Gene Information

Name : hemC (Rpic12D_2166)
Accession : YP_002982112.1
Strain :
Genome accession: NC_012856
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2305310 - 2306326 bp
Length : 1017 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTCTTCCAACGCCCGCCCGACTTCCCGTCAATCCCAGCTTGCTACGACTCCTGCAGCCCAGGCGCCGACCAAGCTGGT
CATCGCCTCGCGCGAAAGCCGGCTCGCCCTCTGGCAAGCCGAACACGTGCGTGCTGCATTGCAAAAATACTATCCCGCGT
GCGACGTGTCCATCCTTGGAATGACCACGCGCGGCGACCAGATTCTCGACCGCTCCCTCGCCAAGGTGGGGGGGAAAGGT
TTGTTCGTGAAGGAATTGGAGGTCGCGCTGGCCGAAGGGCGTGCCGATCTGGCCGTGCATTCGCTCAAGGATGTGCCGAT
GCAATTGCCGGAAGGCTTTGCGCTATCCACCATTCTCGAACGCGAAGACCCGCGCGATGCCTTTGTTTCCAACGATTACG
CCGATCTGGCCTCGCTGCCGGCCGGCGCGGTCGTCGGTACGTCCAGCCTGCGCCGCGAGGCATCGCTGCGGGCGCGGTTT
CCGCATCTGGTCATCCAACCGCTGCGGGGCAACCTCGATACGCGTCTCGGCAAGCTTGACCGCGGCGACTACGCCGCCAT
CATCCTGGCCGCCGCCGGGCTCAGGCGCCTTGGGCTGGCTGATCGCATCCGCTCGACCATCGCGCCAGAAGAATCGCTAC
CGGCAGCAGGGCAAGGCGCGCTCGGCATTGAAATTCGCGCGGATCGTGAAGAGGTGCGCGCGTGCCTCGCGCCGCTGCAC
GATGCGCCGACAGCGCTGGCTGTAACCGCCGAGCGCGCCGTTTCCCGCATTCTGGGCGGTTCATGCCAGGTGCCGCTGGC
CGCGTTCGCGCAGTGGTCGGGCGCAGGCACCTTGCGCCTGCGTGCCTTTGTGGCGTCGCAGGACGGCACCCGCAAACTTG
CCGCAGATGGCGAAGCCACGCCATCCACGCTGGCCGATGCCGACGCGCTGGGTGTGCGCGTCGCGCAGCAGATGCTGGCA
GGCGGCGCACGCGACATCCTCTCCATGCTGGGCGCCGACGCGCCACCCGCTACCTAA

Protein sequence :
MSSNARPTSRQSQLATTPAAQAPTKLVIASRESRLALWQAEHVRAALQKYYPACDVSILGMTTRGDQILDRSLAKVGGKG
LFVKELEVALAEGRADLAVHSLKDVPMQLPEGFALSTILEREDPRDAFVSNDYADLASLPAGAVVGTSSLRREASLRARF
PHLVIQPLRGNLDTRLGKLDRGDYAAIILAAAGLRRLGLADRIRSTIAPEESLPAAGQGALGIEIRADREEVRACLAPLH
DAPTALAVTAERAVSRILGGSCQVPLAAFAQWSGAGTLRLRAFVASQDGTRKLAADGEATPSTLADADALGVRVAQQMLA
GGARDILSMLGADAPPAT

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-48 55
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-48 55