAAGGGTTTCAAGCAAGCCTACGGCGTCGACATCACGTCGGGCCCGCTGGCTGGCGTGACCGCCCGCGCCG
TGGTCGTGCTCGACGCCGACGACACCGTCCTGTACTCGCAACTCGTGCCCGAGATCAAGGACGAGCCGAACTACGACGCG
GCCCTGGCTGCGCTGAAGTAA

Protein sequence : 
MANVTLGGNPIEVGGQFPTAGSKAPAFTLVGADLKDVSLADFAGKRKVLNIVPSLDTPVCATSTRKFNEAAAKLDNTVVL
SISADLPFAAGRFCTTEGIANVKPLSTFRDKGFKQAYGVDITSGPLAGVTARAVVVLDADDTVLYSQLVPEIKDEPNYDA
ALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-30 47
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 8e-31 47
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-30 47
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 6e-31 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_002982568.1 thiol peroxidase VFG0087 Protein 2e-31 47