Gene Information

Name : thyA (Rleg_2802)
Accession : YP_002976602.1
Strain : Rhizobium leguminosarum WSM1325
Genome accession: NC_012850
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2783407 - 2784201 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAGCAATATCTCGATCTCTTGAATCATGTGATGGAAAAGGGCTCCGACCGGGGCGACCGCACCGGCACCGGCACGCG
CTCGGTCTTCGGCTACCAGATGCGCTTCGACCTCGAAGAGGGCTTCCCCGTCCTCACCACGAAGAAGCTGCATCTGCGCT
CGATCATTCACGAGCTTCTCTGGTTTCTGAAGGGCGAGACGAATATCCGATATCTCAAGGAAAACGGCGTTTCGATCTGG
GACGAATGGGCCGACGAAAACGGCGATCTCGGGCCGGTCTACGGCGCCCAGTGGCGCTCCTGGCCAGCGCCGGATGGCGG
CCATATCGACCAGATCGCCAATCTCGTCAAAGGCATCGTCAACAATCCGAATTCGCGTCGCCACATCGTTTCGGCCTGGA
ATCCGGCCGAAGTGGACGAAATGGCGCTGCCGCCCTGCCATTGCCTGTTCCAGTTCTATGTGGCTGACGGCAAGCTTTCC
TGCCAGCTCTACCAGCGGTCGGCCGATATCTTCCTCGGCGTGCCGTTCAACATCGCCTCCTATGCGCTGCTGACGATGAT
GGTGGCTCAGGTGACCGGGCTGAAGCCCGGCGATTTCGTTCACACGCTCGGCGACGCTCATCTCTATCACAACCATTTCG
ACCAGGCGAAGCTGCAACTGGCGCGCCGGCCGAAGCCGCTGCCGTTCATGCGCATCAAGCCTGATGTGAAGGACATTTTC
GGCTTCACCTTCGACGATTTCGAGCTGATCGGCTACGAGGCCGATGCCAGCATCAAGGCGCCGATCGCCGTCTGA

Protein sequence :
MKQYLDLLNHVMEKGSDRGDRTGTGTRSVFGYQMRFDLEEGFPVLTTKKLHLRSIIHELLWFLKGETNIRYLKENGVSIW
DEWADENGDLGPVYGAQWRSWPAPDGGHIDQIANLVKGIVNNPNSRRHIVSAWNPAEVDEMALPPCHCLFQFYVADGKLS
CQLYQRSADIFLGVPFNIASYALLTMMVAQVTGLKPGDFVHTLGDAHLYHNHFDQAKLQLARRPKPLPFMRIKPDVKDIF
GFTFDDFELIGYEADASIKAPIAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-74 60