Gene Information

Name : alr (Rpic12D_1310)
Accession : YP_002981271.1
Strain :
Genome accession: NC_012856
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 1383210 - 1384334 bp
Length : 1125 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCCAAGACCCATCCAGGCCGTCATCCACGGCCCAGCACTTGCCAATAATCTCCAGGTTGCCCGCCGTCATGCGCCCAA
CTCGCGCGTGTGGGCTGTCGTCAAAGCCAACGCGTACGGTCACGGCATCGAACGCGTGTATGAAGGCCTGCGCCAGACCG
ACGGTTTCGGCCTGCTCGATCTGGACGAGGCCGTCCGACTGCGCCAACTCGGCTGGCAGGGGCCGGTCCTCCTGCTCGAA
GGCTTTTTCAAGCCGGAAGACCTGGCCATCGTCGAGCAGTTCCGCCTGACCACCACCGTCCACTGCGAAGAGCAGCTTCG
CATGCTCGAACTGGCCCGCCCGAAAGGACCCATCAGCGTGCAGCTCAAGATCAATACGGGCATGAGCCGCCTCGGCTTCG
CGCCCGCTGCCTACCGCGCCGCATGGGAGCGCGCCCGCGCCATTTCGGGCGTCGGCACGATCGTCCACATGACGCATTTT
TCGGATGCCGACGGCCCGCGCGGCATCGAGCATCAACTTGTCGCGTTTGAACAGGCCACGCAGGGTTTGCCGGGCGAGGC
GTCGCTGTGCAACTCCGCGGCAACGCTGTGGCATCCGAAAGCACATCGCGACTGGGTGCGCCCCGGCGTGATCATGTACG
GCGCATCGCCGACGGGCGTGGCGGCGGACATCGACGGCACGGGGCTGATGCCCGCCATGACGCTCAAGAGCGAGCTGATC
GCCATTCAGGATCTGCAGCCCGGGGCGACGATCGGTTACGGCTCGCGCTTTACCGTGGAGCACCCGATGCGCATCGGCAT
CGTCGCGTGCGGTTATGCCGACGGCTACCCGCGCCATGCGCCAGGTTGGGACGGCAACCACACGCCGGTGCTGGTGGACG
GCGTGCGCACGCACATCGTGGGCCGCGTGTCGATGGACATGATTACCGTTGACCTGGCCGGGGTGCCCGAGGCGCGTGTC
GGCACGCCTGTCACCCTGTGGGGCGAGGGCCTGCCGATCGACGACGTTGCTCACGCTTCGGGCACGGTCGGGTATGAGCT
GATGTGCGCCCTGGCGCCCCGCGTACCGGTGTCGGTCGAGCCCGTCAGCACCGCGGACGCCGGCGACCTGGGCAAGGCTG
CCTGA

Protein sequence :
MPRPIQAVIHGPALANNLQVARRHAPNSRVWAVVKANAYGHGIERVYEGLRQTDGFGLLDLDEAVRLRQLGWQGPVLLLE
GFFKPEDLAIVEQFRLTTTVHCEEQLRMLELARPKGPISVQLKINTGMSRLGFAPAAYRAAWERARAISGVGTIVHMTHF
SDADGPRGIEHQLVAFEQATQGLPGEASLCNSAATLWHPKAHRDWVRPGVIMYGASPTGVAADIDGTGLMPAMTLKSELI
AIQDLQPGATIGYGSRFTVEHPMRIGIVACGYADGYPRHAPGWDGNHTPVLVDGVRTHIVGRVSMDMITVDLAGVPEARV
GTPVTLWGEGLPIDDVAHASGTVGYELMCALAPRVPVSVEPVSTADAGDLGKAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 8e-94 58