Gene Information

Name : guaA (Rleg_4571)
Accession : YP_002978348.1
Strain : Rhizobium leguminosarum WSM1325
Genome accession: NC_012850
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 4696598 - 4698160 bp
Length : 1563 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACCCAGACAGCACATCCCGACTCCGTTCTCATCGTCGATTTCGGCAGCCAGGTGACCCAGCTCATCGCACGACGCGT
GCGCGAGGCCGGTGTCTATTGCGAGATCGTTCCCTTCCAATCGGCCGAAGAGGGCTTCCACCGCCTGCAGCCGAAGGCCG
TGATCCTGTCCGGCAGCCCGGCTTCCACGGTGGACGAGGGATCGCCGCGAGCGCCTAACATCATCTTCGAGAGCGGCCTG
CCGGTGTTCGGCATCTGCTACGGCCAGCAGACGATGTGCATGCAGCTCGGCGGCAAGGTCGAGAGCGGCCATCACCGCGA
ATTCGGCCGCGCCTTCCTCGAGGTCGACAGGGACTGCCAGCTGTTCGAGGGCCTCTGGTCCTCCGGCTCGCGCCACCAAG
TCTGGATGAGCCATGGCGACCGCGTCACCGCGCTGCCGGATGGTTTCGAGGTGGTCGCCACCTCCTCCAACGCACCCTAT
GCCTTCATCGCCGACGAGAAGCGCAAATATTACGGCGTGCAGTTCCACCCCGAGGTCGTGCATACGCCTGATGGCGCCAA
GCTGATCGGCAACTTCATTCACAATATTGCCGGCCTCAAGGGCGACTGGTCGATGTCAGCCTATCGCCAGAAGGCGGTCG
AGCAGATCCGCGAACAGGTGGGCGACAAGCGCGTCATCTGCGCGCTTTCGGGCGGCGTCGACAGTTCCGTCGCAGCGCTG
TTGATCCACGAGGCCGTCGGCGACCAGCTGACCTGCATCCTCGTCGACCACGGGCTGATGCGCAAGGACGAGGCGGCCGG
CGTCGTCGCCATGTTCCGCGAGCACTACAATCTGCACCTGTTGCACGTCGATGCGGCCGATCGCTTCATCGGCGAACTCG
AGGGTGTCAGCGACCCGGAAACCAAGCGCAAGATCATCGGCCGGCTGTTCATCGAGACCTTCGAGGAAGAGGCAAAGAAG
CTCGGCGGCGCCGACTTCCTCGGCCAGGGCACGCTTTATCCCGACGTGATCGAGAGCGTTTCCTTCACCGGCGGCCCGTC
GGTGACGATCAAGTCGCACCACAATGTCGGCGGTCTGCCGGAGCGCATGAAGATGCAGCTCGTCGAGCCGCTGCGCGAGC
TCTTCAAGGACGAGGTGCGCGCACTCGGCCGCGAACTCGGCTTGCCCGACAGCTTCATCGGCCGTCACCCCTTCCCAGGC
CCGGGCCTGGCGATCCGTTGCCCCGGCGGCATCACCCGCGAAAAGCTGGAGATCCTGCGCGAGGCCGATGCGATCTATCT
CGACGAAATCCGTAAGGCCGGCCTCTACGACGCCATCTGGCAGGCCTTCGCCGTGCTGCTCCCCGTCCAGACCGTCGGCG
TCATGGGCGATGGGCGCACCTACGAATTCGTCTGTGCGCTGCGCGCCGTCACCTCCGTCGACGGCATGACGGCGGACTTC
TACCACTACGACATGGAATTCCTCGGCCGCGCCGCCACCCGCATCATCAACGAAGTGCGCGGCATCAACCGCGTGGTTTA
TGATGTGACGAGCAAGCCGCCCGGCACGATCGAGTGGGAGTGA

Protein sequence :
MTQTAHPDSVLIVDFGSQVTQLIARRVREAGVYCEIVPFQSAEEGFHRLQPKAVILSGSPASTVDEGSPRAPNIIFESGL
PVFGICYGQQTMCMQLGGKVESGHHREFGRAFLEVDRDCQLFEGLWSSGSRHQVWMSHGDRVTALPDGFEVVATSSNAPY
AFIADEKRKYYGVQFHPEVVHTPDGAKLIGNFIHNIAGLKGDWSMSAYRQKAVEQIREQVGDKRVICALSGGVDSSVAAL
LIHEAVGDQLTCILVDHGLMRKDEAAGVVAMFREHYNLHLLHVDAADRFIGELEGVSDPETKRKIIGRLFIETFEEEAKK
LGGADFLGQGTLYPDVIESVSFTGGPSVTIKSHHNVGGLPERMKMQLVEPLRELFKDEVRALGRELGLPDSFIGRHPFPG
PGLAIRCPGGITREKLEILREADAIYLDEIRKAGLYDAIWQAFAVLLPVQTVGVMGDGRTYEFVCALRAVTSVDGMTADF
YHYDMEFLGRAATRIINEVRGINRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-136 54
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-136 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-136 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-115 51