Gene Information

Name : Rpic12D_2145 (Rpic12D_2145)
Accession : YP_002982091.1
Strain :
Genome accession: NC_012856
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 2280675 - 2281991 bp
Length : 1317 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATATCCAACTGCTGCGCAAAGACATCGACGCCGTCGCCGCGCGCCTCAAAGATCGCTGTTACGTGCTCGACGT
TGCCGGCTTTGCCGCACTCGAGGCGGAACGCAAGGCCATCCAGACCCGCACCGAAGAGCTGCAGGCCCGCCGCAACAGCC
TGTCCAAGCAGATTGGCATGCTCAAGGGCAAGGGCGAGGACGCATCGGGCGTGATGGCCGAGGTGTCGGGCATCGGCGAC
GAGCTGAAGGCGTCTGCCGCGCAACTCGACGTGGTGCAGGCGAAGTTGCAGGACCTGATGCTGTCGATCCCGAACCTGCC
GCACGAAAGCGTGCCGGCCGGACGCGACGAGACGCAGAACGTGGAAGTGCGCCGCGAGGGCACGCCGCGCACGTTCGATT
TCCCGGTCAAGGACCACGTCGATCTGGGCGCCGCGCTGGGGCTGGATTTTGATGCGGGTGCCAAGCTGTCCGGCGCGCGA
TTCACCGTCCTGAAAGGGCAGGTGGCGCGCCTGCATCGCGCGCTTGCGCAATTCATGCTCGACACGCACACGCTGGAGCA
CGGCTACACCGAGGCATACGTGCCGTACATCGTCAACGCTGCATCGATGCGTGGCACCGGTCAGTTGCCGAAGTTCGAGG
AAGACCTGTTCCGCGTGCCGCGCAAGATGGGGCACAGTGCCGAAGGCGAAGACGGCGAACGTGTCGAGAACTTCTACCTG
ATCCCGACCGCCGAAGTGCCGCTCACGAACCTCGTGCGCGATGAGATCGTCGCCGCCGATGCGCTGCCGATGATGTTCGC
GGCGCATTCGCCGTGCTTCCGTTCCGAAGCCGGCTCGTACGGCAAGGACACACGCGGCATGATCCGCCAGCACCAGTTCG
ACAAGGTGGAGATGGTGCAGATCGTGCAGCCCCAAACGTCGTTCGACGCGCTGGAAGCCATGACGAACGCCGCGGAGAAC
ATCCTGCGCAAGCTGGAATTGCCGTTCCGCACCGTCGTGCTGTGCACCGGCGACATGGGCTTCGGCAGCACCAAGACGTA
CGACATCGAGGTGTGGATTCCGGCGCAGAACACCTACCGCGAAATCAGCTCGTGCTCGAACATGGGCGACTTCCAGGCGC
GCCGCATGCAAGCGCGTTTCCGCAACGCGCAGGGCAAGCCGGAGCTGGTTCACACGCTCAACGGCTCGGGCCTCGCGGTG
GGCCGTGCGCTGGTTGCCGTGCTGGAGAACTACCAGAATGCGGATGGCTCGGTCACGGTGCCGACGGTGCTGCGCCCGTA
CCTGGGAGGCCAGGAAGTGCTGAAACCGGCTGCTTGA

Protein sequence :
MLDIQLLRKDIDAVAARLKDRCYVLDVAGFAALEAERKAIQTRTEELQARRNSLSKQIGMLKGKGEDASGVMAEVSGIGD
ELKASAAQLDVVQAKLQDLMLSIPNLPHESVPAGRDETQNVEVRREGTPRTFDFPVKDHVDLGAALGLDFDAGAKLSGAR
FTVLKGQVARLHRALAQFMLDTHTLEHGYTEAYVPYIVNAASMRGTGQLPKFEEDLFRVPRKMGHSAEGEDGERVENFYL
IPTAEVPLTNLVRDEIVAADALPMMFAAHSPCFRSEAGSYGKDTRGMIRQHQFDKVEMVQIVQPQTSFDALEAMTNAAEN
ILRKLELPFRTVVLCTGDMGFGSTKTYDIEVWIPAQNTYREISSCSNMGDFQARRMQARFRNAQGKPELVHTLNGSGLAV
GRALVAVLENYQNADGSVTVPTVLRPYLGGQEVLKPAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-100 54